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While their specific roles and duties have changed to include naloxone administration to reverse opioid overdoses and providing referrals, officers felt that this was just part of their job in responding to the needs of the community. Officers reported that they have learned how to use (99%) and carry naloxone (87%) to reverse opioid related overdoses. The majority (92%) reported providing referrals (e.g., treatment and harm reduction resources) to individuals who misuse opioids. Conclusions The opioid epidemic has changed the roles of law enforcement officers, including providing naloxone to reverse overdoses and referrals for treatment. Future research should continue to explore how substance misuse in the community changes the roles of law enforcement officers and how to best train and support officers as their roles evolve in response to these changes.Prediction equations have been considered an accurate method for estimating resting metabolic rate (RMR) across multiple populations, but their accuracy for college-aged individuals not on an athletics team remains to be determined. Sixty-two college-aged (18 - 30 yrs.) males (n = 31) and females (n = 31) had their RMR measured (RMRm), using indirect calorimetry, and body composition assessed via air-displacement plethysmography. The World Health Organization (WHO), Mifflin-St Jeor (Mifflin), Harris-Benedict (HB), Cunningham, and Nelson equations were used to estimate RMR. No difference was observed between the Cunningham and RMRm regardless of sex (p≥0.05). All other prediction equations estimated a significantly lower RMR for males (p less then 0.05). The Mifflin and Nelson equations predicted an RMR that was significantly lower than RMRm for females (p less then 0.05). When compared to RMRm, no difference was detected for females using the WHO, HB, or Cunningham (p≥0.05). Only the Nelson equation predicted an RMR that was outside of the clinically acceptable range (±10% of RMRm) regardless of sex. The Cunningham, WHO, and HB equations can accurately predict RMR for college-aged males and females. RMR prediction equations used in this study are less accurate for those with greater RMRs. Key Findings • For adults 18-30 years old that are not on an athletics team, the Cunningham equation can accurately predict RMR. • The Nelson equation should not be used to predict RMR for this population. • There is a systemic bias for RMR prediction equations to underestimate higher measured RMR values.The mammalian motor cortex is topographically organized into representations of discrete body parts (motor maps). Studies in adult rats using long-duration intracortical microstimulation (LD-ICMS) reveal that forelimb motor cortex is functionally organized into several spatially distinct areas encoding complex, multijoint movement sequences elevate, advance, grasp, and retract. The topographical arrangement of complex movements during development and the influence of skilled learning are unknown. Here, we determined the emergence and topography of complex forelimb movement representations in rats between postnatal days (PND) 13 and 60. We further investigated the expression of the maps for complex movements under conditions of reduced cortical inhibition and whether skilled forelimb motor training could alter their developing topography. We report that simple forelimb movements are first evoked at PND 25 and are confined to the caudal forelimb area (CFA), whereas complex movements first reliably appear at PND However, the development and plasticity of those complex movements is completely unknown. In this paper, the emergence and topography of complex movement representation, as well as their plasticity during development, is detailed.In order to understand HIV-positive Malawian adults' experiences with hypertension management, we conducted qualitative interviews with 30 hypertensive adults who were also taking antiretroviral therapy. These interviews regarding hypertension management behaviours and beliefs were audio-recorded, transcribed, translated into English, and coded in Atlas.ti. Despite acknowledging the dangers of hypertension and the benefits of medication, many respondents missed their antihypertensive medication. Selleck ALK inhibitor Primary reasons included feeling healthy, health workers' advice to stop taking medicine when blood pressure normalised, side effects, and using herbs or non-prescription medicines to manage hypertension. Women highlighted difficulties with dietary modifications, and changes in their social relationships. Both men and women spoke about hypertension-related challenges with employment and household economics. These results suggest numerous challenges among adults managing hypertension and HIV in Malawi, and frequent suboptimal adherence to medication. We identified new key themes - the quality of adherence counselling for antihypertensive medication, the effects of hypertension on financial stability, and the role of social relationships in self-care - and encourage further investigation into these topics in low-income, high-burden countries.Women's perceptions of domestic violence vary across societies and cultures and might change by moving to a new society. This study aims to explore newly arrived Afghan women's understandings and perceptions of domestic violence and whether they perceive this as acceptable. Semi-structured interviews were conducted with 21 newly arrived Afghan women in Australia. Interviews were audio-recorded, transcribed, and analyzed inductively to generate and organize themes. The findings showed that informants had a sound knowledge and understanding of domestic violence, and many of them identified various forms of violence. Also, informants strongly rejected that violence against women be considered normal or acceptable.Background The contracted gallbladder may predispose to a higher rate of biliary or vasculobiliary injury (VBI). It is usually associated with unclear anatomy due to chronic inflammation and fibrosis in the hepatoduodenal ligament region. Laparoscopic ultrasound (LUS) can very effectively delineate anatomical conditions during cholecystectomy. Our study aimed to compare the visual and ultrasonographic navigation around the shrunken gallbladder. Materials and Methods The study group consisted of 612 patients qualified for laparoscopic cholecystectomy. The shrunken gallbladder was diagnosed intraoperatively in 13 patients (2.1%). In 6 patients, the only intraoperative navigation method was a visual evaluation of anatomical conditions, and in 7 patients, the method was LUS. Results The operating time and the length of hospital stay after surgery were significantly lower, the number of conversions was insignificantly lower, and the number of successful visualization of anatomical conditions was significantly higher in the LUS group.

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