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There is increasing evidence that lifestyle factors play an important role in the development of hypertension and dyslipidemia. However, existing research usually evaluated these risk factors individually (such as physical activity, smoking, drinking, obesity and so on), rather than joint evaluation. The aim of this study was to quantify the association between a combination of a healthy lifestyle and the risk of hypertension and dyslipidemia.

A healthy lifestyle score was created based on 4 factors never smoking, moderate to high-intensive physical activity, no alcohol drinking, and normal body mass index. We calculated the healthy lifestyle score using the cumulative number of health factors for each individual. Also, a multivariate analysis was used to assess the relationship between healthy lifestyle and hypertension and dyslipidemia. Among 6446 participants, 650 (10.08%) had lowest healthy lifestyle score (0) and 627 (9.72%) had highest healthy lifestyle score (4), respectively. The adjustment model indicated that participants with the highest score (score 4), which integrated the four lifestyles, had significantly lower ORs for hypertension compared with the lowest score (score 0) (0.21; (95%CI 0.10, 0.43P-trend< 0.001)). Selleck TTK21 In the adjustment models, compared with lowest healthy lifestyle score, the ORs of highest healthy lifestyle score was 0.17; (95%CI 0.07, 0.42P-trend<0.001) for dyslipidemia.

Hypertension and dyslipidemia were negatively correlated with healthy lifestyle score. Interventions with healthy lifestyle to reduce hypertension, dyslipidemia and promote population health are warranted.

Hypertension and dyslipidemia were negatively correlated with healthy lifestyle score. Interventions with healthy lifestyle to reduce hypertension, dyslipidemia and promote population health are warranted.

The prevalence of type 2 diabetes (T2D) in Italy is increasing and cardiovascular disease (CVD) represents the leading cause of death in this population. CAPTURE was a multinational, multicentre, non-interventional, cross-sectional study assessing the prevalence of CVD, atherosclerotic CVD (AsCVD) and CVD subtypes among patients with T2D, across 13 countries. Here we report the results from Italy.

Overall, 816 patients with T2D (median age, 69 years [interquartile range 62-75]; median duration of diabetes, 11.2 years [interquartile range 5.7-18.7]) were recruited during routine clinical visits at secondary care centres in Italy between December 2018-September 2019. The prevalence of CVD was estimated at 38.8%, largely accounted for by AsCVD (33.1%). The most prevalent CVD subtype was coronary heart disease (20.8%), followed by carotid artery disease (13.2%). Most patients (85.9%) were prescribed oral glucose-lowering agents (GLAs), particularly biguanide (76.7%). Insulin use was higher in patients with CVD (41.3%) than in patients without CVD (32.9%). Sodium-glucose co-transporter-2 inhibitors (SGLT2is) and glucagon-like peptide-1 receptor agonists (GLP-1 RAs) were prescribed to 20.2% vs 14.6%, and 14.5% vs 16.6% of patients with CVD compared to those without CVD, respectively.

The results show that, in Italy, more than one in three patients with T2D attending secondary care centres have CVD, 85% of whom have AsCVD, yet only a minority are treated with SGLT2is and GLP-1 RAs, in discordance with the recommendations of current national and international guidelines.

The results show that, in Italy, more than one in three patients with T2D attending secondary care centres have CVD, 85% of whom have AsCVD, yet only a minority are treated with SGLT2is and GLP-1 RAs, in discordance with the recommendations of current national and international guidelines.

Visceral adiposity index (VAI), an indicator of visceral fat, is associated with metabolic health and arterial stiffness. However, studies correlating VAI and stroke are limited. This study aimed to explore the association between VAI and incident stroke in the Chinese population.

We retrospectively analysed the data of 9127 individuals enrolled in the China Health and Retirement Longitudinal Study. The first survey of the study was conducted during 2011-2012 and the individuals were followed up until Survey 4 (2017-2018). Multivariable-adjusted Cox regression models were used to evaluate the association between VAI and stroke. The mean age of the study population was 59.3±9.5 years and 4938 (54.1%) participants were women. During the median follow-up of 5.2 [1.0-7.0] years, 833 (9.1%) participants developed stroke, and the cumulative incidence of stroke increased with increasing quartiles of VAI (8.6%, 8.7%, 9.2%, and 10.0%). Compared to those in the first quartile of VAI, individuals in the fourth quartile had an increased risk of stroke (adjusted hazard ratio, 1.45; 95% CI, 1.15-1.75). The results were stable in several sensitivity analyses.

Our findings suggest a positive association between VAI and incident stroke in the Chinese population.

Our findings suggest a positive association between VAI and incident stroke in the Chinese population.

The renin-angiotensin system (RAS), which is a key mediator of cardiovascular homeostasis, has two main axes. The classic one, including angiotensin-converting enzyme (ACE) and Angiotensin (Ang) II, promoting vasoconstriction, and the "alternative" one, including ACE2 and Ang1-7, with opposed actions to AngII. ACE2 has been identified as the main receptor of SARS-CoV2, whereby it enters the cells, leading to the downregulation of surface ACE2 and RAS tissue unbalance. Given that diabetes is associated with an increase in COVID-19 severity and death, we aimed at evaluating RAS expression in patients with type 1 diabetes (T1D).

This is a case-control study comparing 39 T1D patients to 33 controls, with a median age of 29 and 32 years, and no comorbidities. ACE and ACE2 gene expression was assessed in peripheral blood mononuclear cells. T1D patients had higher ACE expression and circulating AngII, which were related to glucose levels. T1D patients had lower ACE2 expression. However, ACE2 expression was also related to the sex of participants, being higher in the female group. T1D women did not show the same increase of ACE2 expression that was seen in control women.

T1D promotes the increase of ACE, AngII, and ACE/ACE2, which might contribute to the higher cardiovascular risk, as well as to severe tissue injury induced by SARS-CoV2 in these patients. The ratio ACE/ACE2 does not differ between men and women with T1D, which might explain why CVD or COVID-19 do not show substantial gender differences in these patients.

T1D promotes the increase of ACE, AngII, and ACE/ACE2, which might contribute to the higher cardiovascular risk, as well as to severe tissue injury induced by SARS-CoV2 in these patients. The ratio ACE/ACE2 does not differ between men and women with T1D, which might explain why CVD or COVID-19 do not show substantial gender differences in these patients.

This study aims to perform a detailed analysis of the validity and reliability of the Turkish version of the Person-Centered Perioperative Nursing Scale (PCPON).

Methodological and descriptive study.

This study was conducted online between December 2020 and February 2021, with 240 nurses working in the surgical wards of private hospitals in Istanbul, Turkey. Individual Characteristics Questionnaire and PCPON were used to collect data. Cronbach Alpha reliability analysis and Confirmatory Factor Analysis (CFA) were applied using R Project software to the data.

As a result of the analysis, all corrected item correlation values for compassionate interaction, respect, comfort, sharing information, and expertise were found to be positive following the original factors structure of the scale. According to reliability analysis statistics, Cronbach's Alpha coefficients were calculated as 0.781, 0.758, 0.780, 0.750 and 0.808 for compassionate interaction, respect, comfort, sharing information, and expertise subented nurse-patient relationship.

To explore whether an aromatherapy product, QueaseEASE, could be used to supplement standard postoperative nursing care for children experiencing discomfort from postoperative nausea and vomiting (PONV) in a pediatric outpatient surgical setting.

Evidence-based practice project resulting in a prospective, descriptive research design.

English-speaking pediatric outpatient surgical patients 8 to 17 years of age were evaluated for symptoms of discomfort during the postoperative phase of care, using the Baxter Animated Retching Faces (BARF) scale and offered the QueaseEASE aromatherapy product. A postoperative phone call was made the next business day to inquire about use of product at home.

Thirty-one patients rated their BARF scores as four or greater and were qualified to use the aromatherapy pod. Twenty-four patients (77.4%) demonstrated a positive response to the aromatherapy, as evidenced by a BARF score improvement of 2 or more points upon reassessment. Fourteen of the 27 patients (51.8%) contacted at home during the postoperative phone call stated continued use of the aromatherapy pod, and 100% of the families were satisfied with this adjunct therapy.

Aromatherapy resulted in an improvement in self-reported nausea scores in a pediatric surgical outpatient population and was a family satisfier. Further research is recommended.

Aromatherapy resulted in an improvement in self-reported nausea scores in a pediatric surgical outpatient population and was a family satisfier. Further research is recommended.

To explore Swedish registered nurse anesthetists' (RNAs') different ways of understanding difficult airway algorithms.

A qualitative study design, using a phenomenographic approach, was chosen to describe variations in RNAs' understanding of difficult airway algorithms.

Individual interviews were conducted with eighteen RNAs working at three hospitals in Sweden. The data were analyzed using a qualitative method.

Three ways of understanding algorithms were identified (1) Algorithms constitute a plan not communicated at the clinic; (2) Algorithms constitute a shared plan to improve teamwork; (3) Algorithms constitute a plan for how to think and work systematically.

According to the RNAs, airway management algorithms should be discussed more openly at the workplace. RNAs expressed their desire to have a shared algorithm and to use it as a tool during team simulations. Airway algorithms were seen as constituting a plan for how to think and work systematically to improve patient safety.

According to the RNAs, airway management algorithms should be discussed more openly at the workplace. RNAs expressed their desire to have a shared algorithm and to use it as a tool during team simulations. Airway algorithms were seen as constituting a plan for how to think and work systematically to improve patient safety.

This study aimed to determine the impact of surgical approach on postoperative recovery, quality of life, and satisfaction level in patients undergoing uniportal or multiportal video-assisted thoracoscopic surgery (VATS) or open thoracotomy.

This prospective study included patients who underwent open thoracotomy, uniportal VATS, or multiportal VATS in a tertiary Hospital between January 1, 2019 and May 1, 2021.

Recovery was evaluated at postoperative 24th, 48th, and 72nd hours, and 1 month using the Postoperative Recovery Index (PoRI); quality of life was evaluated using the Short Form 36 (SF-36) at postoperative 1 month; and patient satisfaction\was assessed with visual analog scale (VAS) at postoperative 72nd hours and at 1 month.

Of 215 patients screened, 163 patients met the inclusion criteria. Women had higher PoRI values than men at postoperative 24th, 48th, and 72nd hours. Open thoracotomy was associated with higher PoRI values, lower SF-36 scores (except social functioning), and lower satisfaction at postoperative 72nd hours compared to VATS.