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Three key components were identified that underlie engagement with data and HIT systems data audience identification, defined data purpose and structures for participation in both data design and maintenance.
Within the context of primary care, these findings have implications for effective integration of HIT systems into primary care delivery.
Within the context of primary care, these findings have implications for effective integration of HIT systems into primary care delivery.In March 2020, the World Health Organization declared the COVID-19 outbreak a pandemic, which generated concerns that the NHS could be overwhelmed. The predicted increase in the number of patients requiring hospitalisation prompted the need to increase the number of clinical staff working on hospital wards, particularly healthcare support workers (HCSWs), who play a crucial role in addressing the care needs of older people. This article describes how one health board in Scotland trained and redeployed volunteers among its staff to work as temporary HCSWs in its main hospital during the pandemic. A fast-track, one-day training course was delivered in March and April 2020 to 104 staff from various backgrounds - some non-clinical - by a team of volunteer trainers. Staffing during an emergency, such as the COVID-19 pandemic, presents significant challenges, but the experience at NHS Borders shows that it is possible to develop a training course rapidly and provide additional band 2 staff to supplement the support workforce in a time of crisis.Male infertility in animals are caused by many factors and mostly by genetic mutations. Spontaneously mutated mice have long been used as important animal models for basic medical researches on human genetic diseases and as valuable research tools for discovering new genes and their functions. Spontaneously mutated mice are often detected as random genetic events in zoos or research institutions that house large groups of mice, and they carry various phenotypes, some of which can cause male sterility. This review summarizes the types of spontaneously mutated mice carrying male infertility-related phenotypes to provide an animal model for the study of male infertility.Male sexual dysfunction involves sexual desire disorder, penile erection disorder, insertion disorder, and ejaculation disorder according to the process of sexual activity, among which, erection disorder, premature ejaculation, hypoactive sexual desire and other related diseases are very common. Oxytocin is a neuroendocrine hormone and benefits childbirth and breastfeeding. Recent studies show that oxytocin can induce penile erection in multiple brain regions, nasal administration of oxytocin can increase sexual desire, and there is a certain correlation between oxytocin and premature ejaculation, all indicating the potential value of the studies on the correlation of oxytocin and male sexual function. This review focuses on the role of oxytocin in male erection, ejaculation/premature ejaculation and sexual desire, as well as the specific brain regions involved and the action mechanisms of oxytocin.
To investigate the improving effect of Duzhong Butiansu Capsules (DBC) on the fertility of male mice.
Forty-eight 4-week-old SPF male Kunming mice weighing 12-16 g were randomly divided into four groups of equal number, distilled water (DW) control, Shengjing Capsules (SJC), low-dose DBC and high-dose DBC, treated intragastrically with distilled water, SJC at 0.8 g/kg/d, DBC at 0.694 g/kg/d and DBC at 1.388 g/kg/d, respectively, all for 3 weeks. After 2 weeks of treatment, the male mice were mated with female ones at a 2∶1 ratio for 1 week. Then, all the male animals were sacrificed for observation of the morphological changes in the testis and epididymis by HE staining, detection of the sperm count and motility, coefficients of different organs and expression of the androgen receptor (AR) in the testis, measurement of the levels of E2, LH, FSH and T by ELISA, and determination of the concentrations of aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatinine (Cr) and urea nitrogen (BUN but there were no statistically significant differences between the DW control and the low- or high-dose DBC groups in the levels of serum T, FSH, LH, E2, Cr and BUN (P > 0.05).
Duzhong Butiansu Capsules could improve the fertility of male mice, which has provided some experimental evidence for the clinical application of the medicine.
Duzhong Butiansu Capsules could improve the fertility of male mice, which has provided some experimental evidence for the clinical application of the medicine.
To evaluate the effect and safety of the magnetic resonance electromagnetic therapy (MREM) combined with Qianlie Beixi Capsules (QBC) in the treatment of chronic prostatitis / chronic pelvic pain syndrome (CP/CPPS).
Using a prospective, two-center, randomized, open, positive drug-loading, parallel-controlled clinical design, we randomly divided 124 patients with CP/CPPS into a control and an observation group of equal number, the former treated with QBC and the latter with QBC combined with MREM for a course of 14 days. Then, we compared the NIH-CPSI scores before and after treatment, the total effectiveness rate and safety between the two groups of patients.
After treatment, the patients in both the observation and control groups showed significantly improved total and specific item scores on NIH-CPSI (P < 0.05), and those of the observation group achieved even more significant improvement than the controls either in the total NIH-CPSI score (16.65 ± 7.90 vs 21.95 ± 5.70, P < 0.05) or in the pain symptom score (7.34 ± 3.26 vs 9.50 ± 2.47, P < 0.05), urination symptom score (3.53 ± 2.56 vs 4.50 ± 2.35, P < 0.05) and quality of life score (5.94 ± 2.89 vs 8.03 ± 2.60, P < 0.05). The total effectiveness rate was remarkably higher in the observation than in the control group (83.87% vs 53.23%, P < 0.05). selleck products No adverse events or reactions were observed in either group of the patients during the trial.
Magnetic resonance electromagnetic therapy combined with Qianlie Beixi Capsules can significantly relieve the clinical symptoms of CP/CPPS patients with high effectiveness and safety.
Magnetic resonance electromagnetic therapy combined with Qianlie Beixi Capsules can significantly relieve the clinical symptoms of CP/CPPS patients with high effectiveness and safety.