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30, 95% CI = 0.18-0.51). The availability of human resources and equipment was, however, not significantly associated with facility use. Poor geographic access could be a critical barrier to facility use among children in rural Zambia.Esophageal cancer (EC) is of public health significance as one of the leading causes of cancer death worldwide. Accurate staging, treatment planning and prognostication in EC patients are of vital importance. Recent advances in machine learning (ML) techniques demonstrate their potential to provide novel quantitative imaging markers in medical imaging. Radiomics approaches that could quantify medical images into high-dimensional data have been shown to improve the imaging-based classification system in characterizing the heterogeneity of primary tumors and lymph nodes in EC patients. In this review, we aim to provide a comprehensive summary of the evidence of the most recent developments in ML application in imaging pertinent to EC patient care. According to the published results, ML models evaluating treatment response and lymph node metastasis achieve reliable predictions, ranging from acceptable to outstanding in their validation groups. Patients stratified by ML models in different risk groups have a significant or borderline significant difference in survival outcomes. Prospective large multi-center studies are suggested to improve the generalizability of ML techniques with standardized imaging protocols and harmonization between different centers.Beekeeping in Africa has been practiced for many years through successive generations and along inherited patterns. Beekeepers continue to face challenges in accessing consistent and business-driven markets for their bee products. In addition, the honeybee populations are decreasing due to colony collapse disorder (CCD), fire, loss of bees in swarming, honey buggers and other animals, moths, starvation, cold weather, and Varoa mites. The main issues are related to un-controlled temperature, humidity, and traditional management of beekeeping. These challenges result in low production of honey and colony losses. The control of the environmental conditions within and surrounding the beehives are not available to beekeepers due to the lack of monitoring systems. A Smart Beehive System using Internet of Things (IoT) technology would allow beekeepers to keep track of the amount of honey created in their hives and bee colonies even when they are far from their hives, through mobile phones, which would curtail the ch application that interacts with the SBMaCS hardware to monitor and control the various parameters related to the beehives. U0126 supplier Finally, the SBMaCS PCB layout is also designed. SBMaCS will help beekeepers to successfully monitor and control some important smart beekeeping activities wherever they are using their mobile phone application.Human-carnivore conflicts are a major conservation issue. As bears are expanding their range in Europe's human-modified landscapes, it is increasingly important to understand, prevent, and address human-bear conflicts and evaluate mitigation strategies in areas of historical coexistence. Based on verified claims, we assessed costs, patterns, and drivers of bear damages in the relict Apennine brown bear population in the Abruzzo Lazio and Molise National Park (PNALM), central Italy. During 2005-2015, 203 ± 71 (SD) damage events were verified annually, equivalent to 75,987 ± 30,038 €/year paid for compensation. Most damages occurred in summer and fall, with livestock depredation, especially sheep and cattle calves, prevailing over other types of damages, with apiaries ranking second in costs of compensation. Transhumant livestock owners were less impacted than residential ones, and farms that adopted prevention measures loaned from the PNALM were less susceptible to bear damages. Livestock farms chronically damaged by bears represented 8 ± 3% of those annually impacted, corresponding to 24 ± 6% of compensation costs. Further improvements in the conflict mitigation policy adopted by the PNALM include integrated prevention, conditional compensation, and participatory processes. We discuss the implications of our study for Human-bear coexistence in broader contexts.In mobile edge computing (MEC), partial computational offloading can be intelligently investigated to reduce the energy consumption and service delay of user equipment (UE) by dividing a single task into different components. Some of the components execute locally on the UE while the remaining are offloaded to a mobile edge server (MES). In this paper, we investigate the partial offloading technique in MEC using a supervised deep learning approach. The proposed technique, comprehensive and energy efficient deep learning-based offloading technique (CEDOT), intelligently selects the partial offloading policy and also the size of each component of a task to reduce the service delay and energy consumption of UEs. We use deep learning to find, simultaneously, the best partitioning of a single task with the best offloading policy. The deep neural network (DNN) is trained through a comprehensive dataset, generated from our mathematical model, which reduces the time delay and energy consumption of the overall processormance of the proposed technique with high accuracy of the DNN in deciding offloading policy and partitioning of a task with minimum delay and energy consumption for UE. More than 70% accuracy of the trained DNN is achieved through a comprehensive training dataset. The simulation results also show the constant accuracy of the DNN when the UEs are moving which means the decision making of the offloading policy and partitioning are not affected by the mobility of UEs.

Antibiotic use in pregnant women at the national level has rarely been reported in China.

We aimed to investigate antibiotic prescriptions during pregnancy in ambulatory care settings in China.

Data of 4,574,961 ambulatory care visits of pregnant women from October 2014 to April 2018 were analyzed. Percentages of Antibiotic prescriptions by different subgroups and various diagnosis categories and proportions of inappropriate antibiotic prescriptions for different subgroups were estimated. Food and Drug Administration (FDA) pregnancy categories were used to describe the antibiotic prescription patterns. The 95% confidence intervals (CIs) were estimated using the Clopper--Pearson method or Goodman method.

Among the 4,574,961 outpatient visits during pregnancy, 2.0% (92,514 visits; 95% CI, 2.0-2.0%) were prescribed at least one antibiotic. The percentage of antibiotic prescriptions for pregnant women aged >40 years was 4.9% (95% CI, 4.7-5.0%), whereas that for pregnant women aged 26-30 years was 1.5% (95% CI, 1.