Nortonallen9719

Schizencephalies are abnormal clefts of the cerebral hemispheres that result from abnormal late neuronal migration and cortical organization. In the present study, we report a different type of unusual motor organization in a patient with a schizencephalic cleft in the right hemisphere and polymicrogyria in the opposite hemisphere. Despite similar brain pathology affecting the sensorimotor cortex, motor organization differed from previously known bilateral congenital brain lesions. We conducted a transcranial magnetic stimulation (TMS) and diffusion tensor image (DTI) study to confirm the motor organization. this website In this case, ipsilateral corticospinal projections to the paretic hands were observed during TMS of the less affected hemisphere, along with polymicrogyria, similar to the previous study. However, a crossed corticospinal tract to the paretic hand from the more severely affected hemisphere was observed in this case-a pattern of motor organization that has yet to be reported in this patient population. Our findings indicate that motor organization after early brain injury may be affected by the interhemispheric competition of the corticospinal system and bilateral brain lesions, thereby resulting in unilateral hemiparesis.The feasibility of the random subspace ensemble learning method was explored to improve the performance of functional near-infrared spectroscopy-based brain-computer interfaces (fNIRS-BCIs). Feature vectors have been constructed using the temporal characteristics of concentration changes in fNIRS chromophores such as mean, slope, and variance to implement fNIRS-BCIs systems. The mean and slope, which are the most popular features in fNIRS-BCIs, were adopted. Linear support vector machine and linear discriminant analysis were employed, respectively, as a single strong learner and multiple weak learners. All features in every channel and available time window were employed to train the strong learner, and the feature subsets were selected at random to train multiple weak learners. It was determined that random subspace ensemble learning is beneficial to enhance the performance of fNIRS-BCIs.Whereas the fundamental role of the body in social cognition seems to be generally accepted, elucidating the bodily mechanisms associated with non-verbal communication and cooperation between two or more persons is still a challenging endeavor. In this article we propose a fresh approach for investigating the function of the autonomic nervous system that is reflected in parameters of heart rate variability, respiration, and electrodermal activity in a social setting. We analyzed autonomic parameters of dyads solving a target-tracking task together with the partner or individually. A machine classifier was trained to predict the subjects' rating of performance and collaboration either from tracking error data or from the set of autonomic parameters. When subjects collaborated, this classifier could predict the subjective performance ratings better from the autonomic response than from the objective performance of the subjects. However, when they solved the task individually, predictability from autonomic parameters dropped to the level of objective performance, indicating that subjects were more rational in rating their performance in this condition. Moreover, the model captured general knowledge about the population that allows it to predict the performance ratings of an unseen subject significantly better than chance. Our results suggest that, in particular in situations that require collaboration with others, evaluation of performance is shaped by the bodily processes that are quantified by autonomic parameters. Therefore, subjective performance assessments appear to be modulated not only by the output of a rational or discriminative system that tracks the objective performance but to a significant extent also by interoceptive processes.Recent methodological advances in studying large scale animal movements have let researchers gather rich datasets from behaving animals. Often collected in small sample sizes due to logistical constraints, these datasets are however, ideal for multivariate explorations into behavioral complexity. In behavioral studies of domestic dogs, although automated data loggers have recently seen increasing use, a comprehensive framework to identify complex behavioral axes is lacking. Dog behavioral studies frequently rely on subjective ratings, despite demonstrable evidence that these are insufficient for identifying behavioral variables. Taking advantage of dogs' innate running abilities and readily available GPS data loggers, we extracted latitude-longitude coordinates from running dogs in a large field setup. By extracting multiple variables from each logged coordinate, we generated a complex dataset from limited numbers of dog runs. Individual variables were successful in classifying aerobic competence, social awareness, and different exploratory patterns of dogs. Multivariate analyses identified latent features in movement patterns of dogs which were primarily comprised of two behavioral axes spatial acuity and social awareness. Individual dogs were then behaviorally classified into independent clusters through unsupervised learning. Interestingly, even though field dogs clustered primarily with each other in varying degrees of energetic exploration and handler focus, some house pets displayed moderately high exploration abilities as well. We expect our proof of principle quantitative pipeline to provide a robust framework for behavioral classification, generating case-control clusters based solely on complex behavioral axes, and greatly benefiting genetic association studies of dog behavior.Temporal information about food availability can be easily entrained, as in the case of fixed feeding routines of captive animals. A sudden unintentional or deliberate delay (e.g., food deprivation-FD) leads to frustration and psychological stress due to the loss of temporal predictability. How marmosets-an increasingly used small primate-process and respond to FD stress has not been previously assessed. Here we delayed the routine feeding of adult captive marmosets for 3 or 6 h. Blood cortisol concentration was used as a hormonal measure of the stress response. Changes in the left/right baseline tympanic membrane temperature (TMT) were used as an indirect ipsilateral indicator of hemisphere activity. Marmosets that were deprived for 3 h had higher cortisol levels than non-deprived controls. Cortisol concentration in the marmosets deprived for 6 h did not differ from controls possibly due to adaptative mechanisms against the detrimental effects of prolonged high cortisol levels. Interestingly, FD stress may have been processed more symmetrically at first, as indicated by the bilateral increase in TMT at the 3 h interval.