Lentzdillard7624

83%; CIED-AI - 0.90% or Mittal score - 1.00%; P <0.001 - for all). We did not record any complication related to GCS. We analyzed cost-effectiveness of our GCS-based approach, which appeared to be financially beneficial (number needed to treat 149-200; difference of CIED infection treatment cost and GCSs price was 5093-26525 $).

We conclude that 1) use of GCS to reduce CIEDs infections is feasible and safe; 2) our multi-component prevention strategy involving the GCS application seems to significantly reduce rate of CIED infection and it is cost-effective.

We conclude that 1) use of GCS to reduce CIEDs infections is feasible and safe; 2) our multi-component prevention strategy involving the GCS application seems to significantly reduce rate of CIED infection and it is cost-effective.

Chronic kidney disease (CKD) is considered a risk factor for thromboembolicand bleeding events in patients with atrial fibrillation (AF).

We sought to assess predictors of clinical outcomes among AF patients with advanced CKD.

In a prospective cohort study we enrolled 180 consecutive AF patients with stage 4 CKD, defined as estimated glomerular filtration rate of 15-29 ml/min/1.73 m2, on vitamin K antagonists (n = 90) and non-vitamin K antagonists oral anticoagulants (n = 90). We assessed biomarkers, including growth differentiation factor-15, cystatin C, and high-sensitivity cardiac troponin T (cTnT-hs) and prothrombotic state parameters, including plasma fibrin clot permeability (Ks).

The median age of the patients was 71.0 (64.0-75.0) years (men 65.0%). The median estimated glomerular filtration rate was 24.0 (21.0-25.0) ml/min/1.73 m2, while median CHA2DS2-VASc score was 3.0 (2.0-4.0). Age (hazard ratio [HR] 1.11; 95% confidence interval [CI], 1.02-1.20) and decreased Ks (HR 0.55; 95% CI, 0.34-0.90) were associated with thromboembolic events (n = 18; 4.7% per year). Previous bleeding (HR 3.21; 95% CI, 1.22-8.45), growth differentiation factor-15 (HR 1.48; 95% CI, 1.29-1.69), cystatin C (HR 9.24; 95% CI, 2.15-39.67), and high-sensitivity cardiac troponin T (HR 1.30; 95% CI, 1.14-1.48) were independent predictors of major or clinically relevant non-major bleeding (n = 27; 7.1% per year). After adjustment for age and comorbidities, only cystatin C (HR 3.95; 95% CI, 1.08-14.37) predicted mortality (n = 25; 6.5% per year).

Novel biomarkers might be useful in risk stratification of thromboembolic and bleeding events in AF patients with stage 4 CKD receiving oral anticoagulants.

Novel biomarkers might be useful in risk stratification of thromboembolic and bleeding events in AF patients with stage 4 CKD receiving oral anticoagulants.Olfactory reference syndrome (ORS) is a rare psychiatric condition involving embarrassment and distress due to persistent mental preoccupation with the idea of emitting body odours foul and offensive enough to disturb others. This disorder is often accompanied by shame, embarrassment, significant distress, avoidance behavior, social phobia and social isolation. The patients may worry that they spread odours originating from their mouth, sweat, genital areas or the gut. This belief may lead the patients to misinterpret the behaviours of others, they may frequently smell themselves, shower and change clothing during the day. There are differences of opinion whether ORS should be considered as a delusional disorder or appear in under the rubric of obsessive-compulsive related disorders. One of the reasons that create this uncertainty is the variation in the response to different treatments. The treatment strategies generally include the use of antipsychotics, the antidepressants, they are preferentially used in combination. In this report we aimed to discuss the case of a 33-year old male patient whose first complaints had been diagnosed 14 years prior, with a diagnosis of OCD with low insight. Shortly after improvement of the OCD symptoms he developed ORS symptoms. We aimed here to discuss the place of ORS in the diagnostic systems with reference to this case.Even though effectiveness of clozapine on treatment resistant schizophrenia has been repeatedly demonstrated, it is also associated with many adverse effects including weight gain. Curiously, significant weight loss may occur in some patients. In this case report we discussed whether the observed weight loss could be a negative prognostic factor. The 56 year-old male patient, followed up with the diagnosis of schizophrenia for 20 years, had persistent positive and negative symptoms despite concurrent use of different antiypsychotics. He was diagnosed with treatment-resistant schizophrenia and started on clozapine with dose titration to 500 mg/day over 3 months. He was observed to have lost 17.6% of his initial body weight after 7 months of therapy. The Positive and Negative Syndrome Scale (PANSS) score of the patient did not change significantly. There are a few case reports in the literature on weight loss during clozapine therapy. Some proposed that the weight loss could be a sign of weak response to treatment which is based on the observation that the clinical response might be poor when there is a weight loss and no change in blood triglyceride levels is observed with the treatment. There is a need for more case-control and preclinical studies to explain the mechanisms underlying weight loss and weak response to clozapine therapy in schizophrenia.

The objective of this study was to develop a short scale that assesses the progress and recovery in addiction treatment with respect to all relevant areas, and to determine its validity and reliability.

After scanning the literature and consulting the experts, a pool of questions was. The pilot form was tested in 10 cases then a final 8-item scale was generated. Clinical sample of the study consisted of 307 alcohol/substance users who applied Turkish Green Crescent Outpatient Counselling Center for psychosocial treatment between March 2016 and March 2017. Non-clinical sample of the study is composed by 102 randomly chosen participants without a history of psychiatric disorder. The reliability of the Addiction Outcome Assessment Index (AOAI) questions was determined by computing the Cronbach's alpha coefficient, and the factor structure analysis was determined by varimax rotation. Analysis of the reliability of the change between sessions was conducted via Reliable Change Index-(RCI).

The Cronbach's alpha coefficient for the total Outcome Assessment Index (AOAI) was 0.80. Therapists' total correlation coefficient was 0.75. Explanatory Factor Analysis revealed 2 factors which explains 43.96% of the total variance. The difference between groups' AOAI-Turkish (BASI) mean score was statistically significant. Cut-off point was determined as 8.63. RCI was 3.5. AOAI's first session mean score was 14.92±5.63, the mean score decreased at the tenth session to 9.4±4.71.

The results showed that AOAI is a valid and reliable questionnaire that can be used to measure the progress of different dimensions of alcohol and substance use.

The results showed that AOAI is a valid and reliable questionnaire that can be used to measure the progress of different dimensions of alcohol and substance use.

There are many biopsychosocial determinants among factors that trigger criminal behavior. Social variables such as the number of friends involved in criminal activity and the amount of time spent with them, as well as psychological processes such as sentiments of entitlement, antisocial attitudes of the individual can influence the possibility of getting involved in acts of crime. The purpose of this study was to adapt the Measures of Criminal Attitudes and Associates (MCAA) to Turkish language and to test its reliability and validity of the Measurement of Criminal Attitudes and Associates (MCAA), adapted to the Turkish language (MCAA-TR).

The Turkish version of the scale was tested on 202 adult convicts and 208 undergraduate university students. In order to assess the concurrent validity of the MCAA-TR, the UPPS Impulsive Behavior Scale and Criminal Thinking Scale (MCAA) were given to participants.

Principal component analysis showed that the factor structure of the MCAA-TR was highly consistent with the original version of the scale. The Cronbach's Alpha internal consistency was 0.86 for the total scale and ranged from 0.68 to 0.82 for subscales. Results of discriminant function analysis showed a classification efficiency of 77.6%. Also, the total sub-dimension scores of the MCAA-TR showed significant correlation with the scores on the relevant sub-dimensions of the scales used to evaluate concurrent validity.

The MCAA-TR was found to be a valid and reliable tool for assessing crime related cognitions and attitudes.

The MCAA-TR was found to be a valid and reliable tool for assessing crime related cognitions and attitudes.

It has been emphasised recently that emotion regulation problems may be the core symptoms of attention deficit hyperactivity disorder (ADHD). read more In this study, we aimed to determine the incidence of alexithymia, the relationship between alexithymia and impulsiveness, the severity of ADHD, depression and anxiety semptoms in adult ADHD.

All participants were assessed with the Structured Clinical Interview For DSM IV Axis I Disorders (SCID-I); and completed the Toronto Alexithymia Scale (TAS), the Impulsive Behavior Scale (UPPS), the Beck Depression Inventory (BDI), the Beck Anxiety Inventory (BAI), Adult Attention Deficit and Hyperactivity Disorder Self Reporting Scale (ASRS) and the Wender Utah Rating Scale (WURS). The ADHD patients were also assessed with the Diagnostic Interview for ADHD (DIVA) for DSM-5 criteria.

The study included 101 ADHD patients with a mean age of 23.06 ± 4.24 years with 47.5% females, and 100 healthy control individuals with a mean age of 22.76 ± 5.68 years with 50% female participants. Alexithymia incidence was 41.5% in the ADHD group. The increase in the levels of impulsiveness, depression and anxiety correlated with the severity of ADHD symptoms; and impulsiveness predicted alexithymia in the ADHD group.

Alexithymia incidence was higher in the ADHD group. When ADHD and control participants were combined, alexithymic individuals was more associated with impulsivity with frequent display of anxiety symptoms.

Alexithymia incidence was higher in the ADHD group. When ADHD and control participants were combined, alexithymic individuals was more associated with impulsivity with frequent display of anxiety symptoms.

Trichotillomania (TTM) and Skin Picking Disorder (SPD) are psychiatric disorders characterized by chronic and compulsive pulling and picking to remove hair and skin. There are very few studies on the clinical and phenomenological differences of TTM and SPD. In this study we aimed to compare the clinical characteristics and comorbidities of patients diagnosed with TTM and SPD.

We enrolled 56 TTM and 113 SPD patients who were assessed with SCID-I for DSM-IV. In addition, we evaluated the DSM- 5 criteria for Obsessive and Compulsive Disorder spectrum. We also utilized sociodemographic form, the Clinical Global Impression Scale, the Beck Anxiety Inventory and the Beck Depression Inventory.

Although patients with TTM and SPD had many common clinical features and comorbidities, statistically significant differences were determined in the number of the pulling/picking sites (Z=- 7.084; p<0.001), the type of the outpatient clinics which they initially consulted (χ2=19.451; p<0.001), reasons for pulling/picking behavior (p<0.