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OBJECTIVE To investigate serum levels of vitamin A and E in pregnant women in Huai'an and evaluate their nutritional status. METHODS Totally 2824 cases of pregnant women were chosen from the Huai'an Maternal and Child Health-Care Center during January 2017 to May 2018. The serum level of vitamin A and vitamin E in the blood was detected by high performance liquid chromatography(HPLC). RESULTS The serum level of vitamin A was(0. 39±0. 08) mg/L, the overall abnormal rate was 12. 3%. The serum level of vitamin E was(13. 28±4. 67) mg/L, the overall abnormal rate was 3. 7%. Vitamin A level were positively correlated with age and dysarteriotony. Vitamin E level were also positively correlated age, dysarteriotony and appetite. CONCLUSION The abnormal of vitamin A is mainly lack, the abnormal of vitamin E is mainly excessive.OBJECTIVE To understand the iodine nutrition status of adults in Xinjiang Uygur Autonomous Region under the effective control of iodine deficiency disease. METHODS Using stratified cluster random sampling method, in the district to determine water iodine median less then 10 μg/L and ≥10 μg/L of urban and rural areas, a total of 10 survey points, deals from the collecting water deals of extracting water iodine content detection. Adults over 18 years old were randomly selected from 30 households at each survey site to carry out a survey on dietary iodine intake, and the contents of dietary salt iodine and adult urine iodine were tested. RESULTS The median iodine content in water in Xinjiang Uygur Autonomous Region was 4. 4(2. 3, 13. 6)μg/L. The median iodine content of household salt was 27(24, 30) mg/kg. The median urinary iodine content in adults was 168(103, 259)μg/L. The average dietary iodine intake of adults in the region was 312 μg/d. CONCLUSION The water iodine content in the environment outside Xinjiang Uygur Autonomous Region is relatively low, and the iodine nutritional status and dietary iodine intake of adults are generally at the appropriate level. However, urban adults with relatively low water iodine content and good economic status have a higher risk of iodine deficiency. Iodized salt is the main source of dietary iodine for adults in Xinjiang Uygur Autonomous Region. Adults in poorer rural and urban areas rely more heavily on iodized salt.OBJECTIVE To assess the intake of thiamine, riboflavin and niacin and estimate the association between the adequacy of intake of those three B-vitamins and risk factors among older Chinese adults. METHODS A total of 3222 adults aged 65 and above with completed dietary data were derived from the 2015 survey of China Nutritional Transition Cohort Study 2015. The total subjects. Dietary data was recorded by three consecutive days with 24-hour recalls. The intake of those three B-vitamins were assessed by comparing with Chinese dietary thiamine, riboflavin and niacin reference intakes. The food sources of three vitamins were analyzed. Multivariate Logistic regression was used to estimate adjusted odds ratios for factors associated with the inadequacy of intake of those three vitamins. RESULTS The median daily intake of thiamine, riboflavin and niacin was 0. 8, 0. 7 and 12. 8 mg in males, and 0. 7, 0. 6 and 10. 9 mg in females, respectively. Adults aged 80 and above and living in the southern regions were more likely to have inadequate thiamine intake than adults aged 65-79 and living in northern regions, respectively. Adults had inadequate intake of riboflavin were more likely to be living in a village and adults with lower education levels than adults living in a city and adults with higher education levels. In males, adults had inadequate intake of niacin were more likely to be 80 years and above, with lower education levels, living in the northern regions, living in a village and with the lowest income. In females, adults had inadequate intake of niacin were more likely to be with lower education, living in northern regions and living in a village. KN-62 price CONCLUSION About 80% adults were at the risk of the inadequate intake of thiamine and riboflavin in China. Age, education, income, regions and areas of residence were associated with the intake of thiamine, riboflavin and niacin.OBJECTIVE To longitudinally analyze the associations between physical activity, sedentary time and dietary intake levels with waist circumference and abdominal obesity among Chinese reproductive women. METHODS In the five rounds of "China health and nutrition survey" in 2004, 2006, 2009, 2011 and 2015, 2951 women aged 15-49 years old who participated in at least two rounds of surveys were selected as research objects. Physical activity and sedentary time data were collected by questionnaire survey, and food consumption data were collected by 24-hour retrospective method for 3 consecutive days. Analysis of variance was used to analyze the time difference of continuous variables. Chi-square test was used to analyze the differences in time distribution of classified variables. Linear multilevel model was used to analyze the relationships between waist circumference and different levels of physical activity, sedentary time and dietary intake. Logistic multilevel model was used to analyze the risk of abdominal obebesity was 1. 32(P less then 0. 001). There was no statistical significance in physical activity level with waist circumference and abdominal obesity. CONCLUSION Television time and dietary factors(insufficient intake of dark color vegetables and high consumption of pastry) are independent risk factors for abdominal obesity among Chinese reproductive women. Besides strengthening physical activity, the prevention of abdominal obesity in reproductive women should also strengthen the intervention measures to reduce TV time and promote appropriate dietary behaviors(increasing dark color vegetable intake and reducing pastry intake).OBJECTIVE To investigate the expression of S100β protein and mRNA of Schwann cells(SC) in sciatic nerves of 2, 5-hexanedione(HD) intoxicated rats. METHODS Nine-week old SPF male Wistar rats were administered at daily dosing of 100 and 300 mg/kg by intraperitoneal injection for continuous 8 weeks(five times every week). Age-matched control rats received an equivalent volume of normal saline. Ten rats in each group were sacrificed and sciatic nerves were excised for S100β determination, with excised sciatic nerves from another three rats for morphological observation through electron microscope. At the end of the exposure, the other 8-week treated animals were allowed to naturally recover for 8 weeks and sciatic nerves were excised at the end of the test. S100β protein contents were determined by immunohistochemistry method, and mRNA expression was observed by real-time quantitative polymerase chain reaction(PCR). RESULTS HD intoxication with 300 mg/kg was associated with severe neurological deficits of paralysis in hindlimbs, accompanied with evident movement gait abnormalities for 100 mg/kg dosage.

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