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vention had a 0.28% reduction. Those assigned to the control group had a 0.16% reduction in HbA1c. Conclusions A novel mobile-delivered DPP achieved significant weight loss reductions for up to 1 year compared with usual care. This type of intervention reduces the risk of overt diabetes without the added barriers of in-person interventions. Clinicaltrial Clinicaltrials.gov NCT03865342; https//clinicaltrials.gov/ct2/show/NCT03865342.Background Although mobile health (mHealth) has the potential to transform health care by delivering better outcomes at a much lower cost than traditional health care services, little is known about mHealth adoption by hospitals. Objective This study aimed to explore the determinants of mHealth adoption by hospitals using the technology-organization-environment (TOE) framework. Methods We conducted an interviewer-administered survey with 87 managers in Chinese public hospitals and analyzed the data using logistic regression. Results The results of our survey indicate that perceived ease of use (β=.692; P less then .002), system security (β=.473; P less then .05), top management support (β=1.466; P less then .002), hospital size (β=1.069; P less then .004), and external pressure (β=.703; P less then .005) are significantly related to hospitals' adoption of mHealth. However, information technology infrastructure (β=.574; P less then .02), system reliability (β=-1.291; P less then .01), and government policy (β=2.010; P less then .04) are significant but negatively related to hospitals' adoption of mHealth. Conclusions We found that TOE works in the context of mHealth adoption by hospitals. In addition to technological predictors, organizational and environmental predictors are critical for explaining mHealth adoption by Chinese hospitals.Background The prevalence of social media (SM) use among youth and young adults suggests SM as an appropriate platform for study recruitment from this population. Previous studies have examined the use of SM for recruitment, but few have compared different SM platforms, and none to our knowledge have attempted to recruit cigarillo users. Objective The purpose of this study is to examine the effectiveness of different SM platforms and advertisement images for recruiting 14-28-year-old cigarillo users to complete a cigarillo use survey. Methods We obtained objective data for advertisement impressions for a 39-week SM recruitment campaign. Advertisements were targeted by age, geography, and interests. Advertising effectiveness was defined as the percentage of approved surveys per advertising impression. Chi-square tests were performed comparing the effectiveness of different advertisement images and platforms. Results Valid survey completers (n=1,089) were predominately older (25-28 years old, n=839, 77%). Five hundred and sixty-eight (52%) identified as male, n=335 (31%) as African American, and n=196 (18%) as Hispanic. Advertisements delivered via Facebook/Instagram were more effective than Twitter; n=311 (0.03%) vs. n=661 (0.02%), Χ2(1, N=4,026,453) = 21.45, P less then .001. Across platforms, ads featuring exclusively an image of cigarillos were more effective (n=397, 0.06%) than ads with images of individuals smoking (n=254, 0.02%), individuals not smoking (n=239, .02%), and groups not smoking (n=82, 0.01%), Χ2(3, N = 4,026,453) = 133.73, P less then .001. Conclusions The campaign was effective in recruiting a diverse sample representative of important racial/ethnic categories. Advertisements on Facebook were more effective than Twitter. Including a cigarillo image was consistently the most effective advertisement design and should be considered by others recruiting cigarillo users via SM.Background Using cell phones to support healthcare (mHealth) has been shown to improve health outcomes across a multitude of health specialties and across the world. Exploring mHealth user experiences can aid in understanding the 'how and why' an intervention was impactful. The Mobile Alliance for Maternal Action (MAMA) was a free maternal mHealth text messaging (SMS) service offered to pregnant women in Johannesburg, South Africa with a goal of improving maternal, fetal, and infant health outcomes. We conducted focus group discussions with MAMA users to learn about their experiences with the program. Objective To gather opinions of participants of the MAMA maternal mHealth service regarding current healthcare atmosphere, intervention use, and intervention feedback. Methods Fifteen prenatal and postnatal women attending public antenatal and postnatal care sites in central Johannesburg who were receiving free maternal health text messages (MAMA) participated in three focus group discussions. Predefined discussion topics included personal background, health care system experiences, text message program recruitment, acceptability, participant experiences and feedback. Hormones antagonist Results Feedback regarding experiences with the health system was mixed with a few reports of positive experiences, and many more reports of negative experiences such as long waiting times, understaffed facilities and poor service. Overall acceptability for the maternal text message intervention was high. Participants reflected that messages were timely, written clearly and felt supportive. Participants reported sharing messages with friends and family. Conclusions These findings suggest maternal mHealth interventions, delivered through text messages can provide timely, relevant, useful and supportive information to pregnant women and new mothers especially in cases of mistrust of the healthcare system.Background Social media has recently provided a remarkable means of delivering health information broadly and in a cost-effective way. Despite its benefits, some difficulties are encountered in attempting to influence the public to change their behavior in response to social media health messages. Objective This study aimed to explore the factors that affect individuals' acceptance of using social media as a tool for receiving health awareness messages and adapting such content accordingly by developing a smart health awareness message framework. Methods A quantitative method was adapted to validate the hypotheses and proposed framework through the development of a survey based on the technology acceptance model with the extension of other constructs. The survey was distributed on the web to 701 participants from different countries via Qualtrics software, it generated 391 completed questionnaires, and the response rate was 55.8% (391/701). Results Of the 391 respondents, 121 used social media platforms often during the week, with a percentage of 30.