Gormsenhagen2676

The activPAL linear cadence-metabolic equivalents (METs) equation poorly estimates activity intensity. The magnitude of acceleration in three directional planes may be a superior predictor of activity intensity than stepping cadence, with accelerometry count thresholds developed in children/adolescent populations. We extracted the proprietary accelerometer-derived information to develop a counts-METs model and cross-validates it in laboratory and free-living conditions. Forty adults (25±6 years) wore an activPAL during a 7-stage progressive treadmill protocol (criterion indirect calorimetry). Tri-axial accelerometry-derived activity counts (vector magnitude) and METs data from a subset of participants (n = 20) were modelled (R2=0.76) and the regression equation evaluated in the remaining participants (n = 20). Thirty-two of these participants wore the activPAL during free-living conditions (n = 192-d; criterion PiezoRxD monitor). The absolute percent error of the counts-METs model in the laboratory cross-validation was 18±13%, with equivalence testing determinining equivalent MET values to indirect calorimetry during the slowest (1.5 mph) and fastest (4.0-4.5 mph) stages. In free-living conditions, the model accurately quantified light- and moderate-intensity physical activity but underestimated vigorous-intensity activity (6.5±11.3 vs. 5.5±20.8 mins/day; p less then 0.001). We developed and present a data analysis method using the activPAL tri-axial accelerometry counts to improve estimations of physical activity intensity in controlled laboratory settings and uncontrolled free-living settings.

Would there be differences in muscle activation between healthy subjects' (HS) dominant leg and transfemoral amputees' (TFA) intact-leg/contralateral-limb (IL) during normal transient-state walking speed?

The muscle activation patterns are obtained by calculating the linear envelope of the EMG signals for each group. The activation patterns/temporal changes are compared between-population using statistical parametric mapping (SPM).

Individual muscle activity showed significant differences in all muscles except vastus lateralis (VL), semitendinosus (SEM) and tensor fascia latae (TFL) activities.

The information could be used by the therapists to prevent secondary physical conditions and prosthetic companies to improve the mobility of the amputees.

The information could be used by the therapists to prevent secondary physical conditions and prosthetic companies to improve the mobility of the amputees.In this study, we investigated a method allowing the determination of the femur bone surface as well as its mechanical axis from some easy-to-identify bony landmarks. The reconstruction of the whole femur is therefore performed from these landmarks using a Statistical Shape Model (SSM). The aim of this research is therefore to assess the impact of the number, the position, and the accuracy of the landmarks for the reconstruction of the femur and the determination of its related mechanical axis, an important clinical parameter to consider for the lower limb analysis. Two statistical femur models were created from our in-house dataset and a publicly available dataset. Both were evaluated in terms of average point-to-point surface distance error and through the mechanical axis of the femur. Furthermore, the clinical impact of using landmarks on the skin in replacement of bony landmarks is investigated. The predicted proximal femurs from bony landmarks were more accurate compared to on-skin landmarks while both had less than 3.5∘ degrees mechanical axis angle deviation error. The results regarding the non-invasive determination of the mechanical axis are very encouraging and could open very interesting clinical perspectives for the analysis of the lower limb either for orthopedics or functional rehabilitation.

Gross taper failure (GTF) is a rare but catastrophic failure mode of the head-stem-taper junction of hip prostheses, facilitated by massive material loss. GTF is a two stage process initiated by corrosion leading to head bottoming out, followed by abrasive wear due to the head rotating on the stem. The purpose of this study was to reproduce the clinical failure patterns and to determine the material loss during simulated gait.

Six cobalt-chromium alloy heads (36mm, 12/14 taper) with three different head lengths (short / medium / extra long) were combined with stem taper replicas made from titanium alloy sized to achieve bottoming out. A hip simulator was used to simulate gait loading after (ISO 14242-1 for 2 million cycles).

Wear patterns from in-vitro testing match the clinical failure patterns. Stem taper wear increased linearly with time (p<0.001). After two million cycles the material loss of short / medium / extra long heads was (M+-STD) 1168±242mg / 400±23mg / 94±12mg on the stem side and 46±36mg / 46±24mg / 70±8mg on the head side. Stem taper wear decreased with increasing head length (p=0.01), whereas clinical failures are mostly seen for long and extra long heads.

Wear patterns from in-vitro testing match the clinical failure patterns. Stem taper wear increased linearly with time (p less then 0.001). After two million cycles the material loss of short / medium / extra long heads was (M+-STD) 1168±242 mg / 400±23 mg / 94±12 mg on the stem side and 46±36 mg / 46±24 mg / 70±8 mg on the head side. Stem taper wear decreased with increasing head length (p=0.01), whereas clinical failures are mostly seen for long and extra long heads.A non-invasive, no radiation, out-of-hospital automated system is proposed to identify low arch integrated in the design and manufacturing of personalized orthoses using parametric modelling. The aim of the design process is to integrate assistive technology with assessment and prevent low arch progressing to a more serious case - flatfoot. In the automated procedure, we developed an assessment method including reliable thresholds of foot type classification and test protocol to reduce interferences due to preceding activities, an automation to translate scanned data into parametric design for orthotic customization, finite element model evaluating effectiveness of the personalized design, and a personalized comparative test to evaluate the long-term improvement of foot arch shape. Our low arch threshold established by subject-specific 3D models reduced the misclassification rate from 55%, as previously reported to 6.9%. Individuals who engaged in sedentary activity (i.e. sitting) had the greater change in arbecomes symptomatic. selleck chemical Furthermore, non-symptom flatfoot can be detected at early stages and referred to medics for further diagnosis or treatment.Osteotomies during rhinoplasty are usually based on the surgeon's proprioception to determine the number and the strength of the impacts. The aim of this study is to determine whether a hammer instrumented with a force sensor can be used to classify fractures and to determine the location of the osteotome tip. Two lateral osteotomies were realized in nine anatomical subjects using an instrumented hammer recording the evolution of the impact force. Two indicators τ and λ were derived from the signal, and video analysis was used to determine whether the osteotome tip was located in nasal or frontal bone as well as the condition of the bone tissue around the osteotome tip. A machine-learning algorithm was used to predict the condition of bone tissue after each impact. The algorithm was able to predict the condition of the bone after the impacts with an accuracy of 83%, 91%, and 93% when considering a tolerance of 0, 1, and 2 impacts, respectively. Moreover, in nasal bone, the values of τ and λ were significantly lower (p less then 10-10) and higher (p less then 10-4) than in frontal bone, respectively. This study paves the way for the development of the instrumented hammer as a decision support system.This research aims to study the effect of a composite coating comprised of polydopamine (PDA), polytetrafluoroethylene (PTFE), and activated Carbon on the insertion mechanics of surgical needles in tissues i.e., polyvinyl chloride (PVC) tissue phantom and bovine kidney. A needle insertion and extraction test system was designed and constructed to measure the insertion and extraction forces. It was found that the composite coating on the needle surface decreases the maximum average insertion and extraction forces by 62% and 64%, respectively, when tested in PVC tissue phantom and by 49% and 30%, respectively, in bovine kidney tissue. link2 Additionally, an Atomic Force Microscope study was performed to characterize the surface properties of the coated needles. link3 It was found that the composite coating reduced the friction force on the needle surface by 65.7%. The decrease in these forces is critical in minimizing tissue damage and decreasing needle path deviation or deflection during percutaneous procedures.While it is possible to determine the irradiance and spectral content for a given neonatal phototherapy device at various locations over a neonate's surface, this does not allow estimation of the total rate of energy delivery within a specific spectral range over the neonate's exposed body surface. A series of 192 blue wavelength enhanced silicon photodiodes was distributed over the surface of a commercially available newborn body shape and connected to a specially designed interface circuit. Placement of photosensors over the surface of the baby shape was determined with consideration of the surface area of twelve specific anatomical areas where each was allocated 16 individual photodiodes. Calibration of detection channels for specific wavelength intervals was undertaken using a Bentham dmc150 spectroradiometer system and also a separate hand held spectroradiometer. This made it possible to estimate the effective integrated dose rate in Watts for specific wavelength intervals such as 460 nm to 490 nm as identified by the American Academy of Pediatrics for phototherapy lamp devices. This allowed identification of dose rate contributions from specific anatomical areas. Initial observations are reported for a range of phototherapy lamp systems and the findings are discussed in terms of their predicted relative clinical effectiveness. Options are also discussed in relation to the future development of the reported measurement system.Pediatric patients may require magnesium replacement to treat life-threatening emergencies such as torsades de pointe or asthma exacerbations, as well as for the general replacement of magnesium in patients with hypomagnesemia. Clinicians must be aware of recommendations for magnesium administration as the route, dose, timing of administration, and formulation of magnesium can differ for each indication. It is imperative for clinicians to ensure that magnesium is appropriately administered to effectively treat the presenting indication and avoid adverse effects.

The present study aimed to assess differences in postoperative morbidity between prophylactic and symptomatic third molar removals, and to assess the effect of age on the recovery of the patient.

Patients admitted for third molar removal were prospectively followed up four times during treatment in context of the M3BE study. Data were collected through pre-, peri and postoperative surveys (days 3 and 10). Uni- and multivariable logistic regression was used to assess the probability of postoperative symptoms of discomfort on day 3 and day 10 according to several patient- and surgery-related predictive factors (age, gender, indication for removal, method of extraction, anesthesia and number of extracted maxillary and/or mandibular third molars).

In total, 6010 patients with a mean age of 25.2 (± 11.2) underwent 6347 surgeries to have 15,357 third molars removed. Frequently observed symptoms of postoperative discomfort were pain, trismus and swelling, all of which were transient in nature with steep decreases from postoperative days 3 to 10.