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This cross-sectional study investigated the association of physical and social anhedonia with suicidality in patients with major depressive disorder (MDD), schizophrenia, and in non-psychiatric controls.

All participants completed the revised Physical Anhedonia Scale (RPAS) and the revised Social Anhedonia Scale (RSAS) and were subdivided according to positive life-time suicide attempt history. MDD patients were evaluated with the Montgomery-Ãsberg Depression Rating Scale (MADRS), healthy respondents with the Patient Health Questionnaire-9 (PHQ-9), and schizophrenia patients with the Calgary Depression Scale for Schizophrenia (CDSS).

In 683 study participants, the prevalence of each anhedonia was the highest in MDD, followed by schizophrenia, and lowest in the control group. Among MDD patients, those with physical and social anhedonia had greater rates of recent suicidal ideation, while a higher frequency of individuals with life-time suicide attempts was detected in those with only social anhedonia. In contrast, no association between either anhedonia and life-time suicide attempts or recent suicidal ideation was found in patients with schizophrenia.

Assessing social and physical anhedonia might be important in MDD patients, given its association with both life-time suicide attempts and recent suicidal ideation. Suicidality in schizophrenia, while unrelated to anhedonia, might include other risk factors.

Assessing social and physical anhedonia might be important in MDD patients, given its association with both life-time suicide attempts and recent suicidal ideation. Suicidality in schizophrenia, while unrelated to anhedonia, might include other risk factors.

The working conditions of professional fashion models may place them at risk for negative outcomes including disordered eating. New policies in the United States and France, including providing private changing areas and requiring medical certificates, have been implemented to protect models from pressures to be extremely thin and sexual harassment. This study evaluated the implementation of the new policies during the week of New York Fashion Week, February 2018 (NYFW Fall'18).

A sample of 76 fashion models (87% female) aged over 18 years who had participated in NYFW Fall'18 completed an online survey, reporting on behaviors and experiences occurring during NYFW Fall'18.

A large proportion of respondents reported unhealthy weight control behaviors, including skipping meals (54%), intravenous drips (39%), and self-induced vomiting (25%). Fewer than half reported being always or sometimes provided with a private changing area, with 45% reporting experiencing lack of privacy when changing. A subset (n = 15) had obtained a health certificate for events in Paris. Most health providers had assessed weight, but few assessed eating and exercise behaviors.

Policy interventions to improve health and safety of models are not yet achieving intended goals and require continued monitoring.

Policy interventions to improve health and safety of models are not yet achieving intended goals and require continued monitoring.

To estimate the incidence of the need for a dental prosthesis during early adulthood and its association with socioeconomic and oral disorder trajectories.

In 1982, in the city of Pelotas, all live births (n=5914) and their mothers were assessed. A representative sample of this cohort study was examined for oral health conditions at 15, 24 and 31years (Oral Health Study-OHS). The need for a dental prosthesis was assessed at 24 and 31years of age, and variables of interest (gender, skin colour, socioeconomic status (SES), use of dental services, caries and periodontal disease) were collected from different waves of this cohort. SGC 0946 Longitudinal association between outcome and variables of interest was assessed using multilevel mixed models.

A total of 539 individuals were assessed in 2013 (60.7% response rate). The need for a dental prosthesis was 28.9% at 24years. (95% CI 24.9-33.2) and 49.0% at 31years (95% CI 44.7-53.3). Risk of presenting with a need for a dental prosthesis was higher in users of public services. Downwardly mobile and lower SES trajectory groups presented a higher risk of the need for a dental prosthesis. High-risk caries trajectory group showed a higher risk of presenting with the need for a dental prosthesis from 24 to 31years.

Our findings demonstrate that the need for dental prosthesis from 24 to 31years old was determined by trajectories of exposure during the life cycle, reinforcing that tackling socioeconomic inequalities at any stage of life can have an effect on an individual's oral health.

Our findings demonstrate that the need for dental prosthesis from 24 to 31 years old was determined by trajectories of exposure during the life cycle, reinforcing that tackling socioeconomic inequalities at any stage of life can have an effect on an individual's oral health.

To quantify the error detection power of a new treatment delivery error detection method. The method validates monitor unit (MU) resolved beam apertures using real-time EPID images.

The on-board EPID imager was used to measure cine-EPID (~10Hz) images for 27 beams from 15 VMAT/SBRT clinical treatment plans and five nonclinical plans. For each frame acquisition, planned apertures were interpolated from the treatment plan multileaf collimator (MLC) positions expected during the frame acquisition interval. Inaccurate deliveries were identified by monitoring in-aperture missed fluence and out-of-aperture excess fluence beyond a specified buffer. Delivery errors were simulated by perturbing the planned MLC positions before comparison with nonperturbed measured apertures. Systematic 1-5mm MLC leaf shifts were used to train a logistic regression model to determine the error detection threshold. Model accuracy was monitored using tenfold cross-validation. The model's error detection ability was tested with other rror detection, at 1% of a beam's delivery, make the aperture check a potential candidate for QA of on-line adaptive radiotherapy, or other situations in which pretreatment delivery QA is impractical.

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