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Sixty knees were revised, with progression of disease in another compartment the commonest reason. Eighty eight percent were revised using a primary prosthesis. For patients over the age of 65years at the time of index procedure, 93% died with a functioning prosthesis in situ.

Medial UKA demonstrates good long-term function and survivorship, and represents an excellent surgical option for patients aged over 65years of age, where few patients will require a revision procedure.

IV.

IV.The diagnosis of premature ventricular contractions (PVC) is presumptively based on the presence of frequent symptoms. Particularly in patients with a relatively low PVC burden, the relationship between the PVCs and an individual arrhythmia substrate can be challenging to ascertain. AZD1080 chemical structure Late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (CMR) has been found to be beneficial in identifying the presence of potential individual arrhythmia substrates even in patients with normal left ventricular function. Consequently, CMR has been useful in risk stratification of patients with PVCs. The authors aimed to demonstrate and discuss the current role and future use of CMR in the diagnostic algorithm to guide PVC ablation.

To estimate the long-term effect of low-dose radiotherapy of painful plantar calcaneal spurs, and to verify possible prognostic factors.

In this retrospective unicenter study, electronic patient files of patients with painful plantar calcaneal spurs treated with low-dose radiotherapy between July 2009 and February 2020 were reviewed. The low-dose radiotherapy consisted of atotal dose of 3.0 Gy given with afraction dose of 0.5 Gy three times aweek. The pain reduction was estimated using apatient questionnaire with avisual analogue scale. Kaplan-Meier statistics and Cox regression analysis were used for the statistical analysis.

Altogether, 864 heels of 666patients were reviewed. The probability of an insufficient pain control 10years after low-dose radiotherapy was 45.9% (95% confidence interval 39.4-52.4%) in the subset of patients with aminimum follow-up of 3months (582 heels of 467patients). Patients with an unsatisfactory pain reduction 3months after low-dose radiotherapy were offered are-irradiationntar calcaneal spurs. An initial aggravation of pain during or within 3 months after radiotherapy was identified as unfavorable prognostic factor for the treatment outcome. Re-irradiation of patients with an unsatisfactory pain reduction after low-dose radiotherapy is effective and should be offered to patients.

To retrospectively evaluate the biochemical no evidence of disease (bNED) and late side effects after adjuvant radiotherapy in prostate cancer patients.

Patients (n = 85) treated with external beam radiotherapy between 1997 and 2013 following radical prostatectomy (RPE) with pathological tumour stage pT2c with positive surgical margins or pT3 and pT4 tumours with or without positive margins who presented with apostoperative and apreradiation prostate-specific antigen (PSA) level below 0.1 ng/ml. The mean dose applied was 66 Gy with conventional fractionation (4field box-technique). No androgen deprivation therapy was administered, and patients with incomplete data (missing Gleason score, pT stage, or PSA values postoperatively and/or prior to radiation at the presentation at our department) have been excluded from the analysis. Biochemical recurrence was defined as reaching aPSA level > 0.2 ng/ml during follow-up and bNED rates were assessed. In addition, patients were divided into two groups accordingur control rates.

 15%) according to the Roach formula show significant worse tumour control rates.

Since the outbreak of coronavirus disease 2019 (COVID-19) pandemic, healthcare systems have focused their efforts into finding atreatment to avoid the fatal outcomes of severe acute respiratory syndrome due to coronavirus‑2 (SARS-CoV-2). Benefits and risks of systemic treatments remain unclear, with multiple clinical trials still ongoing. Radiotherapy could play arole in reducing the inflammatory response in the lungs and relieve life-threatening symptoms.

We designed aprospective study of Ultra-Low Doses of Therapy with Radiation Applied to COVID-19 (ULTRA-COVID) for patients who suffer pneumonia, are not candidates for invasive mechanical ventilation and show no improvement with medical therapy.

We present the preliminary results of two patients diagnosed with COVID-19 pneumonia treated with ULTRA-COVID. After one radiotherapy session, significant clinical response and agood radiological response was observed in both cases, resulting in both patients being discharged from hospital in less than 2weeks after radiation treatment.

Preliminary clinical and radiological results suggest apotential benefit of treating COVID-19 pneumonia with ULTRA-COVID. ClinicalTrials.gov Identifier NCT04394182.

Preliminary clinical and radiological results suggest a potential benefit of treating COVID-19 pneumonia with ULTRA-COVID. ClinicalTrials.gov Identifier NCT04394182.

Geriatric trauma patients present physiological challenges to care providers. A nationwide analysis was performed to evaluate the roles of age alone versus age-associated comorbidities in the morbidity and mortality of elderly patients with blunt abdominal trauma (BAT).

Patients with BAT registered in the National Trauma Data Bank from 2013 to 2015 were analyzed using propensity score matching (PSM) to evaluate the mortality rate, complication rate, hospital length of stay (LOS), intensive care unit (ICU) LOS and ventilator days between young (age < 65) and elderly (age ≥ 65) patients. An adjusted multivariate logistic regression (MLR) model was also used to evaluate the effect of age itself and age-associated comorbidities on mortality.

There were 41,880 patients with BAT during the study period. In elderly patients, the injury severity score (ISS) decreased with age, but the mortality rate increased inversely (from 5.0 to 13.5%). Under a similar condition and proportion of age-associated comorbidities after a well-batched PSM analysis, elderly patients had significantly higher mortality rates (8.0% vs. 1.9%, p < 0.001), higher complication rates (35.1% vs. 30.6%, p < 0.001), longer hospital LOS (8.9 vs. 8.1days, p < 0.001), longer ICU LOS (3.7 vs. 2.7days, p < 0.001) and more ventilator days (1.1 vs. 0.5days, p < 0.001) than young patients. Furthermore, the MLR analysis showed that age itself served as an independent factor for mortality (odds ratio 1.049, 95% CI 1.043-1.055, p < 0.001), but age-associated comorbidity was not.

In patients with BAT, age itself appeared to have an independent and deleterious effect on mortality, but age-associated comorbidity did not.

In patients with BAT, age itself appeared to have an independent and deleterious effect on mortality, but age-associated comorbidity did not.

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