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The top-ranked criterion considered by male and female students was physical attractiveness and education respectively. Gender difference in mate selection preferences was found to be significant in the study. Though, gender difference was significant in age, education, financial status, physical appearance, physical attractiveness, and profession criterion; however, the gender difference was not significant in character, in-law family's education, in-law family's social approval, religion, region, and residential status. Mate selection criteria considered by Bangladeshi students are explained by the social homogamy theory. The study would help Bangladeshi people to be aware of their mate selection in their own Bangladeshi culture.Previous research has established the lack of motivation by primary education students vis-à-vis the acquisition of the necessary key competencies compulsory in the Spanish school curriculum and this is closely linked to poor academic performance on the part of the aforesaid students. Based on this current educational reality, we present a quantitative study regarding the perception of students after the implementation of a new gamified experience in the classroom such that it integrates, for the first time and jointly, the benefits of gamification (Deterding et al., 2011a; Deterding & Zagal, 2018) with interdisciplinary methodologies (Candel, 2018; Cruz-Pichardo & Cabero-Almenara, 2020; Flores-Aguilar, 2019) and technology-enhanced transmedia narratives (Scolari 2018a, 2018b; Jenkins, 2003; Scolari 2018a, 2018b). This integrative and innovative proposal was implemented in a primary school in Valencia (Spain) between October 2019 and February 2020. The research is designed based on survey-type studies, employemic performance.
In a previous work, a pure crystalline titanium dioxide nanoparticles (TiO
NPs) were synthesized by green synthesis technique using Aloe vera leaves extract as reducing agent. In this work, we are aiming to investigate the potential of the novel greenly synthesized TiO
NPs as a nano-drug delivery system for the anticancer drug, doxorubicin (Dox).
The cytotoxicity of the synthesized TiO
NPs was tested on two cell lines; normal human skin fibroblasts (HSF) and breast adenocarcinoma cells (MCF-7). Then, Dox was loaded to both TiO
NPs (Dox- TiO
NPs) and liposomes (Dox-Lip). The loaded nanoparticles were characterized by TEM, FTIR, encapsulation efficiency, particle size and zeta potential measurement. Moreover, in vitro drug release was studied. Ehrlich tumor-bearing mice were used to study the anticancer activity of Dox- TiO
NPs, Dox-Lip, and aqueous Dox solution. Tumor volume, survival rate, and histopathological alterations were compared in all groups.
Dox was successfully loaded to both liposomes and TiO
NPs with an encapsulation efficiency of 77% and 65%, respectively. The particle size of Dox-TiO
NPs, and Dox-Lip was 14.53 nm, and 103 nm, respectively. The cumulative Dox released from TiO
NPs and liposomes after 4 h was 18 and 46%, respectively.Dox-Lip and Dox-TiO
NPs resulted in the highest degree of tumor growth inhibition with 100% and 83% of treated animals remained alive, respectively.
The greenly synthesized TiO
NPs were proved to be as effective as liposomes in enhancing the anticancer activity of Dox.
The greenly synthesized TiO2NPs were proved to be as effective as liposomes in enhancing the anticancer activity of Dox.Cistanche deserticola has been historically used in traditional Chinese medicine for supplementing kidney (yang) function, benefiting blood and essence, and moistening intestines in order to pass stool. Its host, Haloxylon ammodendron, is an important pioneer plant used for windbreaks and sand dune fixation, which are strategies used for the control desertification. For a long time, it has been considered that C. deserticola can only parasitize H. ammodendron. In this study, morphological identification, gene barcoding identification and inoculation experiment were carried out, we finally found that C. deserticola can also parasitize Atriplex canescens. A. canescens is a species of Chenopodiaceae with a wide range of adaptability. Compared with H. ammodendron, it has more biomass and a wider range of ecological adaptability, making it more suitable for the industrial production of C. deserticola. In addition, we also found that the concentration of active components was higher in C. deserticola parasitized on A. Captisol Hydrotropic Agents inhibitor canescens than in those parasitized on H. ammodendron; this finding further suggests that the application of C. deserticola on a larger scale warrants further exploration.The synthesis of copper nanoparticles (CuNPs) using Wrightia tinctoria (Wt) R.Br extract is defined in this article as being convenient, environmentally friendly, and non-toxic. UV-visible spectrophotometry, FT-IR, XRD, particle size analyser, SEM-EDAX and TEM methods were used to describe the physicochemical properties of Wt extract mediated synthesized CuNPs (Wt-CuNPs). The Wt-CuNPs synthesized was found to be monodispersed and spherical, with an average size of 15 nm. Gas chromatography and mass spectrometry (GC-MS) research revealed that the Wt R.Br plant extract contains various phytochemical compounds. The properties of Wt-CuNPs were verified by the findings of characterization tests. Via in silico molecular docking experiments with established targets, the underlying mechanisms of cytotoxicity against breast cancer and larvicidal behaviour against Aedes aegypti of Wt-CuNPs were investigated. Interestingly, in vitro cytotoxicity studies showed 50% cell death (IC50) of Wt-CuNPs treated MCF-7 cells and Vero Cells (Kidney epithelial cells) were displayed at 119.23 μg.mL-1 and 898.75 μg.mL-1, respectively. Also, Wt-CuNPs showed least LC50 and LC90 values for larvicidal activity against A. aegypti were of 32.10 μg.mL-1 and 21.70 μg.mL-1, respectively. Furthermore, Wt-CuNPs is found to be less toxic and biocompatible in haemolytic assays. The findings clearly showed that biosynthesized Wt-CuNPs have been used as a possible anticancer and larvicidal agent, as well as being environmentally friendly.