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The relationships among serum Apelin, Asymmetric- dimethylarginine (ADMA), N-terminal probrain natriureticpeptide (NT-proBNP) levels, and blood pressures in dialysis patients are not well known.
Age and sex matched 30 hemodialysis (HD), 30 peritoneal dialysis (PD) patients, and 20 healthy controls were recruited. Serum apelin-36, ADMA, NT-proBNP levels, and blood pressures of both patients and healthy controls were measured and compared.
Serum ADMA and Apelin levels in HD patients were significantly higher than in PD patients. In multiple regression analyses the predictors of higher serum apelin levels were higher BMI, higher ADMA and lower systolic blood pressure. The predictors of serum ADMA levels were being on HD. The predictors of serum NT-proBNP levels were lower serum albumin and higher systolic blood pressure.
Being on HD is a predictor of high ADMA levels. HD might be less effective on ADMA removal than PD. It seems that higher serum apelin levels related with lower sytolic blood pressure levels, whereas higher NT-proBNP levels related with higher sytolic blood pressure levels indicating potential roles as independent prognostic factors for systolic hypertension in dialysis patients.
Being on HD is a predictor of high ADMA levels. HD might be less effective on ADMA removal than PD. It seems that higher serum apelin levels related with lower sytolic blood pressure levels, whereas higher NT-proBNP levels related with higher sytolic blood pressure levels indicating potential roles as independent prognostic factors for systolic hypertension in dialysis patients.
The aim of this study is to evaluate the pattern of presentation, anatomic anomalies, and treatment outcomes in patients presenting with acute testicular torsion in a tertiary health institution in southeast Nigeria.
This was a prospective study of all consecutive patients with acute testicular torsion seen from January 2011 to November 2019 at our institution. Their demographic and clinical data were analyzed.
Thirty-one acute testicular torsion cases were seen during the study period. Mean age was 22.6 (±7.3) years. Two peaks of incidence were observed. These were in the 14-19-year and 20-25-year age groups. The left testis was more commonly affected than the right; 15 cases (48.4%) versus 13 cases (41.9%). Past history of intermittent torsion was seen in 48.4% of cases. Abdominal pain was the commonest associated symptom followed by vomiting; 20 (64.5%) and 11 (35.5%). Seven cases (22.6%) of acute torsion occurred during sleep. Delay in presentation and delay in surgical intervention were observed. Only 22.6% of patients presented within 6 h of onset of symptoms and only 32.3% were operated on within 6 h of presentation. Transverse lie of the testes was the most common intraoperative finding (36%). Testicular salvage rate was 87.1%.
Acute testicular torsion is a disease of young adults in southeast Nigeria. It is commoner on the left side with transverse lie being the most common predisposing factor. A new peak incidence in the 20-25-year age group is demonstrated. Late presentation is common but did not impact testicular loss in this study.
Acute testicular torsion is a disease of young adults in southeast Nigeria. It is commoner on the left side with transverse lie being the most common predisposing factor. A new peak incidence in the 20-25-year age group is demonstrated. Late presentation is common but did not impact testicular loss in this study.
Globally, low back pain (LBP) is now the leading cause of disability. Patients often have lumbar spine motion dysfunction (motion decrease/increase), and this may affect the lumbar lordosis (LL). Though the relationship between LL and LBP is controversial, it has immense clinical significance, because it serves as the basis of therapeutic exercises for treating and preventing LBP. An angular measure of LL that consistently detects even a small lordotic change (LC) would be considered reliable.
The consistency of some radiographic angles in detecting LC in a potential LBP disorder was evaluated, and LC fulcrum deducted.
In both normal (control) and spondylotic (test) lateral lumbosacral radiographs of both genders, LL was retrospectively measured using the following angular measures and sample sizes Lumbosacral angle (LSA, 125), Lumbosacral joint angle (LSJA, 115), Cobb angle (118), and Tangential radiologic assessment of lumbar lordosis (TRALL) angle (101). The angles' consistency in detecting intra-gender LC between control versus test was evaluated. The intervertebral disc (IVD) that sub-tended the most consistent angle represents the LC fulcrum. All cases were ≥17 years of age. Data was analyzed with IBM SPSS Statistics 23.0 (NY, USA); P < 0.05 was considered statistically significant.
LSJA detected slight intra-gender LC in both genders, LSA in males only, Cobb and TRALL angles in none. The IVD of L5/S1 sub-tended the LSJA and therefore represents the LC fulcrum.
LSJA is a reliable measure of lumbar LC in physical therapy of LBP, especially, the non-specific LBP disorders.
LSJA is a reliable measure of lumbar LC in physical therapy of LBP, especially, the non-specific LBP disorders.
Acute postoperative pain after myomectomy can impair patient function. Like all other postoperative pain, it is a challenge requiring solution, particularly in developing countries. BIRB 796 Ultrasound-guided transversus abdominis plane (TAP) block and wound infiltration (WI) are both known to be effective in managing postoperative pain. It is not certain if transversus abdominis plain block would be superior to wound infiltration. Aims It was hypothesized that the TAP block has similar analgesic effectiveness to wound infiltration.
This study was a randomized controlled trial involving, seventy-four (74) patients scheduled for myomectomy at the University of Benin Teaching Hospital Benin City, Nigeria under the subarachnoid block, which were randomized into TAP and WI group preoperatively. The ultrasound-guided bilateral TAP block group and wound infiltration group (subfascial and subcutaneous infiltration) each used 40 mL of 0.25% of plain bupivacaine to achieve postoperative analgesia. The time to first analgesic request, numerical pain rating scale (NRS) score at rest, and movement were assessed.