Maynardlindgaard6719

Arteriovenous Fistula (AVF) is an essential requirement in Hemodialysis (HD) to remove toxins and excess fluid from the blood of patients with Chronic Renal Failure (CRF). The Blood Flow Rate (BFR) in AVF is an important factor in the success of HD. Due to a lack of studies of low BFR during HD, this study was conducted. The objective of this study was to compare the success rate of HD in patients with a BFR = 400-500 mL min-1 (group-2), in comparison to those of higher BFR (group-1).

This prospective cohort study was conducted at the ultrasound Doppler (USD) unit in King Fahad Hospital in Almadinah from July to December, 2019. In this study, 44 patients underwent AVF for HD and were assessed by USD for 2 consecutive visits at 3 months intervals. The success rate of HD was measured in patients with a BFR = 400-500 mL min-1 and in those with BFR>500 mL min-1. A comparison of the success rate in the 2 groups was done.

Among the 44 patients, 59% were males and 41% were females. The age of participants ranged from 20-80 years (mean 46.75±13.67 years). The patients underwent HD 3 or 2 session's week-1 for 3 or 4 hrs (mean 3.84±0.36 h) per session. In the first assessment, the success rate was 100% in both groups but it was 88.24% in group-1 and 70% in group-2 in the second assessment.

The success rate of hemodialysis in patients with BFR 400-500 mL min-1 in AVF was acceptable in comparison to that in patients with BFR>500 mL min-1.

500 mL min-1.

Postharvest disease caused by Colletotrichum spp. caused major losses. The species of Colletotrichum are difficult to distinguish if only seen from their morphology. This study investigated Colletotrichum isolates associated with tropical fruits anthracnose using multi-genetic analysis and the cross-infection potency of each isolate among tropical fruits.

The fruit samples were collected from markets in the Special Region of Yogyakarta, Indonesia and its surrounding area. The fruits affected by anthracnose subjected to isolation, resulting in 15 isolates. Selleckchem Atezolizumab Morphology of colony and conidia then characterized and clustered with UPGMA. The seven representative isolates were selected for molecular identification. The multi-genetic analysis was used by combining ITS, Glyceraldehyde 3-phosphate dehydrogenase (gapdh) and tub2 sequence genes. A cross-infection test was conducted by using selected species from the multi-genetic analysis.

Multi-genetic analysis clustered the selected isolates into four species. Isolates from banana, avocado, papaya and citrus belonged to gloeosporioides species complex, including C. siamense, C. asianum and C. gloeosporioides. Isolates from apple, guava, mango and citrus belonged to acutatum species complex, including C. sloanei. The cross-infection test in this study showed that C. siamense could cause anthracnose on banana, apple, citrus and avocado, C. asianum on avocado, papaya, apple and citrus, C. gloeosporioides on citrus and apple, C. sloanei on apple, guava, citrus and papaya.

The C. siamense, C. asianum, C. gloeosporioides and C. sloanei found associated with tropical fruits anthracnose. The potency of the cross-infection test revealed the board range in the pathogenicity of the Colletotrichum isolates.

The C. siamense, C. asianum, C. gloeosporioides and C. sloanei found associated with tropical fruits anthracnose. The potency of the cross-infection test revealed the board range in the pathogenicity of the Colletotrichum isolates.

The worldwide fly species, Muscina stabulans (Diptera Muscidae) is known as 'false stable fly'. It has veterinary, forensic and medical importance. The present study aimed to examine the toxicity of novaluron (chitin synthesis inhibitor) via its effect on the growth and reproductive potential of M. stabulans.

The early last (3rd) instar larvae and prepupae have been treated with novaluron using five doses 5.0, 1.0, 0.5, 0.1 and 0.01 μg/larva. Student's t-test analysis has been used for data processing as well as refined by Bessel correction for significant differences among means.

Current study revealed that, after the treatment different mortalities of larva, pupa and adult have been estimated. LD50 values of novaluron were 0.018 and 0.057 μg/insect, respectively. Furthermore, the larval period was insignificantly shortened while the pupal duration has been significantly extended and the developmental rate has been slightly enhanced. On the other hand, the adult longevity of females was considerably reduced and the adult emergence was considerably blocked, regardless the dose. However, only after the treatment, some deformed pupae were observed and some adult deformities were observed. Both fecundity and fertility were drastically reduced and sterilizing activity on novaluron increased in a dose-dependent course, regardless the time of treatment.

Novaluron can be used as an effective IGR in the integrated control program for this medically and veterinary serious fly.

Novaluron can be used as an effective IGR in the integrated control program for this medically and veterinary serious fly.

The natural bioactive compounds of Curcuma longa, known as curcuminoids, has been shown to exerts anticancer effects to diverse cancer cell line in vitro, including breast cancer cell line. These curcuminoids consist of curcumin (Cur), demethoxycurcumin (DMC) and bisdemethoxycurcumin (BDMC). Furthermore, there has never been a study to compare the extent of antiproliferative and apoptotic modulation potential between Cur, DMC and BDMC in the breast cancer cell, until now. In the present study, we explore the efficacy among Cur, DMC and BDMC to alters MCF-7 cell viability, which might lead to apoptotic modulation.

This kind of study was performed in vitro whereby the cells were maintained in an appropriate medium and the anticancer effect of curcuminoids (Cur, DMC and BDMC) was measured by using resazurin-based PrestoBlue cell viability assay. Later, MCF-7 breast cancer cells were cultured in 12 wells plate added with different concentrations of Cur, DMC and BDMC for western blotting analysis. Statistical analysis was performed with GraphPad 8, One-way ANOVA and Student's t-test.

The result showed that Cur, DMC and BDMC inhibiting the proliferation of MCF-7 cells. In the concentration dose of 31.25 μg mL-1, the cell viability in cells treated with Cur is 27%, DMC is 31.5% and BDMC is 46%. The IC50 dose of Cur, DMC and BDMC were 25.63, 29.94 and 36.91 μg mL-1.

Cur is more effective in inhibiting proliferation and apoptotic modulation in MCF-7 cells compare to DMC and BDMC. It represents the potential of Cur, DMC and BDMC as adjunctive therapy in treating breast cancer.

Cur is more effective in inhibiting proliferation and apoptotic modulation in MCF-7 cells compare to DMC and BDMC. It represents the potential of Cur, DMC and BDMC as adjunctive therapy in treating breast cancer.