Nygaardcurry1679

The purpose of this study was to clarify the diagnostic accuracy of the mobile assessment of varus thrust using inertial measurement units (IMUs).

A total of 80 knees in 49 patients were enrolled in this study. On visual analysis of gait to determine the presence or absence of varus thrust, 23 knees were assigned to the Present group, 17 to the Ambiguous group, and 40 to the Absent group. The peak knee varus angular velocities (PVVs), measured by quantitative gait analysis using nine-axis IMUs, were compared between these three groups. A receiver operating characteristic curve for the relationship between the visual assessment of varus thrust (Present and Ambiguous) and the measured PVV was created, and the cut-off PVV for visualized varus thrust was determined as the highest point for both sensitivity and specificity.

The mean PVVs were significantly different between the three groups (Present, 47.7 ± 8.2 degree/s, Ambiguous, 34.1 ± 10.5 degree/s, and Absent, 28.1 ± 8.3 degree/s, respectively, ANOVA P=0.000). The PVV cut-off value for visualized varus thrust was 28.1 degree/s, yielding a sensitivity of 0.957 and a specificity of 0.579.

A PVV <28.1 degree/s is useful for ruling out varus thrust during gait. This quantitative varus thrust assessment method using IMUs has clinical utility as a screening test.

A PVV less then 28.1 degree/s is useful for ruling out varus thrust during gait. This quantitative varus thrust assessment method using IMUs has clinical utility as a screening test.

We aimed to identify the quadriceps muscle strength (QMS) thresholds below which exercise capacity is compromised in men with chronic obstructive pulmonary disease (COPD).

We measured the quadriceps isometric maximum voluntary contraction (QMVC) and calculated the QMVC values normalized to weight (QMVC-BW), height squared (QMVC-H

), and body mass index (QMVC-BMI) in 113 patients with COPD. The functional exercise capacity was evaluated using the 6-minute walk distance (6MWD), and 6MWD <350 m was defined as functional exercise intolerance. Thresholds were determined for QMVC and its normalized values to achieve high specificity (>0.90) with maximal sensitivity. P-values <0.01 were considered statistically significant.

Data from 99 male patients (age, 74 ± 6 years; percentages of predicted forced expiratory volume in 1-s, 56.9 ± 26.4%) were analyzed; 3 women and 11 participants with the missing data were excluded. Multivariate logistic regression models identified significant associations of QMVC and QMVC-H

with 6MWD, after adjustment for age and dyspnea. C-statistics showed that the area under the curves of all QMVC parameters were comparable. The thresholds of QMVC and QMVC-H

for predicting compromised exercise capacity were 26.2 kg and 9.6 kg/m

, respectively.

QMS thresholds in men with COPD could help clinicians evaluate whether QMS is insufficient to achieve 6MWD ≥350 m and thereby identify patients who should be specifically targeted for muscle strengthening training during their pulmonary rehabilitation program.

QMS thresholds in men with COPD could help clinicians evaluate whether QMS is insufficient to achieve 6MWD ≥350 m and thereby identify patients who should be specifically targeted for muscle strengthening training during their pulmonary rehabilitation program.

Endoscopists and endoscopic assistants are easily exposed to germs, including COVID-19, during aerosol-generating procedures such as gastrointestinal endoscopy. This retrospective study investigated the utility of a box-shaped shielding device for reducing the risk of COVID-19 droplet infection during endoscopic procedures.

We created a cuboid box (500 × 650 × 450 mm) with four sides were covered with a transparent, vinyl-chloride sheet having two windows for endoscopic passage and assistance. The shielding box was then placed over a patient's head and shoulders and covered with another transparent vinyl sheet. We assessed its utility and safety using the medical data concerning the procedure time and vital signs and a questionnaire for the endoscopic staff and patients.

We performed endoscopic retrograde cholangiopancreatography-related procedures using this device for two patients suspected of having COVID-19-associated pneumonia. Both patients were smoothly and successfully treated without any complications. No difficulties were noted with either endoscopic operation or in assisting the procedure, and the transparency was good enough to observe the patients' faces and movements.

This box-shaped shielding device can be used to reduce the risk of COVID-19 droplet infection during endoscopic procedures in the clinical setting.

The COVID-19 outbreak has reminded healthcare personnel working in endoscopy units of the importance of infection prevention during endoscopy. The box-shaped shielding device can help endoscopic staff avoid hospital-setting COVID-19 infection.

The COVID-19 outbreak has reminded healthcare personnel working in endoscopy units of the importance of infection prevention during endoscopy. The box-shaped shielding device can help endoscopic staff avoid hospital-setting COVID-19 infection.

Late side effects of radiotherapy (RT) in the treatment for head and neck (HN) malignancies involve an inadequate healing response of the distressed tissue due to RT-induced hypovascularity. The aim of this study was to develop a pilot model in which vascular alterations associated with the onset of late irradiation (IR) injury could be measured in rabbit oral mucosa and mandibular bone.

Eight male New Zealand white rabbits were divided over four treatment groups. Group I-III received four fractions of RT (5.6 Gy, 6.5 Gy, and 8 Gy, respectively) and Group IV received 1 fraction of 30 Gy. Oral microcirculatory measurements were performed at baseline (before RT) and once a week during 11 consecutive weeks after RT assessing perfusion parameters, that is, total vessel density (TVD), perfused vessel density (PVD), proportion of perfused vessels (PPV), and microvascular flow index (MFI). G150 solubility dmso Post-mortem histopathology specimens were analyzed.

Five weeks after RT, TVD, and PVD in all groups showed a decrease of >10% compared to baseline, a significant difference was observed for Groups I, II, and IV (

<0.