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We describe differences between urinary tract infection treatment and events reported by nursing homes enrolled in the National Healthcare Safety Network. In 2017, almost 4 times as many antibiotic starts as infection events were reported, suggesting that opportunities exist for antibiotic stewardship and improvement of urinary tract infection reporting.
To establish a series of recommendations based on availableevidence for monitoring surface contamination in the areas devoted tocompounding hazardous drugs in pharmacy departments.
Based on a literature search in the Medline and Embase databases(search period January 2009 to July 2019), as well as on a reviewof standards and recommendations issued by different healthcare organizations, a committee of experts from the Spanish Society of Hospital Pharmacists defined a series of safe practices for handling hazardous drugs and monitoring compounding work surfaces. Recommendation decisions were adopted by consensus among the members of the expert group, considering the recommendations reviewed, the monitoring situation in Spanish hospital departments, and the associated costs.
Ten recommendations were formulated, structured into eight sections.They include aspects related to the drugs to be monitored; the areasto be monitored; when samples should be taken; risk determination andpreparation of a sampling protocol; analytical techniques; contaminationthresholds; and design of an action plan based on the sampling anddecontamination results obtained.
Surface monitoring allows hazardous drugs detection andevaluation of the effectiveness of current protocols for the safe handlingof such drugs in hospital pharmacy departments. The evaluation shouldinclude an analysis of the efficacy of engineering controls, work practicesand cleaning and decontamination processes.
Surface monitoring allows hazardous drugs detection and evaluation of the effectiveness of current protocols for the safe handling of such drugs in hospital pharmacy departments. The evaluation should include an analysis of the efficacy of engineering controls, work practices and cleaning and decontamination processes.All over the world pharmacists are standing up to the challenge of COVID- 19 and showing their commitment to the communities they serve. As the COVID-19 pandemic has tested global health systems to their limits, pharmacy professionals have shown themselves to be an integral part of them. Community pharmacists have supported government initiatives to control the pandemic and have ensured patients continued to receive their medicines. Hospital pharmacists have been moving beyond their specialties to help provide critical care to patients while dealing with ICU drug shortages. Pharmaceutical scientists have been involved in finding effective vaccines and identifying effective treatments. In short, the pharmacy profession has been demonstrating expertise, strength, courage and dedication to care at the highest level. The International Pharmaceutical Federation (FIP), which represents the pharmacy profession globally, has a mission to advance pharmacy worldwide by sharing best pharmacy practice and innovation withtific base. All these advances are supported by scientific studies about our specialty. Finally, FIP expresses its worries about equity of access to medicines during the pandemic, as younger, healthier people in rich countries are vaccinated before people at greater risk in poor countries. It insists it will continue to advocate on this topic as a core component of its global vision. In this article, we share with readers a snapshot of how our profession around the world has adapted to the challenges posed by the COVID-19 pandemic, and our thoughts on the how it is affecting the evolution of pharmacy practice.
The Start Smart-Then Focus tool of the United Kingdom'sNational Health System is a tool to be implemented in antimicrobialstewardship programs. The objective of this work is the adaptation of StartSmart-Then Focus tool to the Spanish health system.
Delphi methodology was used. Two rounds were conductedby email. In the first, a questionnaire was sent out that included the criteriaof the tool. These criteria were independently assessed by 16 experts.They rated the suitability and applicability of each criterion on a scalefrom 1 to 9 and made free comments on each one. The tool was modifiedand sent out again to all the experts. selleck chemical They re-scored the questionnaire individually,while aware of the anonymized results of the first round.
The first questionnaire was made up of 19 indicators. Of these,16 indicators had a median of more than 7 in suitability and applicability.However, regarding applicability, 3 indicators had a median of less than7 and 10 had a minimum of less than 5. From the initial 19 indicators, weobtained 8 final indicators and 8 options were added to the sixth indicator.
It would be very useful to implement the Spanish adaptationof the Start Smart-Then Focus tool in antimicrobial stewardship programs at anational level. It would also contribute to improving the use of antimicrobials.
It would be very useful to implement the Spanish adaptation of the Start Smart-Then Focus tool in antimicrobial stewardship programs at a national level. It would also contribute to improving the use of antimicrobials.
Immunosuppressive drugs are necessary to avoid or reducethe risk of rejection of transplanted organs. The immunosuppression generatedmay result in these patients needing antibiotics and antivirals to beprescribed to them in conjunction with their immunosuppressants to avoidthe risk of infection. This has generated an increase in neutropenia inpatients treated with mycophenolate mofetil in combination with valganciclovir.The purpose of this study is to estimate the risk of neutropeniaattributable to combination treatment of mycophenolate mofetil with valganciclovirin patients with a transplanted liver.
This is a retrospective cohort study. It included patients whoreceived a liver transplant between 2012 and 2017 and who were treatedwith mycophenolate mofetil or with a combination of mycophenolatemofetil and valganciclovir. Minimum follow-up was 100 days posttransplantation.Children under 16 years of age and patients who diedduring follow-up were excluded. Binary logistic regression analysis wasused to determine the association of neutropenia with sex, age, diabetes,creatinine at baseline and at discharge, and concomitant treatment ofmycophenolate mofetil with valganciclovir.
