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In the end, a numerical example is applied to show the effectiveness of the theoretical method.In this article, the intrinsic properties of hyperspectral imagery (HSI) are analyzed, and two principles for spectral-spatial feature extraction of HSI are built, including the foundation of pixel-level HSI classification and the definition of spatial information. Based on the two principles, scaled dot-product central attention (SDPCA) tailored for HSI is designed to extract spectral-spatial information from a central pixel (i.e., a query pixel to be classified) and pixels that are similar to the central pixel on an HSI patch. Then, employed with the HSI-tailored SDPCA module, a central attention network (CAN) is proposed by combining HSI-tailored dense connections of the features of the hidden layers and the spectral information of the query pixel. MiniCAN as a simplified version of CAN is also investigated. Superior classification performance of CAN and miniCAN on three datasets of different scenarios demonstrates their effectiveness and benefits compared with state-of-the-art methods.To solve the user data sparsity problem, which is the main issue in generating user preference prediction, cross-domain recommender systems transfer knowledge from one source domain with dense data to assist recommendation tasks in the target domain with sparse data. However, data are usually sparsely scattered in multiple possible source domains, and in each domain (source/target) the data may be heterogeneous, thus it is difficult for existing cross-domain recommender systems to find one source domain with dense data from multiple domains. In this way, they fail to deal with data sparsity problems in the target domain and cannot provide an accurate recommendation. In this article, we propose a novel multidomain recommender system (called HMRec) to deal with two challenging issues 1) how to exploit valuable information from multiple source domains when no single source domain is sufficient and 2) how to ensure positive transfer from heterogeneous data in source domains with different feature spaces. In HMRec, domain-shared and domain-specific features are extracted to enable the knowledge transfer between multiple heterogeneous source and target domains. To ensure positive transfer, the domain-shared subspaces from multiple domains are maximally matched by a multiclass domain discriminator in an adversarial learning process. The recommendation in the target domain is completed by a matrix factorization module with aligned latent features from both the user and the item side. Extensive experiments on four cross-domain recommendation tasks with real-world datasets demonstrate that HMRec can effectively transfer knowledge from multiple heterogeneous domains collaboratively to increase the rating prediction accuracy in the target domain and significantly outperforms six state-of-the-art non-transfer or cross-domain baselines.Segmentation-based methods have achieved great success for arbitrary shape text detection. https://www.selleckchem.com/products/pf-2545920.html However, separating neighboring text instances is still one of the most challenging problems due to the complexity of texts in scene images. In this article, we propose an innovative kernel proposal network (dubbed KPN) for arbitrary shape text detection. The proposed KPN can separate neighboring text instances by classifying different texts into instance-independent feature maps, meanwhile avoiding the complex aggregation process existing in segmentation-based arbitrary shape text detection methods. To be concrete, our KPN will predict a Gaussian center map for each text image, which will be used to extract a series of candidate kernel proposals (i.e., dynamic convolution kernel) from the embedding feature maps according to their corresponding keypoint positions. To enforce the independence between kernel proposals, we propose a novel orthogonal learning loss (OLL) via orthogonal constraints. Specifically, our kernel proposals contain important self-information learned by network and location information by position embedding. Finally, kernel proposals will individually convolve all embedding feature maps for generating individual embedded maps of text instances. In this way, our KPN can effectively separate neighboring text instances and improve the robustness against unclear boundaries. To the best of our knowledge, our work is the first to introduce the dynamic convolution kernel strategy to efficiently and effectively tackle the adhesion problem of neighboring text instances in text detection. Experimental results on challenging datasets verify the impressive performance and efficiency of our method. The code and model are available at https//github.com/GXYM/KPN.AdaBelief, one of the current best optimizers, demonstrates superior generalization ability over the popular Adam algorithm by viewing the exponential moving average of observed gradients. AdaBelief is theoretically appealing in which it has a data-dependent O(√T) regret bound when objective functions are convex, where T is a time horizon. It remains, however, an open problem whether the convergence rate can be further improved without sacrificing its generalization ability. To this end, we make the first attempt in this work and design a novel optimization algorithm called FastAdaBelief that aims to exploit its strong convexity in order to achieve an even faster convergence rate. In particular, by adjusting the step size that better considers strong convexity and prevents fluctuation, our proposed FastAdaBelief demonstrates excellent generalization ability and superior convergence. As an important theoretical contribution, we prove that FastAdaBelief attains a data-dependent O(log T) regret bound, which is substantially lower than AdaBelief in strongly convex cases. On the empirical side, we validate our theoretical analysis with extensive experiments in scenarios of strong convexity and nonconvexity using three popular baseline models. Experimental results are very encouraging FastAdaBelief converges the quickest in comparison to all mainstream algorithms while maintaining an excellent generalization ability, in cases of both strong convexity or nonconvexity. FastAdaBelief is, thus, posited as a new benchmark model for the research community.Robot-assisted minimally invasive surgeries (RAMIS) have many benefits. A disadvantage, however, is the lack of haptic feedback. Haptic feedback is comprised of kinesthetic and tactile information, and we use both to form stiffness perception. Applying both kinesthetic and tactile feedback can enable more precise feedback than kinesthetic feedback alone. However, during remote surgeries, haptic noises and variations can be present. Therefore, toward designing haptic feedback for RAMIS, it is important to understand the effect of haptic manipulations on stiffness perception. We assessed the effect of two manipulations using stiffness discrimination tasks in which participants received force feedback and artificial skin stretch. In Experiment 1, we added sinusoidal noise to the artificial tactile signal, and found that the noise did not affect participants' stiffness perception or uncertainty. In Experiment 2, we varied either the kinesthetic or the artificial tactile information between consecutive interactions with an object. We found that the both forms of variability did not affect stiffness perception, but kinesthetic variability increased participants' uncertainty. We show that haptic feedback, comprised of force feedback and artificial skin stretch, provides robust haptic information even in the presence of noise and variability, and hence can potentially be both beneficial and viable in RAMIS.We present the results of a double-blind phase 2b randomized control trial that used a custom built virtual reality environment for the cognitive rehabilitation of stroke survivors. A stroke causes damage to the brain and problem solving, memory and task sequencing are commonly affected. The brain can recover to some extent, however, and stroke patients have to relearn how to carry out activities of daily living. We have created an application called VIRTUE to enable such activities to be practiced using immersive virtual reality. Gamification techniques enhance the motivation of patients such as by making the level of difficulty of a task increase over time. The design and implementation of VIRTUE is described together with the results of the trial conducted within the Stroke Unit of a large hospital. We report on the safety and acceptability of VIRTUE. We have also observed particular benefits of VR treatment for stroke survivors that experienced more severe cognitive impairment, and an encouraging reduction in time spent in the hospital for all patients that received the VR treatment.Transcutaneous electrical stimulation has been applied in tremor suppression applications. Out-of-phase stimulation strategies applied above or below motor threshold result in a significant attenuation of pathological tremor. For stimulation to be properly timed, the varying phase relationship between agonist-antagonist muscle activity during tremor needs to be accurately estimated in real-time. Here we propose an online tremor phase and frequency tracking technique for the customized control of electrical stimulation, based on a phase-locked loop (PLL) system applied to the estimated neural drive to muscles. Surface electromyography signals were recorded from the wrist extensor and flexor muscle groups of 13 essential tremor patients during postural tremor. The EMG signals were pre-processed and decomposed online and offline via the convolution kernel compensation algorithm to discriminate motor unit spike trains. The summation of motor unit spike trains detected for each muscle was bandpass filtered betweene tremor-suppression neuroprostheses.While the loss of sensorimotor and autonomic function often occurs due to multiple trauma and pathologies, spinal cord injury is one of the few traumatic pathologies that severely affects multiple organ systems both upstream and downstream of the injury. Current standard of care therapies primarily maintains health and avoids secondary complications. They do not address the underlying neurological condition. Multiple modalities including spinal neuromodulation have shown promise as potential therapies. The objective of this study was to demonstrate the impact of activity-based neurorehabilitation in presence of epidural spinal stimulation to enable simultaneous global recovery of sensorimotor and autonomic functions in patients with complete motor paralysis due to spinal cord injury. These data are unique in that it quantifies simultaneously changes multiple organ systems within only 2 months of intense activity-based neurorehabilitation when also delivering epidural stimulation consisting of sub-motor threshold stimulation over a period of 12-16 hours/day to enable 'self-training' in 10 patients. Finally, these studies were done in a traditional neurorehabilitation clinical in India using off-the-shelf electrode arrays and pulse generators, thus demonstrating the feasibility of this approach in simultaneously enabling recoveries of multiple physiological organ systems after chronic paralysis and the ability to perform these procedures in a standard, well-controlled clinical environment.

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