Kuskakhtar1594
collaborate on a future individual participant data meta-analysis.
CRD42020173242.
CRD42020173242.
We examine the association between vitamin B
level and risk for acute kidney injury (AKI) in patients undergoing living donor liver transplantation (LDLT).
Retrospective observational cohort study.
University hospital, from January 2009 to December 2018.
A total of 591 patients who underwent elective LDLT were analysed in this study. Those with a preoperative history of kidney dysfunction, vitamin B
supplementation due to alcoholism, low vitamin B
(<200 pg/mL) or missing laboratory data were excluded.
The population was classified into AKI and non-AKI groups according to Kidney Disease Improving Global Outcomes (KDIGO) criteria, and associations between perioperative factors and AKI were analysed. After 11 propensity score (PS) matching, the association between high vitamin B
(>900 pg/mL) and postoperative AKI was evaluated.
Preoperative vitamin B
was higher in the AKI group. check details Potentially significant perioperative factors from univariate analyses were entered into multivariate analyses, including preoperative factors (vitamin B
, diabetes), intraoperative factors (hourly urine output) and donor graft fatty change in LDLT patients. PS matching analyses with adjustment using PS revealed that high serum vitamin B
(>900 pg/mL) was associated with risk for AKI, and the risk was 2.8-fold higher in patients with high vitamin B
than in those with normal vitamin B
. Higher vitamin B
was also related to a higher AKI stage. In addition, inflammatory factors (C reactive protein, white blood cells and albumin) were associated with vitamin B
level.
Our study may improve the accuracy of predicting postoperative AKI by introducing preoperative vitamin B
into risk assessments for patients undergoing LDLT.
Our study may improve the accuracy of predicting postoperative AKI by introducing preoperative vitamin B12 into risk assessments for patients undergoing LDLT.
Obesity increases the risk of comorbidities and diabetes-related complications and, consequently, efforts to prevent and reduce excess weight in people with type 1 diabetes are essential. The aim of this systematic review and network meta-analysis is to assess the effect of adjunctive glucose-lowering drugs on body weight and other important health outcomes in people with type 1 diabetes.
This systematic review and network meta-analysis will include randomised controlled trials (RCTs) evaluating the use of adjunctive glucose-lowering drugs for treatment of people with type 1 diabetes. MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, ClinicalTrials.gov and WHO International Clinical Trials Registry Platform will be searched from inception to present. Key eligibility criteria include RCT study design; adult participants with type 1 diabetes; treatment with a glucose-lowering drug for ≥24 weeks; and comparison of the intervention to placebo, usual carelication and conference presentation.
CRD42020158676.
CRD42020158676.
Male involvement has been reported to improve maternal and child health (MCH) outcomes. However, most studies in low-income and middle-income countries have reported low participation of men in MCH-related programmes. While there is a growing interest in the involvement of men in MCH, little is known on how male involvement can be effectively promoted in settings where entrenched unequal gender roles, norms and relations constrain women from effectively inviting men to participate in MCH.
This paper reports participatory action research (PAR) aimed to promote male participation in pregnancy and childbirth in Iringa Region, Tanzania. As part of the Innovating for Maternal and Child Health in Africa project, PAR was conducted in 20 villages in two rural districts in Tanzania. Men and women were engaged separately to identify barriers to male involvement in antenatal care and during delivery; and then they were facilitated to design strategies to promote male participation in their communities. Along with thg the implementation of these strategies.
The present study was designed to demonstrate the relationships among shift work, hair cortisol concentration (HCC) and sleep disorders.
A cross-sectional study.
Three petroleum administrations in Karamay city of Xinjiang, China.
435 individuals including 164 males and 271 females participated in the research.
Information on shift work was collected by a self-administered questionnaire. HCC was determined using an automatic radioimmunoassay instrument. Sleep quality was measured on the Pittsburgh Sleep Quality Index scale.
Shiftwork was associated with an increased prevalence of sleep disorders compared with the fixed day shift (two shifts OR 3.11, 95% CI 1.57 to 6.19; three shifts OR 2.87, 95% CI 1.38 to 5.98; four shifts OR 2.22, 95% CI 1.17 to 4.18; others OR 3.88, 95% CI= 1.36 to 11.08). Workers with different shift patterns had higher HCC levels than day workers ((fixed day shift geometric mean±geometric SD=2.33±1.65; two shifts 3.76±1.47; three shifts 3.15±1.64; four shifts 3.81±1.55; othersy marker of shiftwork circadian disruption to early detection and management of sleep disorders.
The objective of the study is to compare body mass index (BMI), systolic/diastolic blood pressure (SBP/DBP) and serum total cholesterol levels between dementia cases and controls at multiple time intervals prior to dementia onset, and to test time interval as a modifying factor for these associations.
Case-control study.
Six European electronic health records databases.
291 780 cases at the date of first-recorded dementia diagnosis, compared with 29 170 549 controls randomly selected from the same databases, age matched and sex matched at this index date.
The following measures were extracted whenever recorded within each dataset BMI (kg/m
), SBP and DBP (mm Hg) and serum total cholesterol (mmol/L). Levels for each of these variables were defined within six 2-year time intervals over the 12 years prior to the index date.
Case-control differences in exposures of interest were modelled for each time period and adjusted for demographic and clinical factors (ischaemic/unspecified stroke, type 2 diabetes mellitus, acute myocardial infarction, hypertension diagnosis, antihypertensive medication, cholesterol-lowering medication).
