Connorsykes6868

The growing demand for sustainable energy has led to in-depth research on hydrogen production from electrolyzed water, where the development of electrocatalysts is a top priority. We here report a controllable strategy for preparing the cobalt-nickel alloy nanoparticles encapsulated in nitrogen-doped porous carbon by annealing a bimetal-organic framework. The delicately tailored hierarchical Co2Ni@NC nanoparticles effectively realize abundant synergistic active sites and fast mass transfer for the oxygen evolution reaction (OER). Remarkably, the optimized Co2Ni@NC exhibits a small overpotential of 310 mV to achieve a current density of 10 mA cm-2 and an excellent long-term stability in alkaline electrolyte. Furthermore, the underlying synergistic effect mechanism of the Co-Ni model has been pioneeringly elucidated by density functional theory calculations.Chinese raspberry (Rubus chingii Hu) is a fruit valued for it's health benefits, which is indigenous to China. It is a great source of antioxidants. However, the fruit phytochemicals are poorly understood. Phenolics and carotenoids attract much attention for their antioxidant capability, and they dramatically change during fruit ripening, leading to the difference in color, flavor and medicinal components. In this study, we investigated the change of carotenoids, phenolics and antioxidant activity using spectrophotometry during four different ripening phases i.e. mature green (MG), green yellow (GY), yellow orange (YO) and red (RE). The major components of carotenoids, anthocyanins, ellagitannins and flavonols were identified and quantified by LC-MS/MS. As a result, five carotenoids (mainly β-Citraurin and its esters), six anthocyanins (mainly anthocyanins covalently linked to another flavonoid unit), methyl (S)-flavogallonate and rourinoside were first identified in Rubus. In contrast to other known raspberring fruit ripening, imparting the reddish color to ripe fruit.Biocompatible syntheses of Cu2O nanoparticles are relatively low compared to some other reported metal oxides due to their low stability and requiring more carefully controlled synthetic conditions. In the present study, the efficiency of three brown algae (Cystoseira myrica, Sargassum latifolium and Padina australis) extracts collected from the Persian Gulf was evaluated in the biosynthesis of Cu2O nanoparticles. A fast and simplified synthesis of Cu2O nanoparticles with average size between 12 and 26 nm was successfully achieved through an eco-friendly method using the aqueous extracts of Sargassum latifolium and Cystoseira myrica. Whereas, under the same reaction conditions using Padina australis extract no Cu2O nanoparticles were produced, and unexpectedly, the results approved the formation of spindle shaped CaCO3 with average sizes of 1-2 μm in length and 300-500 nm in width. Structure, morphology and composition of the as-prepared products were characterized by XRD, FT-IR, UV-vis, TEM and FESEM analysis. This work confirms that the biomolecules present in algae have the ability to affect particle size, morphology, composition, and physicochemical properties of the synthesized particles. The Cu2O nanoparticles prepared in this study were stable and exhibited efficient antibacterial and anticancer activity. This biosynthesis technique can be valuable in environmental, biotechnological, pharmaceutical and medical applications.In our ongoing research for the discovery of new constituents with antimyeloma activity, we investigated 15 compounds present in the aerial parts of Leontodon saxatilis for their cytotoxic potential against NCI-H929, U266, and OPM2 cell lines. One of the isolated compounds displayed a new natural product and was identified as 5-feruloyl-2α-hydroxyquinic acid after LC-MS and NMR experiments. Of the remaining compounds, cichoric acid and three flavone glycosides, apigenin 4'-O-β-d-glucoside, luteolin 7-O-β-d-glucoside and luteolin 4'-O-β-d-glucoside, showed moderate cytotoxic activity, whereas the effects of two aglyones apigenin and luteolin were more pronounced. Though the cytotoxic potential of the two aglycones (against other cell lines) was reported in various studies, our work moreover showed that cooccurrence of these two compounds with similar components of lower activity led to comparable results and at the same time minimized the damage of healthy fibroblast cells. Thus, our work could be a starting point for additional studies on the synergistic effect of similar components against myeloma cell lines.Three novel metal-tiron (4,5-dihydroxy-1,3-benzenedisulfonic acid disodium salt) and other pillared ligand bpy (4,4'-bipyridyl)-centered coordination polymers of the formulae [Cd(tiron)(bpy)2(H2O)2]·0.5(H2O), 1, [Co3(tiron-bpy)2(bpy)(H2O)8]·(H2O)2, 2, and [Ba2(tiron-bpy)2(H2O)4][solvent], 3, were successfully synthesized under hydrothermal conditions. The as-synthesized materials were well characterized by complimentary techniques such as single-crystal X-ray diffraction, powder X-ray diffraction, Fourier-transform infrared spectroscopy and thermogravimetric analysis techniques. The as-synthesized coordination polymers of 1 and 2 featured 1D chains, while 3 shows a layered structure. Co-based 2 shows linear trinuclear Co(ii) ions and these Co(ii) ions have antiferromagnetic interactions among themselves. The structure of 1 features a zig-zag chain formed by the linkage between monodentate tiron ligands and octahedral Cd(ii) ions, interconnected by a twisted bpy ligand, 2 shows a linear chain constructed from corner-sharing trinuclear octahedral Co(ii) ions and coordinated with a tridentate tiron-bpy adduct ligand, whereas 3 shows nona-coordinated Ba(ii) ions sharing edges with other Ba(ii) ions and connected by hexadentate tiron-bridged structures resulting in a layered structure. In 2 and 3, the bpy nitrogen attacks at the ortho position of the tiron ligand and forms an in situ ligand adduct. The central metal ions show an octahedral geometry in 1 (Cd(ii) ions) and 2 (Co(ii) ions), but nona-coordination of Ba(ii) ions in 3. The short interatomic interactions in the crystal structures were evaluated by mapping the Hirshfeld surface process using pseudo-mirrored 2D fingerprint plots. The major short interatomic interactions H⋯H, O⋯H and C⋯H cover the Hirshfeld surfaces.A recyclable and efficient heterogeneous, green catalyst based on the synthesis of Keggin-type polyoxometalate (H3PMo12O40) and vitamin B1 analogue 3-ethyl-5-(2-hydroxyethyl)-4-methylthiazol-3-ium (HEMT), i.e., [HEMTH]H2[PMo12O40] was prepared. Oxa-Pictet-Spengler cyclization of arylethanols and aldehydes were catalyzed to afford various substituted isochromans in moderate conditions with excellent yields using dimethyl carbonate (DMC) as a green solvent. Furthermore, this protocol was applicable in a gram-scale reaction, and the catalyst could be recycled eight times without significant loss of activity.The concave-cube FePt nanoparticles (NPs) with shape-anisotropy and element-distribution-anisotropy were annealed under a high magnetic field (HMF). The NPs underwent spheroidization and phase transformation during the annealing process. The HMF hardly affected the spheroidizing process of NPs, but obviously facilitated the disorder-order transition of the L10-phase. The L10-phase content, ordering degree, and the coercivity of annealed NPs increased with enhancing the HMF strength. Those results indicated that the nucleation of the L10-phase and ordering diffusion of Fe/Pt atoms were promoted by the HMF.In this work, gold nanorods embedded in ultra-thick silica shells with radial mesopores (AuNR/R-SiO2) were successfully synthesized in an ethanol/water solution. By optimizing the concentration of CTAB and the volume of ethanol, a shell thickness up to 83 nm was realized. Taking advantage of the ultra-thick silica shell, AuNR/R-SiO2 exhibited ultra-high thermal stability-could retain the integrity and photothermal effects even after 800 °C thermal annealing, providing inspiring sights into the application under some extreme conditions. Selleckchem Pidnarulex After continuous irradiation for twenty times, the photothermal effects of AuNRs coated with R-SiO2 still remained perfect without performance degradation and shape change. Besides, abundant mesopores could effectively improve the photothermal conversion efficiency of AuNRs. AuNR/R-SiO2 exhibited an outstanding loading capacity up to 2178 mg g-1 with doxorubicin (DOX) as the model drug, and the release behaviors could be nicely controlled by acidity and near-infrared (NIR) laser to achieve the "On-demand" mode. In vitro experiments showed that AuNR/R-SiO2 were biocompatible and easy to be internalized by HeLa cells. In addition, due to the ultra-thick silica shell, the effect of the combined chemo-photothermal therapy using AuNR/R-SiO2/DOX was significantly enhanced, showing a higher therapeutic efficiency than single chem- or photothermal therapy. It was worth noting that AuNR/R-SiO2 are effective and promising for drug delivery and tumor therapy.The aggregation of dyes is a common phenomenon in solutions, particularly concentrated solutions, which seriously affects the dyeing and printing processes. In this study, the effects of alkylamine solvents on the reactive dye aggregation behavior in highly concentrated solutions was studied. Typical cases were conducted with two slightly toxic and environmentally friendly solvents, namely diethanolamine (DEA) and triethanolamine (TEA), and two reactive dyes, namely C. I. Reactive Red 218 (R-218) and C. I. Reactive Orange 13 (O-13). Aggregation states were studied by ultraviolet-visible (UV-Vis) absorption spectroscopy, Gaussian-peak-fitting method and fluorescence spectroscopy. The results showed that both the additives DEA and TEA could reduce the dye aggregation because the solvents, DEA and TEA, can break the iceberg structure and allow easy entry of the molecules into the dye aggregates. Also, the disaggregation caused by DEA was higher as compared with TEA, which may be caused by the weaker hydrogen bond and the relatively smaller steric hindrance effects of DEA. The schematic of disaggregation between R-218 and DEA was also discussed. For R-218, the dimers were disaggregated to monomer, while the higher-ordered aggregates were disaggregated to trimers and dimers for O-13. Moreover, physical properties such as viscosity and surface tension of the solutions were measured. This investigation is instructive for the further dyeing progress with organic bases in the textile industries.Applying electric and magnetic fields on water molecules confined in carbon nanotubes (CNTs) has important applications in cell biology and nanotechnology-based fields. In this work, molecular dynamics (MD) simulations were carried out to examine the probable phase transitions in confined water molecules confined in (14,0) CNTs at 300 K by applying different electric and magnetic fields in the axial direction. We have also studied some thermodynamics and structural properties of the confined water molecules in the different fields. Our results showed that the confined water molecules experience. Some phase (shape) transitions from the pentagonal to twisted pentagonal, spiral and circle-like shapes by increasing the electric field from 104 (V m-1) to 107 (V m-1). Also, applying the magnetic field with different intensities has small effects on the pentagonal shape of confined water molecules but applying the highest magnetic field (300 T) makes the pentagonal shape more ordered. These phase transitions have not been reported before.