Qvistdamborg9417

Juul is the most popular electronic cigarette on the market. Amid concerns around uptake of e-cigarettes by never smokers, can we detect whether someone uses Juul based on their social media activities? This is the central premise of the effort reported in this paper. Several recent social media-related studies on Juul use tend to focus on the characterization of Juul-related messages on social media. selleck chemicals llc In this study, we assess the potential in using machine learning methods to automatically identify Juul users (past 30-day usage) based on their Twitter data.

We obtained a collection of 588 instances, for training and testing, of Juul use patterns (along with associated Twitter handles) via survey responses of college students. With this data, we built and tested supervised machine learning models based on linear and deep learning algorithms with textual, social network (friends and followers), and other hand-crafted features.

The linear model with textual and follower network features performed best witheillance of Juul use based on social media data, including Juul usage patterns, nicotine dependence, and risk awareness.An outstanding challenge in modelling biomechanics after myocardial infarction (MI) is to estimate the so-called growth tensor. Since it is impossible to track pure growth induced geometry change from in vivo magnetic resonance images alone, in this work, we propose a way of estimating a surrogate or apparent growth tensor of the human left ventricle using cine magnetic resonance (CMR) and late gadolinium enhanced (LGE) images of 16 patients following acute MI. The apparent growth tensor is evaluated at four time-points following myocardial reperfusion 4-12 h (baseline), 3 days, 10 days and 7 months. We have identified three different growth patterns classified as the Dilation, No-Change and Shrinkage groups defined by the left ventricle end-diastole cavity volume change from baseline. We study the- trends in both the infarct and remote regions. Importantly, although the No-Change group has little change in the ventricular cavity volume, significant remodelling changes are seen within the myocardial wall, both in the infarct and remote regions. Through statistical analysis, we show that the growth tensor invariants can be used as effective biomarkers for adverse and favourable remodelling of the heart from 10 days onwards post-MI with statistically significant changes over time, in contrast to most of the routine clinical indices. We believe this is the first time that the apparent growth tensor has been estimated from in vivo CMR images post-MI. Our study not only provides much-needed information for understanding growth and remodelling in the human heart following acute MI, but also identifies novel biomarker for assessing heart disease progression.Epidemiological studies have reported association of urinary 3-phenoxybenzoic acid (3-PBA), a major metabolite of pyrethroid insecticides (PYRs), with respiratory disease. However, knowledge regarding its effect on pulmonary function in susceptible children is limited. This study aimed to assess the associations between environmental 3-PBA concentrations and pulmonary function in children aged 6-17 years. Using data on 1174 children aged 6-17 years from the U.S. National Health and Nutrition Examination Survey (NHANES) 2007-2012, the exposure to PYRs was assessed by measuring urinary 3-PBA concentrations and pulmonary function was assessed by spirometry. Multivariable linear regression and generalized linear models (GLMs) were used to examine the associations between 3-PBA concentrations and pulmonary function in children, controlling for confounders. We found that 3-PBA concentrations were inversely associated with forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), and peak expiratory flow (PEF) in the pediatric population (p-trends less then 0.05). link2 When stratified by age (6-10 and 11-17 years) and gender (boys and girls), the adverse effects of PYR exposures on pulmonary function were more pronounced among boys aged 11-17 years. Among this age group, 3-PBA concentrations were negatively associated with FEV1, FVC, forced expiratory flow between 25% and 75% of FVC (FEF25-75%), and PEF. However, among children aged 6-10 years, no associations were found between 3-PBA concentrations and any of the pulmonary function measures, in either boys or girls. Our findings suggest that environmental PYR exposures may adversely affect children's pulmonary function, with the strongest associations among 11-17 years old boys.Assessing the bioavailability of various Sb substances plays a crucial role in human health and the ecological risk assessment of contaminated soils. However, fate, behaviour and bioavailability of different Sb compounds in soils are insufficiently known. Therefore, in this present study, the effects of soil properties and ageing on bioavailability of four different Sb compounds (C8H4K2O12Sb2, Sb2S3, Sb2O3 and Sb2O3 nanoparticles) were evaluated during 120 days ageing time. A black soil (BS) with approximately 12% organic matter (OM) and a red soil (RS) with less than 1% OM were amended with 1000 mg Sb kg-1 of different Sb compounds and subjected to single extractions with distilled (DI) water, 2M HNO3, Simplified Bioaccessibility Extraction Test (SBET) and a modified Community Bureau of Reference (BCR) sequential extraction method. link3 The results revealed that there are substantial variations in dissolution rate of various Sb sources, depending upon soil type and Sb compound. The amounts of DI water extractability of Sb during the incubation time varied between less then 1% and 2%, whereas HNO3 extractable fractions and Sb bioaccessibility at the end of ageing time ranged between about 1%-3% and less then 1%-9% of the total Sb, with maximum bioaccessibility observed in BS contaminated with C8H4K2O12Sb2. The residual and labile fractions accounted for 77-93% and 0.1-4% of the total Sb, respectively, indicating that Sb is mostly associated with recalcitrant fractions of the soils. The results of single and sequential extraction studies revealed that source of Sb, ageing time and soil properties can greatly affect the bioavailability of Sb in soils. The findings of this research provide a deeper understanding of the potential risks associated with Sb compounds and highlights the role of site-specific considerations for improving the robustness of toxicity guidelines and long-term management of Sb contaminated sites.Understanding the migration and conversion of nitrogen in wood-based panels (WBPs) during pyrolysis is fundamentally important for potentially transforming the N-containing species into valuable material-based products. This review firstly summarizes the commonly used methods for examining N evolution during the WBPs pyrolysis before probing into the association between the wood and adhesives.The potential effects of wood-adhesive interaction on the pyrolysis process are subsequently analyzed. Furthermore, the controversial statements from literature on the influence of adhesives on wood pyrolysis behavior are discussed, which is followed by the detailed investigation into the distribution and evolution of N-containing species in gas, liquid and char, respectively, during WBPs pyrolysis in recent studies. The differences in N species due to the heating sources (i.e. electrical heating vs microwave heating) are particularly compared. Finally, based on the characteristics of staged pyrolysis, co-pyrolysis and catalytic pyrolysis, the converting pathways for WBPs are proposed with an emphasis on the production of value-added chemicals and carbon materials, simultaneously mitigating NOx emission.Facile modification is a common, but effective, option to improve the uptake removal capacity of of activated carbon (AC) against diverse target volatile organic compounds (VOCs; e.g., benzene) in gaseous streams. To help design the routes for such modification, this research built strategies to generate three types of modified ACs by incorporating amine/sulfur/amino-silane groups under solvothermal or microwave (MW) thermal conditions. The adsorption performance has been tested using a total of six types of AC sorbents (three modified + three pristine forms) for the capture of 1 Pa benzene (1 atm and 298 K). The obtained results are evaluated in relation to their textural properties and surface functionalities. Accordingly, the enhancement of AC surface basicity (e.g., point of zero charge (PZC) = 10.25), attained via the silylation process, is accompanied by the reduced adsorption of benzene (a weak base). In contrast, ACs amended with amine/sulfur (electron-donating) groups using the MW technique are found to acquire high surface acidity (PZC of 5.99-6.05) to exhibit significantly improved benzene capturing capability (relative to all others). Their uplifted performance is demonstrated in terms of key performance metrics such as breakthrough volume (BTV10% 163 → 443 L g-1), adsorption capacity (Q10% 4.82 → 13.6 mg g-1), and partition coefficient (PC10% 0.516 → 1.67 mol kg-1 Pa-1). Based on the kinetic analysis, the overall adsorption process is found to be governed by pore diffusion as the main rate-determining step, along with surface interaction mechanisms. The results of this research clearly support the critical role of surface chemistry of AC adsorbents and their textural properties in upgrading air/gas purification systems.Tea plant is capable of hyper-accumulating fluoride (F) in leaves, suggesting drinking tea may cause excessive F intake in our body and threaten the health. This study investigated the changes in the structure, composition, and F content in the leaf cell wall of the tea (Camellia sinensis) under different F conditions to demonstrate the role of cell wall in F enrichment in tea plants. The cell wall was shown as the main part for F accumulation (67%-92%), with most of F distributed in the pectin fraction (56%-71%). With increasing F concentration, a significant increase (p less then 0.05) was observed in the F content of cell wall and its components, the level of cell wall metal ions (i.e. Cu, Mg, Zn, Al, Ca, Ba, Mn), as well as the content of total cell wall materials, cellulose, and pectin. Meanwhile, the level of Cu, Mg, Zn, pectin, and cellulose was significantly positively correlated with the F content in the leaf cell wall. F addition was shown to increase the fluorescence intensity of LM19 and 2F4 antibody-labeled low-methylesterified homogalacturonans (HGs), while decrease LM20-labeled high-methylesterified HGs, coupled with an increase in the activity and gene expression of pectin methyl esterases (PMEs) in tea leaves. All these results suggest that F addition can increase pectin content and demethylesterification, leading to increased absorption of metal cations and chelation of F in the cell wall through the action of metal ions.Antibiotic resistance is exacerbated by the exchange of antibiotic resistance genes (ARGs) between microbes from diverse habitats. Plasmids are important ARGs mobile elements and are spread by horizontal gene transfer (HGT). In this study, we demonstrated the presence of multi-resistant plasmids from inhalable particulate matter (PM) and its effect on gene horizontal transfer. Three transferable multi-resistant plasmids were identified from PM in a hospital, using conjugative mating assays and nanopore sequencing. pTAir-3 contained 26 horizontal transfer elements and 10 ARGs. Importantly pTAir-5 harbored carbapenem resistance gene (blaOXA) which shows homology to plasmids from human and pig commensal bacteria, thus indicating that PM is a media for antibiotic resistant plasmid spread. In addition, 125 μg/mL PM2.5 and PM10 significantly increased the conjugative transfer rate by 110% and 30%, respectively, and augmented reactive oxygen species (ROS) levels. Underlying mechanisms were revealed by identifying the upregulated expressional levels of genes related to ROS, SOS, cell membranes, pilus generation, and transposition via genome-wide RNA sequencing.