Holckbradford1017

To perform a comprehensive evidence synthesis to summarize the impact of frailty on health outcomes in patients with chronic kidney disease (CKD).

Systematic reviews and meta-analysis.

Electronic searches in PubMed, Embase, Web of Science, CNKI, VIP, CBM, and Wanfang Database were performed. The methodological quality was evaluated using the Newcastle Ottawa Scale (NOS).

Patients with chronic kidney disease (CKD).

Potential clinical outcomes due to frailty.

Eighteen cohort studies incorporating a total of 22,788 participants were included. The overall risk of bias was low. The median reported prevalence of frail and prefrail individuals with CKD was 41.8% (range 2.8-81.5%) and 43.9% (range 19.1-62.7%), respectively. Prefrailty and frailty related to mortality indicated an increased hazard ratio (HR), with a pooled HR of 1.68 [95% confidence interval (CI) 1.46-1.94; P<.001] and 1.48 (95% CI 1.21-1.81; P<.001), respectively. Prefrailty and frailty related to hospitalization with the pooled HR/-cause hospitalization, and falls. Therefore, frailty should be routinely assessed among patients with CKD to prevent poor prognosis, reduce fatality rate, and provide evidence to support future targeted interventions. However, because of the limited amount of information currently in the literature, additional prospective studies are needed to explore the role of prefrailty in predicting adverse outcomes for patients with CKD.

To examine the associations between dietary patterns in midlife and likelihood of future healthy ageing in Chinese older adults.

Prospective population-based study.

We included 14,159 participants aged 45-74years who were free from cancer, cardiovascular disease, or diabetes at baseline (1993-1998) from the Singapore Chinese Health Study.

Dietary intakes in midlife were assessed by a validated food frequency questionnaire at baseline. Diet quality was scored according to the alternate Mediterranean diet (aMED), the Dietary Approaches to Stop Hypertension (DASH) diet, the alternative Healthy Eating Index (AHEI)-2010, overall plant-based diet index (PDI), and healthful plant-based diet index (hPDI). Healthy ageing was assessed at the third follow-up visit (2014-2016), which occurred about 20years after the baseline visit, and was defined as the absence of 10 chronic diseases, no impairment of cognitive function, no limitations in instrumental activities of daily living, no clinical depression at screenierence to various healthy dietary patterns at midlife is associated with higher likelihood of healthy ageing at later life.

Despite mobility impairments, many residents have physical, cognitive, and psychosocial resources that should be promoted. The aim was to summarize the current evidence on chair-based exercise (CBE) interventions for nursing home residents.

Systematic review registered with Prospero (registration number CRD42018078196).

Nursing home residents in long-term care.

Five electronic databases were searched (MEDLINE, Embase, CINAHL, Cochrane Central, and PsycINFO) from inception until July 2020. Title, abstract, and full-text screening as well as quality assessment with the Downs and Black checklist was done by 2 independent reviewers. Studies were eligible if they (1) were conducted in nursing home residents, (2) included participants with a mean age of 65years, (3) had at least 1 treatment arm with seated exercises only, (4) included active or inactive controls, (5) measured outcomes related to physical and/or cognitive functioning and/or well-being, and (6) controlled studies or single-group pre-post designitive functions as well as well-being in nursing home residents. Task-specific multicomponent CBE appears to be best for improving different domains of physical and cognitive functioning. More high-quality trials are needed.

The results indicate that CBE interventions may improve physical and cognitive functions as well as well-being in nursing home residents. Task-specific multicomponent CBE appears to be best for improving different domains of physical and cognitive functioning. More high-quality trials are needed.Produced water (PW) and spent oil-based wastewaters are some of the largest mineral oil wastewaters produced. Due to the high toxicity of hydrocarbons, several countries set stringent discharge limits and its treatment is compulsory before discharge. In this work, biological treatment of mineral oil wastewaters coupled with the production of bacterial lipids is demonstrated in sequential batch airlift reactors (SBAR). Gambogic Bcl-2 inhibitor Two SBAR (2 L working volume) were used for treatment of PW and lubricant-based wastewater (LW), inoculated with Alcanivorax borkumensis SK2 (SBARAb+PW) and Rhodococcus opacus B4 (SBARR.o+LW), respectively. A total petroleum hydrocarbon removal (TPH) efficiency up to 96% and 80% were achieved for SBARAb+PW and SBARR.o+LW, respectively. Intracellular lipids production in SBARAb+PW increased when lower TPH/N ratios and higher feast stage duration were applied (up to 0.74 g g-1 cell dry weight (CDW)), whereas in SBARR.o+LW higher lipids production was observed for higher TPH/N ratios (0.94 g g-1 in CDW). Triacylglycerols (TAG) were the main intracellular lipid accumulated in both SBARAb+PW and SBARR.o+LW operations, while wax ester (WE) production was only observed extracellularly in the SBARAb+PW.Air pollution generates hazardous pollutants that have resulted in safety, health, and other welfare issues of food animals. This paper reviewed scientific research advancement in food animal welfare-related air pollution based on 219 first-hand research publications in refereed journals (referred to as "RPs") over the past nine decades. Scientific studies in this area began in the 1930s. The number of RPs has increased significantly with each decade from the 1960s to the 1980s, then decreased until the 2010s. Twenty-six countries have contributed to this multidisciplinary research. About 52% of the studies were conducted in the U.S. and U.K. Research activities have surged in China since the 2010s. On-farm discoveries in air toxicity that resulted in animal death or injury were all from observational studies. About 75% of the studies were experimental and conducted primarily under laboratory conditions. Ammonia (NH3) was the main pollutant in 59% of the RPs, followed by dust, hydrogen sulfide (H2S), bacteria and endotoxins, carbon dioxide (CO2), carbon monoxide (CO), silo gas, sulfur dioxide (SO2), and odor.