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Then we discuss several methods for quantifying drug synergism. The advantages and disadvantages with these methods are also provided, and finally, we discuss important next directions in this area.Due to inadequate resources and limited access to healthy foods, residents who live in food deserts struggle to maintain a healthful diet. Living in a food desert increases the risk of developing diet-related chronic diseases such as obesity. Local farmers' markets serve as community-level interventions, bringing healthy food options to food deserts. This study explores the relationship between food deserts, placement of farmers' markets, and availability of food assistance programs in the state of Hawai'i. Data are from the 2017 United States Department of Agriculture (USDA) Food Access Research Atlas and the USDA Farmers' Market Directory. Farmers' market addresses were geocoded in ArcGIS 10.3. Descriptive statistics and spatial visualization were used to explore census tract level relationships. Of the Hawai'i census tracts, 10% are food deserts. Sixteen of the 101 registered farmers markets are located within a food desert. Of these markets, 28.7% accept Farmers' Market Nutrition Program coupons, 0% accept Women, Infants, and Children Fruit and Vegetable Checks, and 39.6% accept Supplemental Nutrition Assistance Program benefits. Fewer than 20% of farmers' markets in Hawai'i are located in food deserts, and few accept food assistance programs. Fresh food is less accessible to low-income residents in these areas and lack of access to fresh food is associated with diet-related chronic diseases. To reduce food insecurity, farmers' markets could accept food assistance program funds. Additional farmers' markets could be established in food deserts to increase availability of healthy food, thereby reducing the population's risk of developing obesity and diet-related chronic diseases. ©Copyright 2020 by University Health Partners of Hawai‘i (UHP Hawai‘i).The tomato is the most important vegetable globally. In England, outdoor tomatoes are widely grown by amateur gardeners, with the number of their allotment plots exceeding 150000. For instance, in Germany, only about 16% of tomato plants are cultivated according to organic standards, although these rates are expected to increase. Breeding for yield and fruit quality can increase resource efficiency. Therefore, we need to evaluate the variability of yield and fruit quality parameters, to calculate the heritability of these traits and to identify superior genotypes for organic outdoor tomato production and breeding. With these aims, we grew 24 tomato genotypes of diverse origins in a two-year field trial. The heritability of quality traits such as glucose, fructose, organic acid, and lycopene was high. The medium heritability for yield suggests that trials with a larger number of locations are needed for the reliable selection of this character. Negative correlations of sugar concentrations with fruit weight and of organic acid concentration with fruit weight and yield suggest trade-offs in breeding for larger fruits and higher yields. Breeding for increased lycopene content is not subject to these challenges; the concentrations of the primary metabolite sugars and organic acids are positively correlated. Copyright © 2020 Christian Zörb et al.Recent advances in the field of two-dimensional (2D) materials have led to new electronic and photonic devices enabled by their unique properties at atomic thickness. Structuring 2D materials into desired patterns on substrates is often an essential and foremost step for the optimum performance of the functional devices. In this regard, optical patterning of 2D materials has received enormous interest due to its advantages of high-throughput, site-specific, and on-demand fabrication. Recent years have witnessed scientific reports of a variety of optical techniques applicable to patterning 2D materials. In this minireview, we present the state-of-the-art optical patterning of 2D materials, including laser thinning, doping, phase transition, oxidation, and ablation. Several applications based on optically patterned 2D materials will be discussed as well. With further developments, optical patterning is expected to hold the key in pushing the frontiers of manufacturing and applications of 2D materials. Copyright © 2020 Pavana Siddhartha Kollipara et al.The effects of V and Ce concentrations (each varying in the 0-100% range) in vanadia-ceria multiphase systems are investigated for synthesis gas production via thermochemical redox cycles of CO2 and H2O splitting coupled to methane partial oxidation reactions. The oxidation of prepared oxygen carriers is performed by separate and sequential CO2 and H2O splitting reactions. Structural and chemical analyses of the mixed-metal oxides revealed important information about the Ce and V interactions affecting their crystal phases and redox characteristics. Pure CeO2 and pure V2O5 are found to offer the lowest and highest oxygen exchange capacities and syngas production performance, respectively. The mixed-oxide systems provide a balanced performance their oxygen exchange capacity is up to 5 times higher than that of pure CeO2 while decreasing the extent of methane cracking. check details The addition of 25% V to CeO2 results in an optimum mixture of CeO2 and CeVO4 for enhanced CO2 and H2O splitting. At higher V concentrations, cyclic carbide formation and oxidation result in a syngas yield higher than that for pure CeO2. Copyright © 2020 Asim Riaz et al.The contact angle, as a vital measured parameter of wettability of material surface, has long been in dispute whether it is affected by gravity. Herein, we measured the advancing and receding contact angles on extremely low contact angle hysteresis surfaces under different gravities (1-8G) and found that both of them decrease with the increase of the gravity. The underlying mechanism is revealed to be the contact angle hysteresis and the deformation of the liquid-vapor interface away from the solid surface caused by gradient distribution of the hydrostatic pressure. The real contact angle is not affected by gravity and cannot measured by an optical method. The measured apparent contact angles are angles of inclination of the liquid-vapor interface away from the solid surface. Furthermore, a new equation is proposed based on the balance of forces acting on the three-phase contact region, which quantitatively reveals the relation of the apparent contact angle with the interfacial tensions and gravity. This finding can provide new horizons for solving the debate on whether gravity affects the contact angle and may be useful for the accurate measurement of the contact angle and the development of a new contact angle measurement system.