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790). However, in patients with DBT, MR detected significantly more additional sites of malignancy in dense compared to non-dense breasts (p=0.017). There was no difference in false-positive MR exams (p=0.470) for DM versus DBT. For both DM and DBT cohorts, higher MR background parenchymal enhancement was associated with higher false-positive (p=0.040) but no significant difference in true-positive exams.

Among patients with DBT imaging at cancer diagnosis, women with dense breasts appear to benefit more from preoperative MR than non-dense women. In women imaged only with DM, MR finds additional malignancy across all breast densities.

Among patients with DBT imaging at cancer diagnosis, women with dense breasts appear to benefit more from preoperative MR than non-dense women. In women imaged only with DM, MR finds additional malignancy across all breast densities.

To investigate whether the carotid bifurcation angle as assessed by computed tomographic angiography (CTA) is associated with anterior circulation ischemic stroke (ACIS) in young patients.

Thirty patients (mean age 41.5±6years) with known acute ACIS (group 1) were compared to 30 control patients (mean age/ 41.2±6years) (group 2) with similar demographic variables in this retrospective study. Geometrical characteristics of bilateral carotid bifurcation were obtained by CTA. The ICA bifurcation (ICAB) angle, the carotid central bifurcation (CCB), and the carotid bifurcation wall (CBW) angle among the ICA, CCA, and ECA were measured. Carotid artery angle measurements were compared between group 1 and group 2. The comparison of pathological (ACIS) and non-pathological (non-ACIS) carotid sides in group 1 was performed as well.

All the measured angles (AMA) of group 1 were higher than group 2 (p˂0.05). In patients with left-sided ACIS, AMA on the left side were higher than the right side (p˂0.05), this was more prominent in males (p˂0.05). All angles measured were found to be higher in ipsilateral ACIS (p˂0.05). The left CCB angle values had a significant effect on ischemic stroke (p˂0.05). Daporinad manufacturer Male patients had more left-sided ACIS (p˂0.05). Plaque development in ICA was found statistically significant in group 1 compared to group 2 (p˂0.05).

Carotid artery geometry may play an important role in the development of ischemic events in young patients, especially in men and, also in patients with left-sided stroke. The left CCB angle had a significant effect on ACIS.

Carotid artery geometry may play an important role in the development of ischemic events in young patients, especially in men and, also in patients with left-sided stroke. The left CCB angle had a significant effect on ACIS.

Automatic and detailed segmentation of the prostate using magnetic resonance imaging (MRI) plays an essential role in prostate imaging diagnosis. Traditionally, prostate gland was manually delineated by the clinician in a time-consuming process that requires professional experience of the observer. Thus, we proposed an automatic prostate segmentation method, called SegDGAN, which is based on a classic generative adversarial network model.

The proposed method comprises a fully convolutional generation network of densely con- nected blocks and a critic network with multi-scale feature extraction. In these computations, the objective function is optimized using mean absolute error and the Dice coefficient, leading to improved accuracy of segmentation results and correspondence with the ground truth. The common and similar medical image segmentation networks U-Net, FCN, and SegAN were selected for qualitative and quantitative comparisons with SegDGAN using a 220-patient dataset and the public datasets. The commonly used segmentation evaluation metrics DSC, VOE, ASD, and HD were used to compare the accuracy of segmentation between these methods.

SegDGAN achieved the highest DSC value of 91.66%, the lowest VOE value of 15.28%, the lowest ASD values of 0.51mm and the lowest HD value of 11.58mm with the clinical dataset. In addition, the highest DSC value, and the lowest VOE, ASD and HD values obtained with the public data set PROMISE12 were 86.24%, 23.60%, 1.02mm and 7.57mm, respectively.

Our experimental results show that the SegDGAN model have the potential to improve the accuracy of MRI-based prostate gland segmentation. Code has been made available at https//github.com/w3user/SegDGAN.

Our experimental results show that the SegDGAN model have the potential to improve the accuracy of MRI-based prostate gland segmentation. Code has been made available at https//github.com/w3user/SegDGAN.

Various components of Metabolic Syndrome (MetS) have been studied in general population, but few among patients undergoing hemodialysis (HD). This study aims to assess the metabolic profiles and to estimate the prevalence of MetS among patients with End-Stage Renal Failure (ESRF) undergoing HD.

Patients undergoing HD during October 2016-August 2017 in three General Hospitals in Aceh - Indonesia were included in the study. MetS was defined according to the modified NCEP-ATP III criteria for South Asians.

The overall prevalence of MetS was 50.2%. Male patients have higher MetS prevalence (58.3%) than female (41.7%). MetS was only associated with gender and history of diabetes, and not with other demographic variables. Alteration central obesity was the most common metabolic abnormality among the patients (57.2%), followed by hypertension (30.7%), diabetes (30%), raised triglycerides (27.4%) and reduced HDL (23.7%). Pre-metabolic syndrome was found in 48.3%, leaving only 1.4% of patients free from metabolic abnormality.

Half of the patients undergoing HD in Indonesia suffered from MetS and almost half had pre-metabolic syndrome. High rate of metabolic abnormalities in patients with ESRF requires intensive examination and collaboration between nephrologists and endocrinologists to prevent the deterioration of patients' condition during HD.

Half of the patients undergoing HD in Indonesia suffered from MetS and almost half had pre-metabolic syndrome. High rate of metabolic abnormalities in patients with ESRF requires intensive examination and collaboration between nephrologists and endocrinologists to prevent the deterioration of patients' condition during HD.

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