Damsgaardrichter9296

[This corrects the article DOI 10.1021/acsomega.1c00505.].[This corrects the article DOI 10.1155/2021/6652017.].[This corrects the article DOI 10.1155/2020/7390321.].

Paradoxical increases in serum cortisol in the dexamethasone suppression test (DST) have been rarely observed in Cushing disease (CD). Its pathophysiology and prevalence remain unclear.

A 62-year-old woman with suspected CD showed paradoxical increases in cortisol after both 1-mg and 8-mg DST (1.95-fold and 2.52-fold, respectively). The initiation of metyrapone paradoxically decreased plasma adrenocorticotropic hormone (ACTH) levels and suppressed cortisol levels. Moreover, the pituitary tumor considerably shrank during metyrapone treatment.

The resected tumor tissue was enzymatically digested, dispersed, and embedded into Matrigel as 3D cultured cells. ACTH levels in the media were measured. In this tumor culture, ACTH levels increased 1.3-fold after dexamethasone treatment (

< 0.01) while control tumor cultures exhibited no increase in ACTH levels, but rather a 20% to 40% suppression (

< 0.05).

A cross-sectional, retrospective, multicenter study that included 92 patients with CD who underwnt from the majority of CD cases. The mechanisms exhibiting GC positive feedback in CD and the therapeutic approach for these patients remain to be investigated.This Letter demonstrates a novel, to the best of our knowledge, method to measure the fluence distribution of an intense short laser pulse based on the radiochromic effect. We discovered that an intense short laser pulse can induce the color reaction with a radiochromic film (RCF). Further, the net optical density of an irradiated RCF is proportional to the fluence of the incident laser pulse in a large range ($2 - 120\;\rm mJ/\rm cm^2$). This method supports a large detection area up to near square-meter scale by splicing multi-pieces of RCFs ($8 \times 10\;\rm inch^2$ each). The spatial resolution reaches as high as 60 lines/mm. It offers a thin-film ($\sim100\;\unicodex00B5\rm m$ thick), flexible, vacuum-compatible solution to intense short laser measurements, especially to laser facilities above petawatt, with beam sizes up to near square-meter scale, e.g., extreme light infrastructure.In this work, a novel, to the best of our knowledge, approach based on an x-ray thin lens imaging theory is proposed to predict the angular sensitivity responses of dual-phase-grating differential phase contrast (DPC) interferometers. see more Experimental validations have been performed to demonstrate the high accuracy of theoretical predictions using two different setups one with real source images and the other with virtual source images. This new sensitivity calculation method is helpful to optimize the DPC imaging performance of a dual-phase-grating system.An ultra-sensitive temperature sensor without sacrificing detection range is demonstrated on the silicon-on-insulator (SOI) platform using cascaded Mach-Zehnder interferometers (MZIs). The sensitivity enhancement is achieved by tailoring the geometric parameters of the two MZIs to have similar free spectral ranges (FSRs) but quite different sensitivities. The proposed sensor only needs single lithography for the sensing unit, without introducing negative thermo-optic coefficient (TOC) materials. The measured sensitivity is 1753.7 pm/°C from 27°C to 67°C, which is higher than any reported results on a silicon platform and about 21.9 times larger than conventional all-silicon temperature sensors.We present an erratum to our Letter [Opt. Lett.45, 3645 (2020)OPLEDP0146-959210.1364/OL.386605]. Labeling errors in one figure and corresponding sentence in the text are corrected. The corrections have no influence on the results and conclusions of the original Letter.Reconfigurable optical logic gates are developed through the design and optimization of a metallic grating with a colloidal nonlinear dielectric. The device has a structurally enhanced nonlinearity, improving power consumption and speed. Detailed design strategy and simulations for several common logic gates are provided. Using materials readily available in common CMOS processing technologies, the gates switch in sub-picosecond scales with a driving irradiance of around $200\; \rm MW/cm^2$.We report a watt-level mid-infrared (mid-IR) superfluorescent fiber source from $\rm Er^3 +$-doped ZBLAN fiber near 3 µm spectral range. With the power amplifier configuration, the mid-IR superfluorescent fiber source with power up to 1.85 W has been delivered successfully with slope efficiency about 18.6%. The experimental results may pave an avenue toward a high-power, high-temporal-stability superfluorescent source for versatile mid-IR applications.The photoluminescence (PL) efficiency of two-dimensional (2D) transition metal dichalcogenides (TMDs) is extremely low under high power excitation, limiting its potential in display and light-emission application. This arises from the much shorter lifetime of non-radiative recombination than radiative recombination, wherein photo-carriers tend to decay through non-radiative processes. Herein, a "molecular state" near the valence band is successfully introduced into the $\rm MoS_2$ monolayer to increase the density of radiative states and speed up the exciton relaxation. This reduces the recombination lifetime of excitons by two orders of magnitude and forms vigorous competition with non-radiative decays. As a consequence, dozens of times enhancement of PL in $\rm MoS_2$ monolayers under high excitation power ($\rm G\sim10^19\;\rm cm^- 2\cdot\rm S^- 1$) is realized. These results provide an effective method to improve PL efficiency under high injection levels for applications of 2D materials in light-emission industry.Freeform illumination design for extended sources is a very challenging but rewarding issue that can benefit a wide range of illumination systems. Here, we propose a method that can achieve compact and highly efficient illumination lenses by deconvolving the blur caused by the extent from light sources. We combine the illumination calculation with the mathematical model of spatially variant convolution and develop a direct computational scheme to calculate the blur kernel without approximations. Two design examples with high optical performances are presented to demonstrate the effectiveness of the proposed method.