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Dec and the formation of stable lipid solutions of CIN.Dec. Altering formulation pH to more acidic conditions, therefore stabilises drug-ILs formed using weakly acidic lipophilic counterions, and is a viable method to promote formulation stability via inhibition of disproportionation of some drug-ILs.

A transition plan refers to post-high school goals identified and developed on the basis of the needs, strengths, skills, and interests of students. A significant factor for achieving successful transition planning is parental involvement. In this regard, many studies in Saudi have explored the barriers to effective collaboration between schools and parents.

From the perspective of special education teachers, the study examined parental participation in transition planning for students with intellectual disability enrolled in schools in Saudi Arabia. Furthermore, parental challenges were discussed.

A questionnaire was used to collect data from 91 special education teachers. The t-test, confirmatory factor analysis, and Cronbach's alpha were used for statistical analysis.

Results indicated that parents lacked participation in transition planning for several reasons, such as lack of time and lack of knowledge about transition. However, the study found that schools did not proactively seek parental participation nor provide substantial guidance about transition services to enable parents to provide a meaningful contribution to planning.

Limitations and implications for future research and practice are discussed.

Limitations and implications for future research and practice are discussed.

longitudinal effects of cognitive rehabilitation in Rett Syndrome (RTT) have been poorly investigated and the mechanisms do not appear to have been described in detail.

the aim of this study was to examine the effects of cognitive rehabilitation with eye-tracker technology on attention, choice behaviours and language over a 2-year period in patients with RTT.

28 participants with RTT, ranging from age 4-22 years old (M = 13.85 years, SD = 5.89), received 30 min of cognitive rehabilitation with eye-tracker for 3 days a week over a 1-month for 2 years. They then underwent cognitive assessment to evaluate attention, choice, language and global functioning in four specific times before cognitive rehabilitation (T1), after six months of cognitive rehabilitation (T2), six months after the second cognitive rehabilitation phase (T3) and at the end of the third cognitive rehabilitation phase (T4).

patients with RTT show long-term improvements in seconds of attention and number of choice behaviours, with barely any improvement in global functioning. No improvement in language was found.

this is the first study aimed at examining longitudinal effects of cognitive rehabilitation in patients with RTT, demonstrating a linear improvement across time in attention and choice.

this is the first study aimed at examining longitudinal effects of cognitive rehabilitation in patients with RTT, demonstrating a linear improvement across time in attention and choice.

This study sought to assess the effect of reading augmented reality (AR) books on salivary cortisol levels in hospitalized pediatric patients compared to reading a standard children's book.

This was a randomized, two-period, cross-over trial in hospitalized children aged 7-11 years. AR books currently in the market were used as intervention. Complete block randomization was used to randomize the order of the intervention. Children allocated to the 'AR-first' group received the book, a tablet and were left to interact independently with the technology for an hour. After a 48 -h wash-out period, children received a standard book. 'Standard-book-first' group received only the standard book and after wash-out received the tablet and the AR book. Salivary cortisol and a validated visual analogue scale (VAS) for psychological stress were assessed at the beginning and at the end of each intervention.

A total of 29 children were recruited in the study. One was lost during follow up. Cortisol levels decreased after the AR intervention (P = 0.019). selleck chemicals llc Nevertheless, the decrease was not greater than the one associated to reading the standard book. VAS scores increased after the AR intervention (P < 0.001).

There is evidence of order and sequence effects that might explain results. First assessment of AR-based interventions on stress. Results justify further research.

There was no evidence that reading AR books diminished cortisol levels more than reading a standard book. AR-books improved VAS score for psychological stress compared to a standard book.

There was no evidence that reading AR books diminished cortisol levels more than reading a standard book. AR-books improved VAS score for psychological stress compared to a standard book.The lattice Boltzmann method (LBM) has recently emerged as an efficient alternative to classical Navier-Stokes solvers. This is particularly true for hemodynamics in complex geometries. However, in its most basic formulation, i.e. with the so-called single relaxation time (SRT) collision operator, it has been observed to have a limited stability domain in the Courant/Fourier space, strongly constraining the minimum time-step and grid size. The development of improved collision models such as the multiple relaxation time (MRT) operator in central moments space has tremendously widened the stability domain, while allowing to overcome a number of other well-documented artifacts, therefore opening the door for simulations over a wider range of grid and time-step sizes. The present work focuses on implementing and validating a specific collision operator, the central Hermite moments multiple relaxation time model with the full expansion of the equilibrium distribution function, to simulate blood flows in intracranial aneurysms. The study further proceeds with a validation of the numerical model through different test-cases and against experimental measurements obtained via stereoscopic particle image velocimetry (PIV) and phase-contrast magnetic resonance imaging (PC-MRI). For a patient-specific aneurysm both PIV and PC-MRI agree fairly well with the simulation. Finally, low-resolution simulations were shown to be able to capture blood flow information with sufficient accuracy, as demonstrated through both qualitative and quantitative analysis of the flow field while leading to strongly reduced computation times. For instance in the case of the patient-specific configuration, increasing the grid-size by a factor of two led to a reduction of computation time by a factor of 14 with very good similarity indices still ranging from 0.83 to 0.88.

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