Dissingklint6167

We investigate a model formulated in terms of the network of discrete chemomechanical states of a ribosome during the elongation stage of translation. The model is analyzed using a combination of stochastic thermodynamic and kinetic analysis based on a graph-theoretic approach. We derive the exact solution of the corresponding master equations. We represent the steady state in terms of the cycles of the underlying network and discuss the energy transduction processes. We identify the various possible modes of operation of a ribosome in terms of its average velocity and mean rate of GTP hydrolysis. We also compute entropy production as functions of the rates of the interstate transitions and the thermodynamic cost for accuracy of the translation process.We study the joint probability distributions of separation R and radial component of the relative velocity V_R of particles settling under gravity in a turbulent flow. We also obtain the moments of these distributions and analyze their anisotropy using spherical harmonics. We find that the qualitative nature of the joint distributions remains the same as no-gravity case. Distributions of V_R for fixed values of R show a power-law dependence on V_R for a range of V_R; the exponent of the power law depends on the gravity. Effects of gravity are also manifested in the following ways (a) Moments of the distributions are anisotropic; degree of anisotropy depends on particle's Stokes number, but does not depend on R for small values of R. (b) Mean velocity of collision between two particles is decreased for particles having equal Stokes numbers but increased for particles having different Stokes numbers. For the later, collision velocity is set by the difference in their settling velocities.We investigate macroscopic two-fluid effects in magnetorheological fluids generalizing a one-fluid model studied before. In the bulk of the paper we use a model in which the carrier fluid, with density ρ_1, moves with velocity v_1, while the magnetic component (density ρ_2) and, therefore, the magnetization and the magnetic-field-induced relaxing strain field move with velocity v_2. In the framework of macroscopic dynamics we find, in particular, reversible dynamic and dissipative cross-coupling terms between the magnetization and the velocity difference. mTOR inhibitor Experiments to detect some of these cross-coupling terms are suggested. We also compare the results of the two-fluid model presented here with two-fluid models available for electrorheological fluids. In two appendices we discuss the simplifying assumptions made to arrive at the model used in this paper and we also outline how to detect potential deviations from this model.We consider two-dimensional turbulence in the presence of a condensate. The nondiagonal correlation functions of the Lagrangian accelerations are calculated, and it is shown that they have the same universality properties as the nondiagonal correlation functions of the velocity fluctuations.We apply time-dependent Ginzburg-Landau (TDGL) numerical simulations to study the finite frequency electrodynamics of superconductors subjected to an intense rf magnetic field. Much recent TDGL work has focused on spatially uniform external magnetic fields and largely ignores the Meissner state screening response of the superconductor. In this paper, we solve the TGDL equations for a spatially nonuniform magnetic field created by a point magnetic dipole in the vicinity of a semi-infinite superconductor. A two-domain simulation is performed to accurately capture the effect of the inhomogeneous applied fields and the resulting screening currents. The creation and dynamics of vortex semiloops penetrating deep into the superconductor domain are observed and studied, and the resulting third-harmonic nonlinear response of the sample is calculated. The effect of pointlike defects on vortex semi-loop behavior is also studied. This simulation method will assist our understanding of the limits of superconducting response to intense rf magnetic fields.We report intermittent large spiking events in a heterogeneous network of forced Josephson junctions under the influence of repulsive interaction. The response of the individual junctions has been inspected instead of the collective response of the ensemble, which reveals the large spiking events in a subpopulation with characteristic features of extreme events (EE). The network splits into three clusters of junctions, one in coherent libration, one in incoherent rotational motion, and another subpopulation originating EE, which resembles a chimeralike pattern. EE migrates spatially from one to another subpopulation of junctions with the repulsive strength. The origin of EE in a subpopulation and chimera pattern is a generic effect of distributed damping parameter and repulsive interaction, which we verify with another network of the Liénard system. EE originates in the subpopulation via a local riddling of in-phase synchronization. The probability density function of event heights confirms the rare occurrence of large events and the return time of EE as expressed by interevent intervals in the subgroup follows a Poisson distribution. The mechanism of the origin of such a unique clustering is explained qualitatively.This study focuses on the three-dimensional (3D) electrohydrodynamic flow instability between two parallel electrodes driven by unipolar charge injection with and without cross flow. Lattice Boltzmann method with a two-relaxation time model is used to compute flow patterns. In the absence of cross flow, the base-state solution is hydrostatic, and the electric field is one-dimensional. With strong charge injection and high electrical Rayleigh number, the system exhibits electroconvective vortices. Disturbed by perturbation patterns, such as rolling pattern, square pattern, and hexagon pattern, the flow develops corresponding to the most unstable mode. The growth rate and pattern transitions are studied using dynamic mode decomposition of the transient numerical solutions. The interactions between cross flow and electroconvective vortices lead to suppression and disappearance of structures with velocity components in the direction of cross flow, while the other components are not affected. Surprisingly, the transition from a 3D to a 2D flow pattern enhances the convective charge transport, marked by an increase in the electric Nusselt number.