Mackkorsholm1666

This overview concludes with important issues to address when treating sexual problems among CSA survivors and a call for additional evidence-based practices for treating sexual problems among survivors of CSA.

To identify potential mutations of the FXII gene (

) in a consanguineous marriage family with hereditary coagulation factor XII (FXII) deficiency, and it will improve the understanding of the pathogenesis involved in the disease.

The proband was a 58-year-old male who had chronic gastritis. He was found to have a significantly prolonged activated partial thromboplastin time (APTT) at 101.0s (reference range, 29.0-43.0 s) before

.

The coagulation factor XII activity (FXIIC) and FXII antigen (FXIIAg) were measured by one-stage clotting assay and enzyme-linked immunosorbent assay, respectively. The

gene was amplified by polymerase chain reaction and sequenced. Mutation sites were further confirmed by reverse sequencing. The conservatism and possible impact of the amino acid substitution were analyzed by multiple bioinformatics tools, as well as 3D protein model analysis.

The proband had a prolonged APTT (101.0 s), whose FXIIC and FXIIAg were obviously reduced, both at 1.0% (normal range, 72-113%). Gene sequencing revealed that he carried a homozygous missense mutation of Met527Ile. Family study showed that his mother, son and daughter carried a heterozygous Met527Ile. Bioinformatics and model analysis of the mutation indicated that Met527Ile may be detrimental and potentially alters the structure and the function of the protein.

The novel mutation Met527Ile could potentially account for the reduced activity of FXII in this family.

The novel mutation Met527Ile could potentially account for the reduced activity of FXII in this family.Purpose In order for health professionals to encourage pregnant women with a low socioeconomic status (SES) to move towards empowerment for a healthy dietary intake, crucial steps are to understand the perspectives of pregnant women of food and eating and to identify opportunities for empowerment. This study aimed to examine the perspectives of pregnant women on food and eating and to identify the opportunities for empowerment towards a healthy dietary intake. Methods This was a qualitative participatory study. Thirteen semi-structured interviews were conducted with low SES pregnant women in the Netherlands and analysed using an inductive approach. Results Five perspectives on food and eating emerged 1) health-promoting foods and products, 2) challenges in healthy eating, 3) risky products, 4) strategies for healthy eating, and 5) motivational aspects. Opportunities for empowerment were searching balanced and personalized information, developing strategies to implement healthy diets, navigating the social environment, and dealing with different motivations. Conclusion Pregnant women hold diverse perspectives regarding food and eating, signalling the need to adjust dietary support from health-care professionals. Professionals in antenatal care could optimize their interactions by engaging in pregnant women's empowerment processes to make healthy modifications to their dietary intake.This study explores the green synthesis of nano zero-valent iron (nZVI) extracted from the peel of selected waste fruits banana (BP), mango (MP), and pomegranate (GP), for the removal of nutrients from aqueous environments. The extract was prepared by heating de-ionised water at 60°C for 5 min, adding a reducing and a stabilising agent, FeCl3, then stirring with a N2 gas flush solution to form iron nanoparticles, with a final drying step under N2 conditions. Using a variety of characterisation techniques, it was determined that nZVI particles were successfully synthesised via the reduction of iron (III) to iron (0) and stabilised by the presence of phenolic compounds in the extract. The removal of 20 mg/L nutrients from an aqueous solution carried out using the nZVIs resulted in nitrate removal of 92% (nZVI-GP), 88% (nZVI-BP), and 72% (nZVI-MP) within 5 min, whereas ∼98% phosphate was removed by all three nZVIs within 60 min. The aging effect was also tested. Aging the nZVIs for >20 days resulted in less efficient phosphate adsorption after exposure for 250 min; ∼70% phosphate removal was achieved using the nZVIs under these conditions. The mechanisms and pathways of nitrate reduction, including the adsorption of phosphate by nZVI were demonstrated, and discussed. Leachability tests of the phosphate-loaded nZVIs revealed that 10%, 28%, and 48% phosphate was released from the nZVI-GP, nZVI-BP, and nZVI-MP particles, respectively. Using waste fruit is, therefore, a viable and sustainable alternative to the traditional sodium borohydride method to produce nZVIs for environmental application.Research has shown that safety climate predicts safety outcomes in various occupational settings. PARP inhibitor One important component of safety climate is employees' perceived priorities of safety in an organisation relative to other operational demands (e.g. productivity or efficiency). The relationships between three dimensions of employee perceptions of safety priorities (company, supervisor, worker), employee safety behaviour and self-reported injury outcomes were examined in the current study. Survey data were collected from 858 field workers (a response rate of 89%) at a TV-cable installation company. Results showed that all three dimensions of employee perceptions of safety priorities had significant and unique positive relationships with employee safety behaviour. Furthermore, safety behaviour was a significant mediator of the relationship between the three types of perceived safety priorities and missed work days due to workplace injury. The results showed the value of addressing employee perceptions of safety priorities across organisational levels when trying to improve workplace safety and reduce costly injuries. Practitioner Summary The study examined relationships between the three different organisational levels of employee perceptions of safety priorities and employee safety behaviour and injury outcomes. The results demonstrated the value of addressing employee perceptions of safety priorities held by different levels of management as well as the worker level to improve workplace safety and reduce costly injuries. Abbreviations AIC Akaike Information Criterion; BIC Bayesian Information Criterion; CFA confirmatory factor analysis; CFI comparative fit index; CI confidence interval; NAICS the North American Industry Classification System; RMSEA root mean square errors of approximation; SB safety behavior; SD standard deviation; SE standard error; SIC the standard industrial class; SP safety priority.