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To investigate factors related to the rotational stability of an acrylic toric intraocular lens (IOL).

Four ophthalmic surgical sites in Japan.

Prospective case series.

Subjects were 120 eyes of 120 patients undergoing phacoemulsification and implantation of a toric IOL (AcrySof IQ, Alcon Laboratories, Inc.). At 1 hour after surgery, the area of continuous curvilinear capsulorrhexis (CCC) was measured, and the state of anterior capsule coverage on the IOL optic (total on or partial on) was recorded. The toric IOL axis orientation was assessed at the end of surgery, 1 hour, 1 week, 1 month, and 6 months after surgery. Multiple regression analysis was performed to explore any clinical factors relevant to IOL rotation from the end of surgery to 6 months postoperatively. The explanatory variables included age, anterior chamber depth before surgery, axial length, type of corneal astigmatism (with-the-rule, against-the-rule, or oblique), area of CCC, state of anterior capsule overlap on IOL optic (total coverage vs. partial coverage), and surgical sites (surgeons).

The multiple regression analysis indicated that anterior capsule overlap on the IOL optic was the only variable associated with IOL rotation at 6 months postoperatively (P = .0482). The mean absolute rotation at 6 months was 1.96 ± 1.81 degrees in the total on group and 3.79 ± 3.12 degrees in the partial on group (P = .0004).

Rotational stability of a single-piece, acrylic toric IOL was better in eyes with total anterior capsule coverage than partial anterior capsule coverage on the IOL optic.

Rotational stability of a single-piece, acrylic toric IOL was better in eyes with total anterior capsule coverage than partial anterior capsule coverage on the IOL optic.

To evaluate refractive and visual outcomes of single-step transepithelial photorefractive keratectomy (transPRK) in the treatment of mixed astigmatism with the use of an aberration-neutral profile and large ablation zone.

Nicolaus Copernicus University and Oftalmika Eye Hospital, Bydgoszcz, Poland DESIGN Retrospective, observational case series.

This study included 48 eyes of 39 patients who underwent transPRK to correct mixed astigmatism and completed the 3-year follow-up. Procedures were performed with an Amaris 750S excimer laser using an aberration-neutral profile and optical zone of 7.2 mm or more.

Preoperatively, mean spherical manifest refraction (MRSE) was +1.37 ± 0.98 diopters (D) (0.25 to 4.0 D), and astigmatism was -4.0 ± 0.76 D (-2.25 to -6 D). Three years post-surgery it was -0.17 ± 0.26 D and -0.41 ± 0.44 D, respectively. Attempted spherical equivalent correction within ±0.50 D was achieved in 45 eyes (94%), and cylindrical correction in 34 (71%). Preoperative corrected distance visual acuity (CDVA) was 20/20 or better in 38 eyes (79%), and postoperative uncorrected (UDVA) was 20/20 or better in 29 eyes (60.0%). No eye had lost two or more Snellen lines of CDVA while 3 eyes (6%) gained 2 or more lines. In 4 eyes (8%) haze of low intensity was observed at the periphery, with scores between 0.5 to 1, and only one eye getting a score of 2 in 0-4-degree scale.

Mixed astigmatism correction with large-ablation-zone transPRK provided good results for efficacy, safety, predictability, and visual outcomes in a 3-year follow up.

Mixed astigmatism correction with large-ablation-zone transPRK provided good results for efficacy, safety, predictability, and visual outcomes in a 3-year follow up.

To compare the repeatability of ocular biometry measured with the Lenstar LS 900, IOLMaster 700 and Anterion, and its impact on predicted intraocular lens (IOL) power SETTING Tertiary eye-care facility in South India.

Prospective, observational and cross-sectional.

Eyes diagnosed with cataract had three consecutive scans on each biometers. The repeatability was assessed using the within-subject standard deviation (Sw), test-retest repeatability (TRT) and coefficient of variation (COV). The agreement was evaluated with the intraclass correlation (ICC). The IOL power was calculated with the Barrett Universal II formula.

The study comprised of 127 eyes of 76 patients. The repeatability of all parameters for a given device were excellent (ICC > 0.9, low COV and Sw). The agreement of the parameters between the biometers was very good (range from 0.93 to 0.99). The predicted IOL power differed statistically between the devices (p<0.05) but the difference was clinically insignificant between the three biometers (ICC > 0.99 for repeat calculation of IOL power).

All the biometers included in the study had good to excellent repeatability of biometry parameters. The agreement of the predicted IOL power was excellent between the three optical biometers.

All the biometers included in the study had good to excellent repeatability of biometry parameters. The agreement of the predicted IOL power was excellent between the three optical biometers.

To compare the effects of phacoemulsification surgery (PE) using an anterior chamber maintainer (ACM) and conventional PE using an ophthalmic viscosurgical device (OVD) on corneal endothelial cells.

Department of Ophthalmology, Celal Bayar University, Manisa,Turkey.

Prospective randomized controlled trial.

This study included 100 eyes of 97 patients undergoing PE. Eyes in the OVD group (n=50) underwent conventional PE, while eyes in the ACM group (n=50) underwent PE using an ACM. NBQX Endothelial cell density (ECD), coefficient of variation (CV), hexagonality (HEX) and non-contact central corneal thickness (CCT) measurements were performed by specular microscopy (SM) before and at 1, 3, and 6 months after PE.

Mean age was 64.7 ± 10.6 in the OVD group, 64.0 ± 12.6 in the ACM group (p>0.05). The groups did not differ significantly in terms of preoperative ECD, CV, HEX, and CCT or total PE time (p>0.05 for all). ECD was significantly lower in the ACM group compared to the OVD group at postoperative 1, 3, and 6 months (p=0.002, p=0.002, p=0.001). Similarly, ECD loss compared to preoperative value was greater in the ACM group at all postoperative time points (p=0.003, p=0.001, p=0.001). CV increased and HEX decreased in both groups postoperatively (p>0.05 for both). CCT showed a transient increase of less than 10 μm at postoperative 1 month in both groups (p=0.296).

PE with ACM was associated with greater corneal ECD loss compared to conventional PE. ACM should not be used during PE in patients with limited corneal endothelial reserve.

PE with ACM was associated with greater corneal ECD loss compared to conventional PE. ACM should not be used during PE in patients with limited corneal endothelial reserve.

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