Mallingrichard8019

Background Autogenous bone graft is the gold standard for repair of bone defects. However, osteoprogenitor stem cells are suggested as an alternative treatment. Aims To quantitatively compare bone formation in autogenous bone graft and tissue-engineered graft using digital radiography densitometry software in canine alveolar cleft model. Setting and Design This experimental study on animal models was conducted in Isfahan University of Medical Sciences. Methods Mesenchymal stem cells (MSCs) were obtained from subcutaneous adipose tissue of 4 dogs. Undifferentiated cells were incubated with a hydroxyapatite/beta-tricalcium phosphate scaffold in an osteogenic medium for 21 days. read more A maxillary defect simulating human alveolar cleft was created from the alveolar crest to nasal floor with 15 mm width bilaterally. Two months later, the defect was filled with autogenous bone graft harvested from tibia on one side and tissue-engineered graft from MSCs on the other side. Digital radiography was performed on days 15, 30, 45, 60, 75, and 90 after grafting. Radiographic density was calculated by the mean numeric value of pixels of the desired area ranging from 0 (darkest) to 255 (lightest) by associated software. Statistical Analysis Used The data were analyzed by Statistical Package for the Social Sciences using descriptive statistics and two-way repeated-measure analysis of variance test (α = 0.05). Results Mean density measured for autogenous bone graft group was 110.72, 82.70, 75.76, 93.57, 100.22, and 100.32 in days 15, 30, 45, 60, 75, 90, respectively and 120.7, 87.62, 83.72, 92.02, 92.30, and 93.77 in stem cell group. Although the time lapse was a significant factor in two groups (P = 0.01), the results indicated that the difference between two groups was not statistically significant (P = 0.942). Conclusion Tissue-engineering can be used as an alternative method in reconstruction of bony defects with predictable clinical outcomes.Introduction Mandible undergoes age- and sex-related structural changes similar to other bones of the body. Thus, morphometric analysis of the mandible helps in age and sex determination. Aim To investigate the influence of age and sex on the mandible by measuring three parameters, i.e. gonial angle, ramus height and bigonial width. Materials and Methods A retrospective radiomorphometric analysis was conducted in the department of Oral Medicine and Radiology. A total of 300 panoramic radiographs (150 males and 150 females) equally distributed in six study groups according to the age were analysed. The measurements were performed using DIGORA 2.8 software for Windows. The acquired data was statistically analysed by one way ANOVA test and Student's t-test using SPSS (v. 19.0). Results Statistically significant differences according to age were found in gonial angle dimensions. Ramus height and bigonial width did not demonstrate statistically significant co-relation with age. According to sex, all the three study parameters showed statistically highly significant differences. Conclusion The morphometric analysis of the mandible is a useful tool for age estimation and sex determination.Aim The aim of this study was to evaluate demographic and clinical factors involved in the immediate seeking of care after traumatic dental injury (TDI) in Brazilian children. Materials and Methods Records from 74 patients, age ranged 1-11 years, who sought treatment at the School of Dentistry of Ribeirão Preto at University of São Paulo, Brazil, were collected. Data was analyzed using the Epi Info 7.0 software by t-test, odds ratio calculation, Chi-square, or Fisher's exact tests. Results Twenty-three (31.1%) sought dental treatment immediately and 51 (68.9%) did not seek dental treatment immediately. The most common type of trauma was lateral luxation (44.6%). In primary teeth, 31 cases (60.78%) involved the soft tissue and 16 (39.2%) involved hard tissue injuries. While in permanent teeth, 20 cases (40%) involved soft tissue and 24 (60%) involved hard tissue injuries had more traumas in the hard tissue (P = 0.04). The type of injury and dentition was not associated with the time that the guardians sought dental treatment (P > 0.05). None of the factors were involved in immediately seeking care after TDI. Conclusion Moreover, the majority of parents/caregivers did not immediately seek dental treatment after TDI, regardless of the type of injury.Background The position of the mental foramen (MF) is particularly relevant in dentistry. The incorporation of new imaging techniques, such as cone-beam-computed tomography (CBCT), can be used to identify anatomic dimorphic traits. Aims This study evaluated the sexual dimorphism of MF position by CBCT among a selected population. Methods Fifty CBCT images from 20 to 40-year-old subjects (25 men and 25 women) were evaluated. The horizontal position was evaluated using the al Jasser-Nwoku classification to identify the position of the MF in the mandible. Two measurements were obtained on coronal sections to evaluate the vertical position of the MF the distance from the uppermost alveolar ridge to the upper edge of the foramen and the distance from the inferior edge of the foramen to the lower border of the mandible. Statistical Analysis Used Comparisons between sexes and sides were performed with Student's t-test and Chi-square tests. Results The most frequent location of the MF was in line and below of the second premolar tooth in both men and women (P > 0.05). Additionally, significant differences were found between sexes for the distance from the inferior edge of the foramen to the lower border of the mandible in each side (P less then 0.001 for the right and left sides). Conclusions Horizontal position of the MF is not a sexually dimorphic feature and it is predominantly in line and below the second premolar tooth. Women present the MF in a more caudal position, closer to the mandibular base when compared to men.Objectives This study was aimed at determining the specific signs of close relationship between impacted mandibular third molar (IMTM) root and inferior alveolar nerve (IAN) canal as visualised on digital panoramic radiograph or orthopantomograph (OPG) which should indicate as well as contraindicate the need for cone beam computed tomography (CBCT) imaging based on hierarchical model of Fryback and Thornbury. Materials and Methods The sample consisted of 120 individuals (200 IMTM) who had undergone OPG as well as CBCT imaging as preoperative radiographic evaluation before surgical extraction. On panoramic radiographs; Rood and Sheehab's radiographic signs of IMTM root and IAN canal, impacted third molar position based on Winter's classification and depth of impaction based on Pell and Gregory's classification were evaluated. On CBCT; presence/absence of corticalization and the status of the buccal and lingual cortices (thinning/perforation) were evaluated. These findings of OPG were compared to CBCT findings to determine the better modality based on hierarchical model of Fryback and Thornbury.