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ite cyclists of various disciplines, which opens opportunities for application in talent orientation and transfer.

Exercise intolerance, evaluated by O2 consumption, predicts mortality in cystic fibrosis (CF). People with CF exhibit skeletal muscle dysfunctions that may contribute to an imbalance between O2 delivery and utilization. Sildenafil, a phosphodiesterase type 5 inhibitor, increases blood flow and improves O2 consumption, although the exact mechanisms in CF have yet to be elucidated. Thus, we hypothesized that exercise intolerance in CF is limited primarily by an impaired skeletal muscle O2 utilization, and sildenafil improves exercise tolerance in CF by addressing this mismatch between O2 demand and extraction.

Fifteen individuals with mild to moderate CF and 18 healthy controls completed an incremental exercise test and measurements of gaseous exchange, chronotropic response, hemodynamics, and O2 extraction and utilization. People with CF also completed a 4-wk treatment with sildenafil with a subsequent follow-up evaluation after treatment.

Skeletal muscle O2 extraction and utilization during exercise werk of sildenafil treatment improves the capacity of the skeletal muscle to use O2 more efficiently during exercise. Findings from the present study highlight the importance of targeting skeletal muscle O2 utilization to improve exercise tolerance in CF.

This study examined one-year reliability and construct validity of survey items relating to time spent on muscle-strengthening exercise (MSE) in a subset of a large prospective cohort.

Participants (N = 293 men, 433 women; age 32-73 years) were selected from the Cancer Prevention Study-3. Information was collected using a one-year pre- and post-survey and four 7-day diaries throughout the year. The pre- and post-surveys collected time spent on MSE in two ways one question captured MSE activities performed during a typical 24-hour period (24-hour survey), and another question captured leisure-time physical activities performed in hours/week and months/year (LTPA survey). Time spent on MSE using the LTPA survey was calculated for individual MSE items and summed for total MSE time. One-year reliability was assessed by comparing the responses between the pre-survey and post-survey using Spearman's correlation coefficients. Construct validity was assessed by computing Spearman's correlation coefficients betweety estimates are acceptable across all sociodemographic subgroups.Behm, DG, Alizadeh, S, Hadjizadeh Anvar, S, Mahmoud, MMI, Ramsay, E, Hanlon, C, and Cheatham, S. Foam rolling prescription a clinical commentary. J Strength Cond Res 34(11) 3301-3308, 2020-Although the foam rolling and roller massage literature generally reports acute increases in range of motion (ROM) with either trivial or small performance improvements, there is little information regarding appropriate rolling prescription. The objective of this literature review was to appraise the evidence and provide the best prescriptive recommendations for rolling to improve ROM and performance. The recommendations represent studies with the greatest magnitude effect size increases in ROM and performance. A systematic search of the rolling-related literature found in PubMed, ScienceDirect, Web of Science, and Google Scholar was conducted using related terms such as foam rolling, roller massage, ROM, flexibility, performance, and others. From the measures within articles that monitored ROM (25), strength (41), jump (41), fatigue (67), and sprint (62) variables; regression correlations and predictive quadratic equations were formulated for number of rolling sets, repetition frequency, set duration, and rolling intensity. The analysis revealed the following conclusions. To achieve the greatest ROM, the regression equations predicted rolling prescriptions involving 1-3 sets of 2-4-second repetition duration (time for a single roll in one direction over the length of a body part) with a total rolling duration of 30-120-second per set. selleck compound Based on the fewer performance measures, there were generally trivial to small magnitude decreases in strength and jump measures. In addition, there was insufficient evidence to generalize on the effects of rolling on fatigue and sprint measures. In summary, relatively small volumes of rolling can improve ROM with generally trivial to small effects on strength and jump performance.Egan-Shuttler, JD, Edmonds, R, and Ives, SJ. The efficacy of heart rate variability in tracking travel and training stress in youth female rowers A preliminary study. J Strength Cond Res 34(11) 3293-3300, 2020-Heart rate variability (HRV) is a reliable indicator of cardiac parasympathetic activity and has been used in athletic populations to measure training adaptations. To date, there is limited research showing whether HRV is practical in youth female athletes and rowers during short periods of overload training. The purpose of this study was to evaluate the practicality of HRV in documenting training responses during a period of overload training in youth female rowers. Time-domain (SD of N-N intervals, SDNN; root mean square of successive differences, RMSSD) and nonlinear (SD1) indices of HRV were recorded during baseline training, daily during the 6-day training camp, and 1 week after the camp in 5 athletes from an elite, high-school, rowing team. Training duration and rate of perceived exertion were recorded to document training load. Training load during the camp was 76% above the athlete's normal workload (2,258 ± 459 vs. 1,280 ± 356 arbitrary units (a.u.)). Using progressive statistics, cardiac vagal activity (RMSSD and SD1) was very likely reduced during each day of the camp when compared with baseline training, although returned to baseline within a week of the training camp. Interestingly, SDNN was reduced throughout the training camp and remained reduced up to a week after the training camp (78% likely; effect size = -0.32). These insights add value to HRV's use in youth sport and provides coaches with an easy, cost-effective means to monitor the physiological response to training, allowing fine-tuning of training, potentially enhancing performance.