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Reducing opioid prescriptions after third molar extraction may decrease the risk of opioid dependence. This study compared prescribed morphine milligram equivalents (MMEs) in patients undergoing mandibular third molar removal with and without use of liposomal bupivacaine (LB).

This retrospective cross-sectional study included deidentified data from electronic medical records of patients who underwent extraction of ≥1 partial bony-or full bony-impacted mandibular third molar at 2 oral surgery centers in the United States in 2012 or 2018. The primary predictor variable was use of LB 133mg. The primary outcome variable was total prescribed opioids in MMEs. The secondary outcome variable was rate of prescription refills. Both univariate and multivariable regression analyses were used to compare MMEs between groups with a significance level of P<.05.

The study sample included 600 subjects (n=300 each for LB and non-LB groups). Mean age (22-24years) and sex distribution (55%-58% female) were comparable bets undergoing third molar extraction and receiving LB were prescribed significantly fewer opioids than patients who did not receive LB, with a lower refill rate. Use of LB may reduce opioid prescriptions for postsurgical analgesia.

The purpose of this study was to evaluate the effectiveness of zygomatic complex fracture reduction by percutaneous bone hook traction as a minimally invasive treatment.

A retrospective case series analysis of 24 patients who underwent unilateral isolated zygomatic complex fracture reduction by percutaneous bone hook traction between June 2014 and June 2019 was performed. Patients who complained of other accompanying maxillofacial fractures or ocular problems were excluded. Postoperative radiographs were used to assess the esthetic appearance and treatment response, including complications, in all patients.

Operation was performed within a mean time of 5.3days after injury. Honokiol Closed reduction by percutaneous bone hook traction was performed in 24 patients. At a regular follow-up period of 6months, postoperative radiographs showed symmetrical outcomes of facial contours and bony union without zygomatic collapse. All patients were satisfied with the symmetrical contours of the zygomatic complex and experienced no complications. Three of the 7 patients had paresthesia in the infraorbital region after injury and regressed postoperatively.

Percutaneous bone hook traction could be an alternative treatment method for simple noncommunicated zygomatic complex fractures without preoperative ocular problems 7days after injury. Deep understanding of the operative indication, choosing a suitable operation time, and experienced surgeons are keys to effectively using this economical, reliable, and effective approach.

Percutaneous bone hook traction could be an alternative treatment method for simple noncommunicated zygomatic complex fractures without preoperative ocular problems 7 days after injury. Deep understanding of the operative indication, choosing a suitable operation time, and experienced surgeons are keys to effectively using this economical, reliable, and effective approach.

Several researchers have proposed and investigated the prognostic implications of various parameters, but have failed to provide concrete evidence regarding the inclusion or exclusion of histopathological features while clinically managing an oral squamous cell carcinoma (OSCC) case. The study purpose was to measure the prognostic values of a set of key histologic features and its association with its clinical outcome-5-year survival.

This is a prospective cohort study and the sample was composed of patients treated for OSCC (April 2014 - March 2015). The predictor variables included pattern of tumor invasion (POI), stromal inflammation, angiogenesis, and vascular invasion with the outcome being survival of subjects observed over this 5-year period. Sociodemographic data (age, sex, marital status, systemic disease, habits etc), clinical staging and TNM staging were also recorded. We used multivariate regression analysis for predictor analysis; Kaplan-Meier survival curves and Cox hazard modeling was also n about the overall survival and prognosis.

To characterise current management of chemotherapy-induced nausea and vomiting in Spain, as well as professional adherence to antiemetic guidelines.

Retrospective observational study. A multicenter has been designed including 360 patient case files from 18 hospitals. The involvement of pharmacists and nurses was studied, and also indicators of structure, process, and selected outcomes previously recruited from antiemetic guidelines.

We found 94.4% of hospitals used a written protocol for managing chemotherapy-induced nausea and vomiting and only 44.4% had educational programs for patients regarding this. Patients were prescribed antiemetic prophylactic treatment for delayed emesis in varying degree between highly and moderately emetogenic chemotherapy (77.8% and 58.9%, respectively). Dexamethasone was the most prescribed antiemetic drug for patients receiving highly and moderately emetogenic chemotherapy (98.3% and 90%, respectively), followed by ondansetron (68.9% and 95%, respectively). Nursing was more involved than pharmacy units in evaluating emetic risk factors in patients (64.7% vs 21.4%), and tracking symptom onset (88.2% vs 57.1%) and adherence to treatment (94.1% vs 28.6%). Pharmacy units were more involved than nursing in choosing the antiemetic treatment (78.6% vs 47%).

Although antiemetic guidelines were used by all hospitals, there were differences in management of chemotherapy-induced nausea and vomiting. Increased education directed towards patients and oncology professionals is needed to improve adherence.

Although antiemetic guidelines were used by all hospitals, there were differences in management of chemotherapy-induced nausea and vomiting. Increased education directed towards patients and oncology professionals is needed to improve adherence.

To describe the entry of cataract surgery into the British Isles.

Handbills, books, and other historical sources were reviewed to determine when cataract surgery was first performed in the region.

Roman artifacts suggest that couching was performed in the British Isles in antiquity. Seemingly miraculous cures of blindness during the early Middle Ages might be consistent with couching. However, there is no strong evidence of medieval cataract surgery in the region. Cataract couching probably arrived in England by the 1560s, in Scotland by 1595, in Ireland by 1684, and in Anglo-America by 1751. Before the 18

century, cataract surgery was taught within families, apprenticeships, and mountebank troupes. Beginning in the 17

century, congenital cataract surgery permitted surgeons to tout their skills, and to explore visual perception. However, in some cases, such as the couching of the 13-year-old Daniel Dolins by surgeon William Cheselden in 1727, whether the cataracts were truly congenital, and whether vision improved in any way, remain in doubt.

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