Gustafsonreese3676

2, p = 0.006). The same phenomenon was observed in newborns (unweighted-UniFrac full tree, r = 0.174, p = 0.031). Maternal alcohol consumption frequency showed positive associations with maternal Phascolarctobacterium (p = 0.032) and Blautia (p = 0.019); maternal Faecalibacterium (p = 0.013) was negatively correlated with frequency of alcohol consumption. As for newborns, a positive relationship showed between Megamonas (p = 0.035) and newborns with maternal alcohol consumption. The diet was not associated with both maternal and infant's gut microbiota. (4) Conclusions Maternal alcohol consumption during pregnancy influenced the gut microbiota on both mothers and the newborns. Future research is needed to explore these relationships in a lager birth cohort. Understanding the long-term effect of alcohol consumption on maternal and newborns' gut microbiota is needed.The continued expand of the coronavirus disease 19 (COVID-19) pandemic, confinement measures and an urgent change in the education of nursing students from traditional education to distance learning throughout the country affect the mental health of university students. This study analyzed state-trait anxiety levels of nursing students because of e-Learning during two periods of the COVID-19 confinement. A mixed follow-up study was used, which evaluates the same cohort cross-sectionally but with a longitudinal component. A sample of 460 nursing students of the Nursing Degree at the University of Lorca (Murcia) and University of Almería (Spain) completed an online anxiety level questionnaire using the Spielberger State-Trait Anxiety Inventory (STAI) during the first and fourth weeks of the COVID-19 confinement. Total anxiety levels increased in the fourth week, as compared to the first week (first week 50.4 ± 20.8 and fourth week 59.9 ± 10.6 (p less then 0.001)). The linear regression model showed that the significant predictors for STAI anxiety in nursing students were being in the last year of the degree program, being female, and spending confinement in a house without a garden. In general, most nursing students were emotionally affected by high levels of anxiety of state-trait during the COVID-19 outbreak.VANETs (Vehicular Ad hoc Networks) operating in conjunction with road-side infrastructure connecting road-side infrastructure are an emerging field of wireless communication technology in the vehicular communication's domain. For VANETs, the IEEE 802.11p-based ITS-G5 is one of the key standards for communication globally. This research work integrates the ITS-G5 with a cellular-based 5G Test Network (5GTN). Dulaglutide datasheet The resulting advanced heterogeneous Vehicular Network (VN) test-bed works as an effective platform for traffic safety between vehicles and road-side-infrastructure. This test-bed network provides a flexible framework to exploit vehicle-based weather data and road observation information, creating a service architecture for VANETs that supports real-time intelligent traffic services. The network studied in this paper aims to deliver improved road safety by providing real-time weather forecast, road friction information and road traffic related services. This article presents the implementation of a realistic test-bed in Northern Finland and the field measurement results of the heterogeneous VANETs considering the speed of vehicle, latency, good-put time and throughput. The field measurement results have been obtained in a state-of-the-art hybrid VANET system supporting special road weather services. link2 Based on field measurement results, we suggest an efficient solution for a comprehensive hybrid vehicular networking infrastructure exploiting road weather information.The aerostatic spindle in the ultra-precision machine tool shows the complex multi-field coupling dynamics behavior under working condition. The numerical investigation helps to better understand the dynamic characteristics of the aerostatic spindle and improve its structure and performance with low cost. A multi-field coupling 5-DOF dynamics model for the aerostatic spindle is proposed in this paper, which considers the interaction between the air film, spindle shaft and the motor. The restoring force method is employed to deal with the times varying air film force, the transient Reynolds equation of the aerostatic journal bearing and the aerostatic thrust bearing is solved using ADI method and Thomas method. The transient air film pressure of aerostatic bearings is obtained which clearly presents the influence induced by the tilt motion of the spindle shaft. The motion trajectory of the spindle shaft is obtained which shows different stability of the shaft under different external forces. The dynamics model shows good performance on simulating the multi-field coupling behavior of the aerostatic spindle under external force. which is quite meaningful and useful for the further research on the dynamic characteristics of the aerostatic spindle.This work considers a base station equipped with an M-antenna uniform linear array and L users under line-of-sight conditions. As a result, one can derive an exact series expansion necessary to calculate the mean sum-rate channel capacity. This scenario leads to a mathematical problem where the joint probability density function (JPDF) of the eigenvalues of a Vandermonde matrix WWH are necessary, where W is the channel matrix. However, differently from the channel Rayleigh distributed, this joint PDF is not known in the literature. To circumvent this problem, we employ Taylor's series expansion and present a result where the moments of mn are computed. To calculate this quantity, we resort to the integer partition theory and present an exact expression for mn. Furthermore, we also find an upper bound for the mean sum-rate capacity through Jensen's inequality. All the results were validated by Monte Carlo numerical simulation.Short 6 mm dental implants are considered as an alternative to the maxillary sinus elevation and bone augmentation procedure where there is a reduced alveolar ridge height. The aim of this study was to compare the implant survival rate between short dental implants (6 mm) and regular length implants (11-13 mm) when placed in combination with bone grafting and loaded with a single non splinted crown, seven years after placing the implant. It was conducted as a controlled clinical study of 30 patients with partial edentulism in the posterior maxilla. The protocol included radiological and clinical evaluation of the C/I ratio (length of the superstructure divided by the length of the implant crestal part), marginal bone level (MBL), ultrasonography measurement of soft tissue surrounding implant (STT), patient-reported outcomes, and biological and technical complications. A total number of 28 implants (93%) remained integrated during follow-up period. MBL of 0.50 and 0.52 mm was observed for short implants and regular implants, respectively. MBL was checked for correlation with STT, and a negative correlation was found between MBL STT. Our study has demonstrated a significantly lower implant survival rate for short implants compared to regular implants (87% compared to 100%). Despite the loss of several implants, good clinical results were achieved in the remaining implants in both groups. It is, therefore, worth considering short implants as an alternative to regular implants with a sinus lift surgery.Excessive daytime sleepiness is increasingly being recognized as a major global health concern. However, there have been few studies related to sleepiness and its associated factors in elementary school children. In Japan, all schools were closed from February to May 2020 to prevent coronavirus disease 2019 (COVID-19) outbreaks. The aim of this study was to identify changes in the subjective sleepiness of pupils during the 1.5-year period and to elucidate factors associated with changes in sleepiness. Questionnaire surveys about pupils' sleep habits and the Japanese version of the Pediatric Daytime Sleepiness Scale (PDSS-J) were conducted longitudinally at one elementary school in June 2019, January 2020, and June 2020. The average ∆PDSS score was 0.94 ± 5.51 (mean ± standard deviation) from June 2019 to January 2020 and -1.65 ± 5.71 (t[498] = 6.13, p less then 0.01) from January 2020 to June 2020. Univariate and multivariate logistic regression analyses revealed that decreasing social jetlag was associated with decreasing PDSS scores (OR = 0.77, 95% CI 0.62-0.96, p = 0.02) during the school closure. A less restrictive school schedule secondary to a COVID-19-related school closure decreased sleepiness in children and was associated with decreasing social jetlag.BST204 is a purified ginseng dry extract that has an inhibitory effect on lipopolysaccharide-induced inflammatory responses, but its effect on muscle atrophy is yet to be investigated. In this study, C2C12 myoblasts were induced to differentiate for three days followed by the treatment of dexamethasone (DEX), a corticosteroid drug, with vehicle or BST204 for one day and subjected to immunoblotting, immunocytochemistry, qRT-PCR and biochemical analysis for mitochondrial function. BST204 alleviates the myotube atrophic effect mediated by DEX via the activation of protein kinase B/mammalian target of rapamycin (Akt/mTOR) signaling. Through this pathway, BST204 suppresses the expression of muscle-specific E3 ubiquitin ligases contributing to the enhanced myotube formation and enlarged myotube diameter in DEX-treated myotubes. In addition, BST204 treatment significantly decreases the mitochondrial reactive oxygen species production in DEX-treated myotubes. Furthermore, BST204 improves mitochondrial function by upregulating the expression of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC1α) in DEX-induced myotube atrophy. This study provides a mechanistic insight into the effect of BST204 on DEX-induced myotube atrophy, suggesting that BST204 has protective effects against the toxicity of a corticosteroid drug in muscle and promising potential as a nutraceutical remedy for the treatment of muscle weakness and atrophy.High-sensitivity and simple, low-cost readout are desirable features for sensors independent of the application area. Micro-cantilever sensors use the deflection induced by the analyte presence to achieve high-sensitivity but possess complex electronic readouts. Current holographic sensors probe the analyte presence by measuring changes in their optical properties, have a simpler low-cost readout, but their sensitivity can be further improved. Here, the two working principles were combined to obtain a new hybrid sensor with enhanced sensitivity. The diffractive element, a holographically patterned thin photopolymer layer, was placed on a polymer (polydimethylsiloxane) layer forming a bi-layer macro-cantilever. The different responses of the layers to analyte presence lead to cantilever deflection. link3 The sensitivity and detection limits were evaluated by measuring the variation in cantilever deflection and diffraction efficiency with relative humidity. It was observed that the sensitivity is tunable by controlling the spatial frequency of the photopolymer gratings and the cantilever thickness. The sensor deflection was also visible to the naked eye, making it a simple, user-friendly device. The hybrid sensor diffraction efficiency response to the target analyte had an increased sensitivity (10-fold when compared with the cantilever or holographic modes operating independently), requiring a minimum upturn in the readout complexity.