Larsenharmon8184
They also had lower VAS scores, higher life function score and total ASES scores, higher ASIA scores, higher ROM scores, lower VCAM-1 and ICAM-1 expression, lower complication rate, higher total effective rate, and higher patient satisfaction.
Massage combined with acupuncture can better improve the ROM of joints and daily living ability of patients with frozen shoulder complicated with cervical spondylosis.
Massage combined with acupuncture can better improve the ROM of joints and daily living ability of patients with frozen shoulder complicated with cervical spondylosis.
This study aimed to investigate the effect of care bundles on the postoperative pain, negative emotions, and self-care ability of patients with acute dacryocystitis.
We recruited 103 patients with acute dacryocystitis undergoing surgery in our hospital from July 2018 to October 2019 in this study. Among them, 55 patients received care bundles (the research group, RG) and the other 48 received conventional care (the control group, CG). The two groups were compared in response rate, Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS), and Exercise of Self-Care Agency Scale (ESCA) before and after nursing interventions, as well as postoperative Visual Analogue Scale (VAS), MOS 36-item short-form health survey (SF-36), and patient satisfaction rate.
After the care, the RG had a markedly higher response rate than the CG. No significant differences were found in SAS and SDS scores between the two groups before nursing care, and lower scores were found in the RG after the care. There was no significant difference in VAS scores before nursing care, and the RG showed higher scores than the CG after the care. There was no significant difference in self-care skills, self-care responsibility, self-concept, health knowledge, and self-care ability between the two groups before nursing care, but they all increased after the care. Markedly higher scores of SF-36 and a higher patient satisfaction rate were observed in the RG after the care.
Care bundles can enhance the self-care ability of patients with acute dacryocystitis after surgery, reduce pain intensity, relieve negative emotions, improve quality of life, and increase patient satisfaction with nursing care.
Care bundles can enhance the self-care ability of patients with acute dacryocystitis after surgery, reduce pain intensity, relieve negative emotions, improve quality of life, and increase patient satisfaction with nursing care.
To explore the effect of miR-21-5p on the MAP2K3 expressions and cellular apoptosis in the lung tissues of neonatal rats with hyperoxia-induced lung injuries (HILI).
Twenty Sprague-Dawley neonatal rats were assigned to the normal group, and 120 rats were used to create a HILI model and were divided into the following six groups of 20 rats each the model group, the miR-21-5p NC group, the miR-21-5p agomir group, the oe-NC group (MAP2K3 overexpression NC), the oe-MAP2K3 group, and the miR-21-5p agomir+oe-MAP2K3 group.
miR-21-5p can target MAP2K3. Compared with the normal rats, the rats with HILI had lower miR-21-5p expression levels and higher MAP2K3 expression levels in the lung tissues (both P<0.05). GSK'872 ic50 Unlike the normal group, the other groups all presented different degrees of lung injuries, lower Bcl-2 expression levels, higher cellular apoptosis rates, and higher expression levels of cleaved caspase-3, Bax, IL-6, and TNF-α (all P<0.05). Compared with the model and the miR-21-5p NC groups, the miR-21-5p agomir group had better results in terms of the aforementioned markers; compared with the oe-NC group, the oe-MAP2K3 group had worse results in terms of these markers (all P<0.05). Moreover, we found that the protective effects of miR-21-5p overexpression on the lung tissues of HILI rats can be partially blocked by MAP2K3 overexpression.
miR-21-5p can inhibit MAP2K3 expression and reduce cellular apoptosis in HILI, thereby exerting protective effects on neonatal rats with HILI.
miR-21-5p can inhibit MAP2K3 expression and reduce cellular apoptosis in HILI, thereby exerting protective effects on neonatal rats with HILI.
To observe the effects of baicalin capsules combined with α-lipoic acid on nerve conduction velocity, oxidative stress and inflammatory injury in patients with diabetic peripheral neuropathy.
A total of 96 patients with diabetic peripheral neuropathy who received treatment in our hospital were divided into the control group (CG) and the research group (SG) by a randomized double-blind method, with 48 cases in each group. In the CG, patients were treated with α-lipoic acid. In the SG, patients were treated with baicalin capsules combined with α-lipoic acid. The clinical efficacy, symptoms (neuropathic subjective symptom questionnaire (TSS) score), nerve conduction velocity, oxidative stress indicators (superoxide dismutase (SOD) and malondialdehyde (MDA)), inflammatory injury indicators (hs-C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor (TNF-α)) and adverse reactions were compared between the two groups.
The clinical efficacy in the SG was higher than that in the CG (P<0.05). Afopathy, this treatment can obviously relieve the clinical symptoms of patients, improve nerve conduction velocity, reduce oxidative stress and inflammatory injury, and it does not increase adverse reactions. link2 Therefore, it is worthy of promotion.
To investigate the effect of dexmedetomidine (DMED) on acute kidney injury in children undergoing congenital heart surgery (CHS) with cardiopulmonary bypass (CPB).
The children undergoing CHS with CPB were randomized to the control and the DMED groups. The children in the DMED group were injected with DMED (1 µg/kg) followed by DMED infusion (0.5 µg/kg/h) until 12 h after operation; the controls received normal saline. Markers were detected before operation (T0), 30 min after anesthesia induction (T1), and at 24 h, 48 h, and 72 h after operation (T2, T3, T4).
The heart rate and mean arterial pressure in the DMED group decreased at T1 and differed from controls at T1-T3 (all P<0.05). No intergroup differences were observed in the central venous pressure and caspase-3 level (all P>0.05). The DMED group had higher central venous pressure at T3 than at T0 (P<0.05). At T2-T4, the DMED group had lower percentages of TLR3
cells than the controls (all P<0.05). In the DMED group, the percentagesof TLR3
cells decreased with time; whereas in the control group, the percentage increased with time (all P<0.05). Compared with the controls, the DMED group had lower levels of NF-κB and TLR3 at T2-T4, lower levels of sCr, IL-1β, and TNF-α at T3-T4, and lower incidence of AKI at T3 (all P≤0.01).
DMED can reduce the risk of AKI in children undergoing CHS with CPB, which may be because DMED can inhibit TLR3/NF-κB signaling and its downstream inflammatory mediators.
DMED can reduce the risk of AKI in children undergoing CHS with CPB, which may be because DMED can inhibit TLR3/NF-κB signaling and its downstream inflammatory mediators.
This study was designed to probe into the influence of Orem's self-care model on the rehabilitation efficacy, disease cognition, self-care abilities and quality of life of acute coronary syndrome (ACS) patients after PCI.
A total of 148 ACS patients who underwent PCI in our hospital from October 2018 to October 2019 were recruited as the study cohort. Based on the nursing method each patient received, they were divided into two groups. Among the patients in the study cohort, 78 treated using Orem's self-care were placed into the research group (RG), and 70 treated using conventional nursing were placed in the control group (CG). Their postoperative complications, rehabilitation efficacy, disease cognition, negative emotions, self-care abilities, and quality of life were compared.
After the nursing intervention, in the RG, the postoperative complications, the time of D-to-B, the getting out of bed times and the hospitalization stays were significantly shorter than they were in the CG, and the disease cognition and self-care abilities scores were significantly higher. In addition, compared with the CG, the patients' SAS and SDS scores in the RG were dramatically lower and the quality of life scores and the nursing satisfaction were markedly higher.
Orem's self-care for ACS after PCI helps to reduce postoperative complications and improves patients' negative emotions and their rehabilitation efficacy, disease cognition, self-care abilities, quality of life, and nursing satisfaction.
Orem's self-care for ACS after PCI helps to reduce postoperative complications and improves patients' negative emotions and their rehabilitation efficacy, disease cognition, self-care abilities, quality of life, and nursing satisfaction.
This study aimed to investigate the effects of community-based rehabilitation (CBR) on the self-efficacy and quality of life in elderly patients with chronic obstructive pulmonary disease (COPD).
Eighty-one elderly patients with COPD admitted to our hospital were recruited as the study cohort and were randomly divided into a control group (n=41) and a study group (n=40). The control group underwent outpatient rehabilitative treatment, and the study group additionally underwent CBR. The treatment effects of the two groups at 1 month, 3 months, and 6 months of intervention were assessed using their pulmonary function and quality of life scores.
After completion of the CBR, the patients in the study group and the control group were scored using the CSES scale, which did not differ at 1 month of intervention, but the scores were higher in the study group than they were in the control group at 3 and 6 months of intervention (
< 0.05). The patients in the study group also scored higher on the WHOQOL-BREF scale than the control group (
< 0.05).
CBR improves the self-efficacy and quality of life in elderly patients with COPD.
CBR improves the self-efficacy and quality of life in elderly patients with COPD.
To investigate the effect of tracheal intubation and ProSeal laryngeal mask airway (PLMA) on hemodynamics, oxygen saturation, peak airway pressure and adverse events during anesthesia for thyroid surgery.
65 patients who underwent luminal thyroid surgery under general anesthesia were enrolled as the study subjects, and were divided into control group (30 patients, tracheal intubation) and experimental group (35 patients, PLMA) using random number table. The time to establishment of artificial airway and success rate, hemodynamics, oxygen saturation, peak airway pressure and adverse effects were observed in the two groups.
The SBP, DBP, and HR levels of patients in the experimental group were significantly lower than those of control group (P < 0.05), and there were no significant changes in SBP, DBP, and HR levels during the insertion and removal of the laryngeal mask, and the patients were hemodynamically stable. SpO
and Ppeak values remained stable at 5 min, 30 min, and 60 min after the start and the end of surgery in both groups, and showed no significant difference between the two groups (P > 0.05). link3 A surgical airway was quickly established in both groups, and the time to airway establishment was shorter in the experimental group than in the control group. The incidence of adverse reactions during extubation was lower in the experimental group than in the control group, and the incidence of hoarseness, choking and cough differed significantly between the two groups (P < 0.05), and the adverse reactions in both groups were relieved or disappeared 24 h after the operation.
With LMPA, patients are more hemodynamically stable during insertion and removal of the mask, have a lower incidence of adverse events, and experience less throat irritation, with safety.
With LMPA, patients are more hemodynamically stable during insertion and removal of the mask, have a lower incidence of adverse events, and experience less throat irritation, with safety.
