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Chemotherapy is the first-line treatment for symptomatic patients. Unless the condition is life threatening, radiotherapy is not indicated. Surgical resection may be indicated in younger infants with localized tumors and favorable biology, but otherwise, it is not usually indicated for residual cases.

Our data confirm that NBL-4S is a curable cancer, especially with early recognition and intervention. Chemotherapy is the first-line treatment for symptomatic patients. Unless the condition is life threatening, radiotherapy is not indicated. Surgical resection may be indicated in younger infants with localized tumors and favorable biology, but otherwise, it is not usually indicated for residual cases.

To identify the self-reported vaccine-related side effects among healthcare professionals (HCPs) in the Jazan province, Saudi Arabia, and determine the associated socio-demographic factors. With the recent second and third waves of coronavirus disease -19 (COVID-19) infections worldwide, the race is not only to encourage but also to achieve mass vaccination.

A total of 397 HCPs from across Jazan province participated in an anonymous online cross-sectional survey conducted for a period of 45 days (March 30, 2021 to May 13, 2021) in Jazan province, Saudi Arabia. Data was collected using a validated 22-items self-report survey.

For both COVID-19 vaccines, majority of reports were related to flu-like symptoms including fever, chills, headache, fatigue, tiredness, and myalgia. Statistically significant associations were observed between the severity of side effects and gender (χ

=73.32;

<0.001), type of vaccine (χ

=112.08;

<0.001), and presence of known allergies (χ

=99.69;

<0.001). Female HCPs were more likely to report any side effects compared with male HCPs (adjusted odds ratio [AOR] 3.72;

<0.001). Furthermore, HCPs with known allergies were more likely to report any side effects than their counterparts with unknown allergies (AOR 16.29;

<0.001).

The findings of the present study would help in designing educational programs aimed at combating the misconstrued fear of vaccination and highlighting the urgent need of getting vaccinated. This study also helps in the identification of factors affecting the presence and severity of side effects.

The findings of the present study would help in designing educational programs aimed at combating the misconstrued fear of vaccination and highlighting the urgent need of getting vaccinated. This study also helps in the identification of factors affecting the presence and severity of side effects.

To assess the clinical and epidemiological characteristics of hospitalized cancer patients with skin and soft-tissue infections (SSTIs).

An observational retrospective study was conducted between March 2016 and December 2020 at the Oncology Department of King Saudi Medical City, Riyadh, Saudi Arabia. Patients with complicated and uncomplicated SSTIs were included.

A total of 204 cancer patients with SSTIs were evaluated. The incidence of SSTIs was 1.67% (204/12,203). Breast cancer (39%) was the most common solid tumor in all patients with SSTIs. Exit site infection (n=84, 41.2%) was the most common SSTI in cancer patients, followed by wound infection (n=72, 35.3%), and cellulitis (n=44, 21.5%). The majority of patients received appropriate antimicrobial therapy (n=150, 73.5%).

This study has shown a modest incidence of SSTIs in hospitalized cancer patients, with many of the patients received appropriate antimicrobial therapy.

This study has shown a modest incidence of SSTIs in hospitalized cancer patients, with many of the patients received appropriate antimicrobial therapy.

To explore the benefits of invoking unconscious sentiment to improve the treatment of stuttering and misarticulation.

This cross-sectional study of 80 participants with speech issues (44 patients with misarticulation and 36 with stuttering) who underwent comprehensive speech and hearing evaluations to confirm and diagnose speech difficulties. Speech and language pathologists then calculated either the percentage of correctly pronounce sounds in misarticulation cases or stuttering severity index-4 scores in cases of stuttering following the use of therapeutic stimuli recorded with familiar and non-familiar voices of similar linguistic and phonetic complexity. Descriptive and inferential statistics were used to compare the data collected following the use of familiar and unfamiliar stimuli.

The analysis showed that the number of dysfluencies in cases of stuttering were significantly fewer when employing familiar voices than unfamiliar voices (3% errors vs 12% errors; Z= -5.16

<0.001). Additionally, ttherapy and maximizing therapeutic outcomes. This study also recommends engaging families and friends in providing speech services to the speech-impaired population to improve patient progress.

To evaluate the outcomes of cirrhotic patients admitted to the intensive care unit (ICU) following cardiac arrest.

This was a single centre retrospective study of all the cirrhotic patients, admitted to the ICU at King Abdulaziz Medical City, Riyadh, Saudi Arabia, after a successful cardiac arrest resuscitation, from 1999 to 2017. The characteristics of the hospital survivors and non-survivors were compared.

A total of 76 patients were admitted to the ICU during the study period, with a median age of 64 years. In addition to cirrhosis, the patients had other chronic comorbidities, including chronic renal disease (32.9%) and diabetes (47%). Of this group, 67 (88.2%) died in the hospital, and 54 (71%) died while in ICU. Compared to the group who survived, all non-survivors required mechanical ventilation and had a higher median APACHE II score of 38 (

=0.006), a lower median Glasgow coma score (GCS) of 3 (

=0.0003), and a higher median lactic acid of 6.4 mmol/L (

=0.032). On multivariable logistic regression analysis, the important predictors of hospital mortality were APACHE II score (

=0.006), bilirubin level (

=0.008) and GCS (

=0.005).

Cirrhotic patients admitted to the ICU following cardiac arrest have high mortality. Patients with higher APACHE II scores, higher bilirubin and lower GCS have higher risk of in-hospital mortality.

Cirrhotic patients admitted to the ICU following cardiac arrest have high mortality. Patients with higher APACHE II scores, higher bilirubin and lower GCS have higher risk of in-hospital mortality.

To determine the prescription pattern of proton pump inhibitors (PPIs) at a tertiary hospital in Saudi Arabia.

This study was a retrospective cohort design using medical records at the medical ward of King Abdulaziz University Hospital (KAUH), Jeddah, Saudi Arabia. Data were collected from medical records of all patients admitted to the ward from October 2019 to March 2020.

A total of 1135 medical records were retrieved, of which 709 (62.5%) were prescribed PPIs. The frequency of PPIs prescribed was highest in March 2020 (21.7%) relative to the remaining months. Omeprazole was the most prescribed PPI (84.5%), compared to pantoprazole (15.5%). The PPIs were commonly administered through oral (56.7 %), compared to intravenous route (43.3%). Y-27632 manufacturer The PPIs were prescribed to most patients (58.4%) on the first day of admission, and 6.5% were prescribed for indications other than those approved by the Food and Drug Administration.

This study demonstrates that PPIs are frequently prescribed among most patients at the medical ward of KAUH, Kingdom of Saudi Arabia. We found that the PPIs were prescribed to many patients inappropriately (not based on clinical guidelines). These results suggest the need for educational interventions among physicians on rational prescription.

This study demonstrates that PPIs are frequently prescribed among most patients at the medical ward of KAUH, Kingdom of Saudi Arabia. We found that the PPIs were prescribed to many patients inappropriately (not based on clinical guidelines). These results suggest the need for educational interventions among physicians on rational prescription.

To assess prevalence and perception of sleep paralysis and its relationship with socioeconomic determinants, and risk factors in a cross-sectional sample of Saudi general population from Al-Ahsa city.

A cross-sectional sampling survey was conducted during 2020 to 2021. The targets were aged above 18 and belonged to Al-Ahsa. Patients were sent self-reported anonymous questionnaires to complete.

A total of 524 participants, whose ages ranged from 18 to 60 years, were analyzed. Among 85.7% of participants aged 55 years and over, compared to 65.8% of those who were aged under 35, 379 (72.3%) respondents were females. Moreover, 438 (83.6%) participants were university graduates, 271 (51.7%) were students and 40.8% had psychological disorders including anxiety (25.2%) and depression (5.7%). Family history of sleep paralysis was reported by 369 (70.4%) participants. A total of 97.5% study participants were aware of sleep paralysis.

Sleep paralysis is a common occurrence in people residing in Al-Ahsa, Saudi Arabia. A considerable number of the society held wrong beliefs regarding sleep paralysis. Therefore, raising public of identity of sleep paralysis is crucial. We recommend applying the study in other cities within Saudi Arabia to identify common risk factors and perceptions among the society.

Sleep paralysis is a common occurrence in people residing in Al-Ahsa, Saudi Arabia. A considerable number of the society held wrong beliefs regarding sleep paralysis. Therefore, raising public of identity of sleep paralysis is crucial. We recommend applying the study in other cities within Saudi Arabia to identify common risk factors and perceptions among the society.

To delineate the relation between shift work and glycemic control among the healthcare workers (HCWs) with diabetes mellitus (DM) in the hospitals of Dammam, Saudi Arabia.

A cross-sectional study was conducted among HCWs with DM working in 3 hospitals in Dammam, Saudi Arabia, from November 2018 to January 2019. The study participants answered a self-administered questionnaire related to sociodemographic data, work-related questions, diabetes-related questions, the latest hemoglobin A1C test outcome, and self-management activities. The Chi-square and t-test were used to determine the association between the risk factor of glycemic control and shift work.

The HCW's ages ranged from 24-60 years. The mean age of the employees in the day shift was 42.4±7.7 years and night shift was 42.1±7.3 years. The significant difference between daytime workers and shift workers was observed in terms of occupation, and obesity. Day shift employees reported being significantly more physically active than shift workers. The daily day shift led the employee to miss their routine clinic visits for DM. Shift workers had more weight gain due to unhealthy food intake, sleep deprivation, and improper physical activity when compared with daytime employees. Anti-clockwise shift rotation significantly demonstrated that 92.9% of employees developed uncontrolled DM.

Glycemic control was worsened among the shift worker with DM compared to daytime workers.

Glycemic control was worsened among the shift worker with DM compared to daytime workers.

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