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Streptococcus pneumonia is a cause of serious mortality and morbidity, especially among small children. However, currently, it causes lower rates of invasive infections due to successful vaccination programs Case. We report an exceptional case of a 6-month-old child with meningoencephalitis caused by Streptococcus pneumonia despite the administration of two doses of pneumococcal conjugate vaccine (PCV). Meningitis progressed rapidly and led to widespread damage in parenchymal brain tissue with the emergence of fulminant meningoencephalitis. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed widespread brain lesions, suggesting extensive parenchymal injury.

Such diffuse white matter lesions among pediatric patients with Streptococcus pneumonia meningoencephalitis despite two doses of PCV have not been reported previously.

Such diffuse white matter lesions among pediatric patients with Streptococcus pneumonia meningoencephalitis despite two doses of PCV have not been reported previously.

Visual problems, cerebral visual impairment, refractive errors and strabismus are commonly found in preterm infants in long-term follow-ups. The aim of this study was to determine the factors that lead to the development of amblyogenic risk factors, such as high refractive errors, anisometropia and strabismus, in the long-term evaluation of preterm infants.

We retrospectively evaluated children who were screened for retinopathy of prematurity (ROP) and who had a 3rd year ophthalmologic examination. The impacts of sex, gestational age (GA), birth weight (BW), BW for GA, being small for gestational age (SGA), being appropriate for gestational age (AGA), multiple pregnancies and the results of ROP screening on refractive errors and the development of strabismus were evaluated by logistic regression analysis. The SGA and AGA groups were compared in terms of refractive errors and presence of strabismus.

Six hundred and eight children, including 317 (52.1%) males and 291 (47.9%) females, were included in the study. The mean GA was 31 ± 3 weeks (24-36), and the mean BW was 1505 ± 435 g (600-2460). The number of SGA-born children was 101 (16.6%). Manifest deviation was detected in 42 (5.6%) children, and optical correction was required in 101 (16.6%) children. Being an SGA infant and multiple pregnancies were risk factors for refractive errors requiring optical correction, and hyperopia (≥3.00 D) was found to be a risk factor for the development of strabismus in the multivariate regression analysis. Additionally, the SGA group was at high risk for strabismus, hyperopia, high astigmatism and the need for optical correction.

We concluded that SGA seems to be associated with an increased risk of strabismus and a high refractive error. It should be taken into consideration during follow-up examinations of SGA infants.

We concluded that SGA seems to be associated with an increased risk of strabismus and a high refractive error. It should be taken into consideration during follow-up examinations of SGA infants.

Hypertension is a progressive disease with a prehypertensive phase. The most important feature of this period is the abnormal cardiovascular reactivity to various stressors. In our study, we focused on normotensive children of hypertensive parents, a special group that is at risk.

We evaluated the children according to age, studying whether they showed higher cardiovascular reactivity at different steps of an exercise test and during a recovery period than their counterparts with a negative history. A total of 110 normotensive children who were between the ages of 6 and 18 years were enrolled into the study. Sixty-two children whose parent(s) had a history of hypertension formed the study group while 48 without this history formed the control group. An exercise test was performed according to the Bruce protocol. Maximal systolic blood pressures and systolic blood pressures were taken while the participants were at rest; during phases 2 and 3; and also in the first, third, and sixth minutes of the recovery period.

Measurements were significantly higher in the study group (p < 0.05). In the group of children between the ages of 6 and 10 years, cardiovascular responses were similar. Children older than 10 years, however, had significantly higher blood pressure levels than those in the control group. The children who were at risk of hypertension showed more exaggerated cardiovascular responses during the exercise test and recovery period. This response was particularly evident for those children 10 years of age and older.

Our study indicates that treadmill exercise is a safe and effective investigational method which can be used to identify children who are at risk for development of hypertension before this condition becomes clinically evident.

Our study indicates that treadmill exercise is a safe and effective investigational method which can be used to identify children who are at risk for development of hypertension before this condition becomes clinically evident.

The negative effect of genital and extragenital warts on adult patient quality of life (QoL) is well known; however, the literature lacks data on the effect of extragenital warts on Turkish pediatric patient QoL. The aim of this study was to determine the effect of extragenital warts that persist for ≥6 months on Turkish pediatric patient QoL, as well as to determine the relationship between patient demographic and clinical characteristics, and QoL.

The Pediatric Quality of Life Inventory Version 4.0 (PedsQLTM 4.0) was administered to 85 children and their parents (patient group), and 85 age- and gender-matched children without any skin disease and their parents (control group). Children`s Dermatology Life Quality Index (CDLQI) was administered to the patients. Higher CDLQI and PedsQLTM are indicative of lower QoL.

Median wart duration and median age at the time of wart onset was 12 months (range 6-84) and 10 years (range 1-16), respectively. In the patient group mean (±Standard deviation [SD]) CDLQI score was 5.20 ± 5.97, and warts had the greatest negative effect on CDLQI symptoms and feelings scores. Mean (±SD) PedsQLTM total score was higher in the affected patients than that for the controls (23.42 ± 12.33 versus 15.81 ± 7.37, P < 0.001), and school, social and emotional functionality subscales exhibited the greatest differences between these groups. Mean (±SD) PedsQLTM total score for the patients` parents was higher than that for the controls` parents (25.94 ± 12.49 versus 17.81 ± 6.87, P < 0.001), and social and emotional functionality subscales exhibited the greatest difference between these groups.

The findings show that Turkish children with warts that persist for ≥6 months had lower QoL than the controls.

The findings show that Turkish children with warts that persist for ≥6 months had lower QoL than the controls.

Idiopathic facial paralysis or Bell`s palsy is the most common type of peripheral facial paralysis. read more Children with Bell`s palsy is an uneasy situation for the family and physician with questions about the etiology, treatment options and the healing process. Here, we aimed to compare the epidemiologic features and prognostic factors of patients with Bell`s palsy aged < 18 years.

Records of patients with Bell`s palsy who were admitted to our clinic between January 2008 and December 2017 were evaluated.

Forty-seven patients with Bell`s palsy were included to this study. The patients` ages varied between 7 and 17 (14.7±2.5) years. At the end of at least 6 months of follow-up, 32 (68.1%) of the patients presented with House Brackmann (HB) grade 1 facial paralysis, while 12 (25.5%) of them had grade 2 and 3 (6.4%) of them had grade 3 facial paralysis. Mean neutrophil-to-lymphocyte ratio (NLR) in patients with advanced grades (grade 4, 5, 6) was higher, compared to that of patients with grade 2 and 3 (4.10 ± 1.06 vs 1.34 ± 1.02 (p < 0.001).

In our study, the response rate to treatment was high. In differential diagnosis, congenital anomalies, malignancy, trauma, middle ear infection and surgery should be considered. In addition, NLR at admission can be considered as a prognostic factor.

In our study, the response rate to treatment was high. In differential diagnosis, congenital anomalies, malignancy, trauma, middle ear infection and surgery should be considered. In addition, NLR at admission can be considered as a prognostic factor.

Acne vulgaris causes profound negative physical, psychological and social effects on self-image and a negative impact on the quality of life. link2 Most research so far has been limited to adults, and little is known about the emotion regulation, medication adherence, clinical dimensions and psychopathology symptoms in young people with acne vulgaris.

A cross-sectional analytical study was conducted in a center in western Turkey. Ninety-six adolescents with acne vulgaris and 100 controls participated in the study. All participants completed self-report questionnaires including the Strength and Difficulties Questionnaire (SDQ), Difficulties in emotion regulation scale (DERS) and Morisky medication adherence scale-8 (MMAS-8). Acne severity was assessed with The Global Acne Grading Score (GAGS).

Acne vulgaris patients showed poorer SDQ and DERS scores reflecting the emotional regulation problems and psychopathological symptoms compared to healthy controls. The percentages of high, medium and low adherence were 6reatment efficacy. It is important to include emotional regulation interventions to improve medication adherence and quality of health care in young acne patients.

Despite several treatment modalities being described for pelvic floor dyssynergia-type constipation, the clinical evaluation of interferential current therapy (IFC) has not been examined. We aimed to examine the clinical effects of IFC therapy in the treatment of children with pelvic floor dyssynergia-type constipation.

Between May 2018 and July 2019, this randomized controlled study included sixty-two children (46 boys and 16 girls) with pelvic floor dyssynergia-type constipation; their ages ranged between 7 and 15 years. The children were randomly divided into either the IFC group (n = 31) who received an active IFC therapy to stimulate the pelvic floor and external anal sphincter muscles, three times per week for four successive weeks, or the control group (n = 31) who received sham IFC stimulation. Stool-incontinence frequency per week, stool type, pelvic floor excursion, and myogenic activity of external anal sphincter were evaluated at the baseline, post-treatment, and three months after treatment ttment could improve the main features of pelvic floor dyssynergia-type constipation.

Investigating life-stage factors associated with overweight may be useful in the prevention of excessive BMI increase. The main aim of this study was to investigate the influence of the route of delivery, birth weight and overweight onset on overweight severity in a sample of overweight adolescents followed at a Pediatric Obesity Clinic.

Clinical data from 412 adolescents with overweight (BMI ≥ p85), aged 10-18 were retrospectively collected and analyzed.

Adolescents born by cesarean section (CS) showed a lower age of overweight onset, compared to other methods of delivery (d= 0.33, p= .009). link3 Birth weight was positively associated with BMI z-score (r=.164, p= 002) and waist circumference (WC) (r=.191, p=.001). The overweight onset was negatively associated with BMI z-score (r= -.277, p < .001), WC (r= -.270, p < .001) and body fat mass (r= -.199, p=.001). Overweight duration was the best predictor of BMI z-score, explaining in 75% its variation (F=1,317)=26.94, p < .001), which increased to 99% when birth weight was included in the model (F(2,316)=18.

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