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The obtained bit rate conditions only depend on the Lipschitz constant, the upper bounds of the delays and the dropout rate, and are independent of the bounded process noise.This paper investigates an anti-disturbance sliding mode control strategy for a rigid satellite system with external disturbance under the prescribed performance constraints. An interval observer is firstly introduced to generate the interval estimation of the attitude angular velocity. Then a finite time identical disturbance reconstruction strategy is developed by using the interval estimation. Based on the novel performance function and error transformation constraints, the attitude tracking error is converted into a new error system that guarantees the desired transient and steady-state responses for the tracking error. Then, by introducing the reconstructed disturbance, a finite time anti-disturbance controller is constructed with the backstepping method. The stability of the strategy is guaranteed by the Lyapunov stability method. Finally, simulation results demonstrate the effectiveness of the proposed approach.This paper presents new control designs and implementations of truck-trailer path following in forward and backward motions. The path following controls are designed in two modes, which are the controls with reference on the head-truck (RH-control) and with reference on the trailer (RT-control). Both modes aim to converge the distance and orientation errors of the head-truck as well as the trailer with respect to the desired path to zero. Using the designed controls, the asymptotic stabilities of the equilibrium points (i.e., error points equal to zeros) are analyzed using the Lyapunov method. The performances of RH-and RT-controls in controlling the truck-trailer are compared for forward and backward motions. The simulation results show that the RT-controls perform better than the RH-controls and the RT-controls can be applied for a curve-path following in both forward and backward directions. The experimental results of a prototype truck-trailer show the effectiveness of the proposed controls.In this paper, a novel fixed-time controller (FTC) strategy based on leader-follower mechanism and finite-time disturbance observer (FDO) is proposed for surface vehicles (SVs) formation suffering from complex unknowns. The excellent features of designed strategy are shown below (1) A fixed-time tracking control (FTTC) approach combining with integral sliding mode (ISM) technology is devised for a nominal leader SV such that fixed-time stability can be ensured; (2) To achieve formation efficiently, a fixed-time formation controller (FTFC) strategy incorporating with backstepping technology is proposed for coordinating follower SVs; (3) Considering complex disturbances in the entire formation system, finite-time disturbance observers (FDOs) are injected into the FTFC framework which in turn contributes to accurate formation control with fixed-time convergence. Finally, simulation results demonstrate remarkable performance of the proposed FDO-FTFC scheme.Background Overprescribing of opioids after surgery contributes to long-term abuse. this website Evaluating opioid prescription patterns and patient-reported opioid use offers an evidence-based method to identify potential overprescription. This quality improvement initiative aimed to reduce and standardize opioid prescriptions upon discharge from an ambulatory oncologic surgery center and evaluate the effect of this change on patients' subsequent opioid use and reported pain. Methods Between March 2018 and January 2019, consecutive opioid-naïve patients aged ≥ 18 years who underwent robotic or laparoscopic hysterectomy, radical prostatectomy, or partial nephrectomy, or total mastectomy with or without immediate reconstruction were surveyed 7-10 days postoperatively. Data collected in the pre- (n = 551) and post-standardization (n = 480) cohorts included perception of pain relief, opioids prescribed (verified by electronic medical record review) and consumed, and refills received. Results Pre-standardization, the median opioid prescription at discharge was 20 pills (interquartile range [IQR] 20-28) or 140 oral morphine milligram equivalents (MME) (IQR 100-150). Median opioid consumption was 2 pills (IQR 0-7) or 10 MME (IQR 0-40) among all services. Opioid prescriptions were later standardized to 7, 8, and 10 pills (35, 40, and 75 MME), in the gynecology, urology, and breast services, respectively. The change was not associated with an increase in reported pain. Refill requests increased postintervention across all surgeries from 4.4% to 7.7%, with the largest increase among patients who underwent breast surgery. Conclusion The number of opioid pills given at discharge to patients undergoing ambulatory or short-stay cancer surgery can safely be reduced.Buprenorphine and methadone are the two main opioid agonist treatments approved for opioid use disorder. Buprenorphine is a partial agonist of the mu opioid receptors, which has been merely available through sublingual form until now. In practice, the use of buprenorphine is smoother than that of methadone, and it induces reduced risks of overdose. However, sublingual buprenorphine also exposes to risks (e.g., withdrawal, misuse) and constraints (e.g., daily intake). Three new galenic formulations of prolonged-release buprenorphine (PRB) are being commercialized and should allow some improvements in patients' comfort and safety. This narrative review aims to describe the main technical features and efficacy and safety data of these PRBs, as well as patients' and professionals' expectancies and concerns, using data of the scientific literature and the regulatory texts. PRBs consist of one subcutaneous implant and two subcutaneous injection depots. Sixmo®/Probuphine® is a six-month-long implant which needs to be surgically placed and removed and is approved for subjects previously treated with a maximum daily dose of 8mg of sublingual buprenorphine, and can be used only for two successive periods of six months before the subject needs to be switched back to sublingual form. Sublocade® is a one-month-long depot formulation that is indicated in switch from sublingual buprenorphine, and which proposes only two dose schemes, i.e., 100 and 300mg monthly. Buvidal®/Brixadi® is a one-week- or one-month-long depot formulation with multiple dosages, which can be used in initiation or in switched from sublingual formulations. While opioid users report some concerns with a risk of coercive use of long-acting forms of buprenorphine, both users and professionals deem that these new specialties could be particularly appreciated in stabilized patients bothered with the daily intake of the treatments, or specific situations at risk of treatment dropout (e.g., following hospital discharge or prison release).

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