Kendallholmgaard3642

There were more family caregivers in the control group who expressed a high level of stress and anxiety, and they also requested more social and health services compared with caregivers whose family member received telerehab.

Family caregivers are an essential component of recovery after hip fracture by providing emotional and physical support. However, future clinical interventions should evaluate person-centered interventions to mitigate possible stress and anxiety experienced by family caregivers.

Family caregivers' perspectives are necessary in the co-design of management strategies for older adults after hip fracture.

Family caregivers' perspectives are necessary in the co-design of management strategies for older adults after hip fracture.

Various core materials with different shades affect the final color of high-translucency monolithic zirconia restorations. The blue core shows the greatest color difference in final zirconia restorations followed by metal, A3 dentin-shade resin core, and white core.

The purpose of this study was to evaluate the masking ability of high-translucency monolithic zirconia for various core materials. A computer-aided design-computer-aided manufacturing system was used to design a zirconia disc with a diameter of 10 mm and a thickness of 1.0 mm. Four groups of cores (n=15 each) were fabricated with blue-colored dual-cure resin, white-colored dual-cure resin, A3 dentin-shade composite resin, and titanium block with 10-mm diameter and 5-mm thickness.Dual-cure, self-adhesive resin cement discs with a thickness of 25.0 ± 0.02 μm were fabricated. The color was measured using a handheld spectrophotometer. Color measurements of all specimens were performed on a white background. To assess the masking ability of zirconitermined. To enhance the optical connection between the specimens, distilled water was applied between each layer during each measurement.The results showed that the value of ΔE was highest for the blue core followed by metal, A3 dentin-shade resin core, and white-resin core. No significant differences were observed between the metal core and the A3 dentin-shade resin core or between the A3 dentin-shade resin core and the white core. The blue core had the significantly highest ΔE value based on Tukey's honest significant difference test.Different core materials affect the final color of high-translucency monolithic zirconia restorations. Thus, our study showed that the final color of high-translucency monolithic zirconia restorations could be affected by the type of core material used.

Evidence suggests altered pronociceptive and antinociceptive mechanisms in many chronic pain conditions. Knowledge about these mechanisms in nonspecific chronic neck pain (NSNP) would improve understanding of the causes and the design of more effective treatments. Pressure pain threshold (PPT) is often used to assess presence of altered nociceptive processing in NSNP; however, its usefulness to detect this is yet to be established. The purpose of this study was to determine the functional status of temporal summation of second pain (TSSP) and conditioned pain modulation (CPM) in NSNP and to characterize the association of both measures with PPT and clinical features of NSNP.

Thirty-two participants with NSNP (mean [SD] age=44 [11] years; 27 female) and 32 age- and sex-matched healthy controls were recruited. Raphin1 cell line TSSP was assessed using an electrical stimulus at the dorsum of the hand, and CPM was evaluated with the Cold Pressor Test. PPT was assessed bilaterally at the neck and tibialis anterior muscles.

Parpreted as evidence of unaltered central pain-related processing.

It has been a long-standing clinical concern that haemodialysis (HD) patients on afternoon shifts (ASs) are more prone to protein-energy wasting (PEW) than those on morning shifts (MSs), as their dialysis scheme and post-dialysis symptoms may interfere with meal intake. We evaluated the effect of time of day of HD on the evolution of body composition changes and PEW surrogates.

We conducted a retrospective study among 9.963 incident HD patients treated in NephroCare centres (2011-16); data were routinely collected in the European Clinical Database. The course of multi-frequency bioimpedance determined lean and fat tissue indices (LTI and FTI) between patients in MSs/ASs over 2 years were compared with linear mixed models. Secondary PEW indicators were body mass index, albumin, creatinine index and normalized protein catabolic rate. Models included fixed (age, sex, vascular access and diabetes mellitus) and random effects (country and patient).

Mean baseline LTI and FTI were comparable between MSs (LTI 12.5 ± 2.9 kg/m2 and FTI 13.7 ± 6.0 kg/m2) and ASs (LTI 12.4 ± 2.9 kg/m2 and FTI 13.2 ± 6.1 kg/m2). During follow-up, LTI decreased and FTI increased similarly, with a mean absolute change (baseline to 24 months) of -0.3 kg/m2 for LTI and +1.0 kg/m2 for FTI. The course of these malnutrition indicators did not differ between dialysis shifts (P for interaction ≥0.10). We also did not observe differences between groups for secondary PEW indicators.

This study suggests that a dialysis shift in the morning or in the afternoon does not impact the long-term nutritional status of HD patients. Regardless of time of day of HD, patients progressively lose muscle mass and increase body fat.

This study suggests that a dialysis shift in the morning or in the afternoon does not impact the long-term nutritional status of HD patients. Regardless of time of day of HD, patients progressively lose muscle mass and increase body fat.

Obesity and hypogonadism additively contribute to frailty in older men; however, appropriate treatment remains controversial.

Determine whether testosterone replacement augments the effect of lifestyle therapy on physical function in older men with obesity and hypogonadism.

Randomized, double-blind, placebo-controlled trial.

VA Medical Center.

83 older (age ≥65 years) men with obesity (body mass index ≥30 kg/m2) and persistently low am testosterone (<10.4 nmol/L) associated with frailty.

Participants were randomized to lifestyle therapy (weight management and exercise training) plus either testosterone (LT+Test) or placebo (LT+Pbo) for 6 months.

Primary outcome was change in Physical Performance Test (PPT) score. Secondary outcomes included other frailty measures, body composition, hip bone mineral density (BMD), physical functions, hematocrit, prostate specific antigen (PSA), and sex hormones.

PPT score increased similarly in LT+Test and LT+Pbo group (17% vs. 16%; P = 0.58). VO2peak increased more in LT+Test than LT+Pbo (23% vs.