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However, there are aspects of the pathology that still need to be clarified to establish better actions to control and prevention. This paper reviews the current knowledge about Cp. as foodborne pathogen, the pathophysiology of NE, and recent findings on potential strategies for its control.Wind barrier structures on railway bridges are installed to mitigate the wind effects on travelling trains; however, they cause additional wind loads and associated aerodynamic effects on the bridge. An innovative concept was developed for a wind barrier structure in this study that used a glass-fibre-reinforced polymer (GFRP) that may deform properly when subjected to a crosswind. Such deformation then allows for wind to pass, therefore reducing the wind loads transferred to the bridge. Wind tunnel experiments were conducted on a 1/40-scale train and bridge models with the proposed GFRP barrier subjected to airflow at different speeds up to 20 m/s. The side-force and overturning-moment coefficients of both the train and the bridge were evaluated to characterise the aerodynamic effects. The results show that favourable side-force and overturning-moment coefficients of the train were provided by wind barriers taller than 10 cm. The aerodynamic coefficients of the train were not significantly affected by the airflow speeds; meanwhile, the overturning-moment coefficient of the bridge decreased with the increase in airflow speed due to smaller wind resistance of the barrier after deformation. A numerical analysis was conducted on both the reduced- and full-scale models of the train-barrier-bridge system and the results supported the findings obtained from the wind tunnel experiments.

We investigated the effectiveness of a 12-week SaBang-DolGi walking exercise program on the physical and mental health of menopausal women and aimed to provide the basic data needed to develop health promotion programs for the active and healthy aging of menopausal women.

The participants comprised 40 women aged 50-65 years who were divided into two randomly selected groups in training sessions (exercising group, n = 21 and control group, n = 19). A physical (grip, muscle and endurance) test and mental health test (simple mental health test II) were conducted using questionnaires with the aim of examining subjects' physical and mental health before and after exercise.

After the intervention, the participants experienced positive changes in the physical dimension, with significant enhancements particularly in mental well-being and menopause-related health and subdomains. Controlled and regular exercise for 12 weeks was significantly correlated with a positive change in vitality and mental health.

We found that the SaBang-DolGi walking exercise program helps to promote the physical and mental health of menopausal women who are exposed to the various stresses and depressions that accompany physical deterioration; the program was found to encourage active and healthy aging.

We found that the SaBang-DolGi walking exercise program helps to promote the physical and mental health of menopausal women who are exposed to the various stresses and depressions that accompany physical deterioration; the program was found to encourage active and healthy aging.Therapeutic response is evaluated using the diameter of tumors and quantitative parameters of 2-[18F] fluoro-2-deoxy-d-glucose positron emission tomography (FDG-PET). Tumor response to molecular-targeted drugs and immune checkpoint inhibitors is different from conventional chemotherapy in terms of temporal metabolic alteration and morphological change after the therapy. Cancer stem cells, immunologically competent cells, and metabolism of cancer are considered targets of novel therapy. Accumulation of FDG reflects the glucose metabolism of cancer cells as well as immune cells in the tumor microenvironment, which differs among patients according to the individual immune function; however, FDG-PET could evaluate the viability of the tumor as a whole. find more On the other hand, specific imaging and cell tracking of cancer cell or immunological cell subsets does not elucidate tumor response in a complexed interaction in the tumor microenvironment. Considering tumor heterogeneity and individual variation in therapeutic response, a radiomics approach with quantitative features of multimodal images and deep learning algorithm with reference to pathologic and genetic data has the potential to improve response assessment for emerging cancer therapy.Aiming at the pollution and ecological hazards of the lake sediments of Bosten Lake, once China's largest inland lake, the spatial distribution and influencing factors of the potentially-toxic elements in its surface sediments were studied with the methods of spatial autocorrelation, two-way cluster analysis, and redundancy analysis. Finally, based on the background value of potentially-toxic elements extracted from a sediment core, a comprehensive evaluation of the risk of these potentially-toxic elements was conducted with the potential-ecological-risk index and the pollution-load index. With data on the grain size, bulk-rock composition, and organic matter content, this comprehensive analysis suggested that with the enrichment of authigenic carbonate minerals, the content of potentially-toxic elements exhibited distinctive characteristics representative of arid regions with lower values than those in humid region. All potentially-toxic elements revealed a significant spatial autocorrelation, and high-value areas mainly occurred in the middle and southwest. The content of potentially-toxic elements is related to Al2O3, K2O, Fe2O3, TiO2, MgO, and MnO, and the storage medium of potentially-toxic elements mainly consists of small particles with a grain size less then 16 μm. The pollution load index (PLI) for the whole lake due to the potentially-toxic elements was 1.31, and the surface area with a PLI higher than 1 and a moderate pollution level accounted for 87.2% of the total lake area. The research conclusions have an important scientific value for future lake ecological quality assessment and lake environment governance.