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Industries have made claims on the effectiveness of a disinfection procedure in reducing COVID-19 transmission. This procedure is usually performed by automated dispersion of disinfectant on individuals when they go through a booth. This Health Technology Assessment (HTA) report is a systematic review that synthesizes the evidence on the efficacy and safety of using these booths and provides recommendations to the Ministry of Health to facilitate decision-making regarding the relevance of using this technology.
A systematic literature review was performed using Pubmed, Web of Science, INAHTA and GIN databases, from inception to June 4, 2020. Three independent reviewers selected eligible studies then extracted and synthesized the evidence. The synthesis was submitted to a multidisciplinary group of experts to provide recommendations.
Two scientific papers and a Malaysian HTA report were included in data synthesis. In light of the resources consulted, spraying disinfectants on humans in booths is not effective and can be toxic. Disinfectants are intended for use on surfaces, not on living tissue and spraying disinfectants on the outside of the body does not kill the virus inside an infected person's body. Furthermore, this procedure may increase the risk of neglecting other effective measures.
It is recommended to prohibit the use of disinfection booths in all structures.
It is recommended to prohibit the use of disinfection booths in all structures.
Since its declaration in december 2019, a novel coronavirus, the SARS-CoV-2 was rapidly responsible for a major pandemic. COVID-19 is mainly manifested by respiratory symptoms,however, digestive manifestations have been reported, raising the hypothesis of the viral digestive tropism.
Specify the digestive manifestations due to the SARS-CoV-2, and their impact on the disease prognosis and describe the COVID-19 effect in patients with underlying digestive disease.
Ageneral review of the medical literature was conducted via Medline® database, through various combinations of the following keywords SARS-CoV-2, COVID-19, gastrointestinal tract, digestive system, inflammatory bowel diseases, liver, liver injury, chronic liver disease, neoplasms. The most relevant articles were selected.
The SARS-CoV-2 tropism for the digestive tract has been confirmed by the identification of the enterocyte as a target cell of the virus. Viral particles and RNA detection in stool of infected patients has raised the potential for feco-oral transmission of the virus. Gastrointestinal manifestations were frequent and may even be revealing or isolated. Diarrhea was the most characteristic symptom. Frequent liver involvement is associated with a more severe form of the disease. Patients with digestive cancer and chronic liver disease are at risk for a severe form of SARS-CoV-2 infection.
The clinician is required to know this type of manifestations in order to limit the delay in diagnosis and to better assess the prognosis.
The clinician is required to know this type of manifestations in order to limit the delay in diagnosis and to better assess the prognosis.
Diagnosis of SARS-CoV-2 infection is a major public health issue. In a context of limited diagnostic capacity with the reference technique (real-time RT-PCR), many manufacturers have developed rapid diagnostic tests (RDTs). Although very promising in theory, these tests have raised many questions. This article is a rapid review that synthesizes data regarding different types of available RDTs, their performance, their limits and their potential indications in Tunisia as proposed by a multidisciplinary group of experts.
A literature review was carried out on the websites of international organizations, governmental bodies and on INAHTA database, completed by a search of relevant scientific articles up to 1 June 2020. The synthesis of the data was submitted to a panel of experts to propose recommendations for the Tunisian context.
RDTs based on the detection of antigens and antibodies have sensitivity and specificity related issues. Few validation reports are published in the scientific literature. Pending more evidence on their performance and validity, several international organizations recommend their use only for research purposes. TDRs based on antibody detection are not appropriate for the early diagnosis of COVID-19. However, validated and specific tests could provide complementary diagnostic information to reference tests.
Pending further evidence, the panel recommends the use of RDTs mainly for research purposes at the community level.
Pending further evidence, the panel recommends the use of RDTs mainly for research purposes at the community level.
For frontline healthcare workers (FHW) who are working with Coronavirus Disease-19 (COVID-19) patients, PPE is currently considered as one of the most discussed topics. Recommendation from international organizations concerning the use of PPE are broadly consistent but equipment use is not. No previous studies examined the use of PPE in Tunisia.
Evaluate the availability of personal protective equipment(PPE) in addition to the reality and perception regarding personal safety in workplace.
We carried out a cross-sectional survey from 15th April to 5th May 2020 across public and private institutions in Tunisia. Linsitinib concentration A 33-item structured questionnaire was developed and administered to FHWs.
We received 723 responses. We found that there was a likely overuse of PPE in addition to a high rate of side effects caused by PPE.
Additional training in PPE use might be useful, and sessional work should be considered to decrease the side effects associated with PPE use.
Additional training in PPE use might be useful, and sessional work should be considered to decrease the side effects associated with PPE use.
The number of cases of SARS-Cov-2 contamination in Setif (Algeria) is constantly increasing, representing to date nearly 10% of all cases recorded throughout the country.
To evaluate the preventive measures taken by the service sector companies against the spread of the virus.
A survey of 115 service sector companies was carried out in the prefecture of Setif (Algeria). The data was collected using a pre-established questionnaire completed with one of the officials of the company and by direct observation.
A high prevalence (42%) of women put on leave was found. Physical meetings were held in 38% of the companies, hydroalcoholic solution was available for employees in 85% and for customers only in 4%. In more than 70% of cases, disinfection of surfaces, floors and door handles took place frequently. Safety distance between employees and customers was respected in 88%, between employees in 66% and between customers in 63% of the companies. The wearing of a mask by all, the majority, some and none of the employees was observed in respectively 15%, 17%, 39% and 29% of the companies.
