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The liver is uniquely bestowed with an ability to regenerate following a surgical or toxicant insult. One of the most researched models to demonstrate the regenerative potential of this organ is the partial hepatectomy model where two-thirds of the liver is surgically resected. The remnant liver replenishes the lost mass within 10-14 days in mice. The distinctive ability of the liver to regenerate has allowed living donor and split liver transplantation. One signaling pathway shown to be activated during the process of regeneration to contribute towards the mass and functional recovery of the liver is Wnt/β-catenin pathway. Very early after any insult to the liver, the cell-molecule circuitry of Wnt/β-catenin pathway is set into motion with the release of specific Wnt ligands from sinusoidal endothelial cells and macrophages, which in a paracrine manner, engage Frizzled and LDL-Related Protein-5/6 co-receptors on hepatocytes to stabilize β-catenin inducing its nuclear translocation. Nuclear β-catenin interacts with T-cell factor family of transcription factors to induce target genes including Cyclin D1 for proliferation, and others, for regulating hepatocyte function. Working in collaboration with other signaling pathways, Wnt/β-catenin signaling contributes to the restoration process without any compromise of function at any stage. Also, stimulation of this pathway through innovative means, induces liver regeneration when this process is exhausted or compromised, and thus has applications in the treatment of End Stage Liver Disease and in the field of liver transplantation. Thus, Wnt/β-catenin signaling pathway is highly relevant in the discipline of hepatic regenerative medicine.

The aim of this study was to investigate the changes in Chinese residents' psychological state and its influencing factors after the Wuhan shutdown on January 23, 2020.

Two surveys were conducted on February 1-5 and February 20-24, separately, using an online self-administrated questionnaire among 3145 and 3814 participants, respectively. Subjective indicators of daily-life changes include level of attention, risk of infection, impact of daily life, self-perceived health status, and mental health help-seeking. Individual scores on changes in anxiety, depression, and stress were generated by 6-item, 4-item, and 3-item questions. A multivariate regression model was fitted in each survey, separately and combined.

A total of 6959 residents participated in the study, with 32.78% male and 67.22% female, people living in Wuhan and other cities in Hubei Province accounted for 25.22% and 18.85%, respectively. One week after the Wuhan shutdown, their anxiety, depression, and stress had all increased. Compared with the first survey, the changes in the scores of anxiety, depression, and stress in the second survey were decreased (β = -1.220, -0.798, and -0.623, all P < 0.001). The level of attention, risk of infection, and self-perceived health status tended to be positively associated with the changes in the scores of anxiety, depression, and stress.

The study showed that the lives and psychological conditions of residents had undergone negative changes after the Wuhan shutdown, but the measures taken during this period were effective. These results may provide guidance for public health policies in other countries and regions.

The study showed that the lives and psychological conditions of residents had undergone negative changes after the Wuhan shutdown, but the measures taken during this period were effective. These results may provide guidance for public health policies in other countries and regions.

Maternal nutrition during pregnancy is a key factor influencing birth outcome. Dietary diversity is a proxy for multiple macro- and/or micronutrient sufficiency of an individual's diet. This systematic review aimed to summarize the findings on the association between maternal dietary diversity during pregnancy and the risk of low birth weight (LBW) in newborns.

This is a systematic review study.

Google and the PubMed, Scopus and Google Scholar databases were searched to extract original studies on humans published until June 2020, without date restrictions. There was no limitation regarding geographic region or economic condition of countries. Duplicated and irrelevant studies were screened out and data were obtained through critical analysis.

Articles that examined the association between maternal dietary diversity during pregnancy and the risk of LBW in infants were included.

Of the 98 studies retrieved, 15 articles were included in the final review. All included articles represent low- and middle-income countries. 1-Methylnicotinamide modulator 80% of the studies (n=12) indicated that low maternal dietary diversity during pregnancy is associated with an increased risk of LBW infants. Three studies that included a small number of LBW infants and did not take into account factors which may bias study results, failed to show this association.

The results suggest that low maternal dietary diversity during pregnancy may be associated with the risk of LBW, more specifically in developing countries. Dietary diversity might be a valuable predictor of maternal nutrition during pregnancy and the chance of giving birth to a LBW infant.

The results suggest that low maternal dietary diversity during pregnancy may be associated with the risk of LBW, more specifically in developing countries. Dietary diversity might be a valuable predictor of maternal nutrition during pregnancy and the chance of giving birth to a LBW infant.

There are numerous health effects associated with excess sugar-sweetened beverage (SSB) consumption. Interventions aimed at reducing population-level consumption require understanding of the relevant barriers and facilitators. This study aimed to identify the variables with the strongest relationship with intentions to reduce SSB consumption from a suite of variables derived from the literature.

Random digit dialling of landline and mobile phones was used to survey adults using Computer Assisted Telephone Interviews. The outcome variable was 'likelihood of reducing SSB consumption in next 6 months' and predictor variables were demographics, SSB attitudes and behaviour, health risk perceptions and social/environmental exposure.

Australia.

A subsample of 1630 regular SSB consumers from a nationally representative sample of 3430 Australian adults (38% female, 51% aged 18-45 years, 56% overweight or obese).

Respondents indicated that they were 'not at all' (30.1%), 'somewhat' (43.9%) and 'very' likely (25.