Aggerliu9344

5, Fig. 3, Ref. 34).

IPI was a potential candidate for evaluating the respiratory status, and a limiting tool to prevent unnecessary diagnostic tests and save time in determining the treatment course in dyspneic patients at ED (Tab. 5, Fig. 3, Ref. 34).The effect of poly(lactic‑co‑glycolic acid) (PLGA) on structure, degradation, drug release and mechanical properties of fibrin/pomegranate(F/POM)-based drug‑eluting scaffolds have been studied comprehensively.

Nanoparticle-fibrin is prepared from thrombin and fibrinogen dissolved in NaOH and HCl. Then pomegranate powder is added to it. Nanoparticles/pom are provided by freeze drying and freeze milling. The 3-D scaffold of poly(lactide-co‑glycolic acid) (PLGA) was prepared via salt‑leaching solvent/casting leaching method and impregnated with nanofibrin-pom. Structural and chemical component of the scaffolds were evaluated by transmission and scanning electron microscopy and furrier transmission infrared spectroscopy, respectively. Moreover, the scaffolds were characterized from the degradation rate and drug releasing rate points of view of human Adipose Derive Stem Cells (hADSCs). Cytotoxicity effects of the scaffold were evaluated on hADSCs via MTT assay.

The results showed that the size of nanoparticles 7, Ref. 53) Keywords hybrid composites, drug delivery, carrier, nanoparticles, scaffold.

The aim of this study was to investigate the association of RDW with all-cause mortality and disease progression in patients with CKD in stage 3-4.

This longitudinal observational cohort study of patients with CKD was conducted at a single center. We categorized baseline RDW into two groups by its median (14.9 %). The associations between baseline RDW values and all-cause mortality over 56 months were examined in unadjusted and adjusted models. The effect of RDW value on renal outcomes and mortality was evaluated by using Cox regression analysis.

A total of 261 patients were enrolled in the study. During an average follow-up of 56 months, 19.8 % of patients died. The area under the ROC curve for RDW for all-cause mortality was 0.746, with sensitivity of 0.74 and specificity of 0.69 for a cut-off point of 14.3 %. The incidence of all-cause mortality in the group with increased RDW was significantly higher than in the normal RDW group (p < 0.001). Actinomycin D The Cox proportional hazard model showed that the elevated RDW level was an independent risk factor for all-cause mortality in patients with CKD in stage 3-4.

RDW is a powerful and independent prognostic marker for predicting all-cause mortality and disease progression in stage 3-4 of CKD (Tab. 4, Fig. 4, Ref. 29).

RDW is a powerful and independent prognostic marker for predicting all-cause mortality and disease progression in stage 3-4 of CKD (Tab. 4, Fig. 4, Ref. 29).

To analyse the effect of systemic inflammatory status in patients with primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) by calculating platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR).

This retrospective case-control study included 200 patients with POAG, 22 patients with PACG and 100 healthy subjects. The participants' white-blood-cell, lymphocyte, neutrophil, and platelet counts were recorded from previous blood assays. NLR and PLR were calculated manually. Results were compared among the groups.

Both the POAG and PACG groups had higher platelet counts and PLR values than the control group (p=0.001 and p=0.001; respectively). The difference in NLR between POAG, PACG and control groups was not statistically significant (p=0.076). The POAG group had higher NLR values than the control (p=0.035).

Both the POAG and the PACG groups exhibited higher platelet and PLR levels than the control. These results indicate a potential role of systemic inflammation in the pathogenesis of POAG and PACG (Tab. 4, Fig. 1, Ref. 35).

Both the POAG and the PACG groups exhibited higher platelet and PLR levels than the control. These results indicate a potential role of systemic inflammation in the pathogenesis of POAG and PACG (Tab. 4, Fig. 1, Ref. 35).

Our study aimed to investigate neurological symptoms in patients with COVID-19 and contribute to this area of limited knowledge.

Increasing evidence shows that neurotropism is a common feature of Coronaviruses (CoVs). Like the other CoVs, SARS-CoV 2 uses angiotensin-converting enzyme 2 (ACE2). The brain is thought to express ACE2 receptors detected on glial cells and neurons. There are also ACE2 receptors in skeletal muscles. Our study aimed to investigate neurological symptoms in patients with COVID-19 and contribute to this area of limited knowledge.

A total of 51 patients, presented to hospitalized in our hospital between March 23, 2020 and April 16, 2020 were included in the study. The diagnosis of all patients included in the study was made according to the WHO interim guideline. The patients were divided into two subgroups as mild and severe course according to the severity of the disease.

Neurological symptoms were detected in 16 (31.37 %) patients. Muscle injury was detected in 10 (19.61 %) paropism, muscle injury, headache.

This study was aimed to investigate the risk factors for mortality in patients with COVID-19.

For this retrospective cohort study, we included 121 deceased and 436 discharged cases with COVID-19 in Babol, Northern Iran. The cases were between March 1 to April 1, 2020.

Multivariate Poisson regression analysis revealed that older age (aRR 1.03, 95% CI 1.01, 1.05, p < 0.001), hospital length of stay (aRR 0.94, 95% CI 0.90, 0.97, p = 0.003), ICU admission (aRR 4.34, 95% CI 2.95, 6.37, p < 0.001), cerebrovascular disease (aRR 1.96, 95% CI 1.20, 3.19, p = 0.007), ventilator-associated pneumonia (VAP) (aRR 2.09, 95% CI 1.22, 3.55, p = 0.006), septic shock (aRR 2.98, 95% CI 1.44, 6.19, p = 0.003), acute respiratory distress syndrome (ARDS) (aRR 3.80, 95% CI 2.28, 6.31, p < 0.001), acute kidney failure(AKF) (aRR 1.45, 95% CI 1.12, 3.76, p = 0.021), acute heart failure (AHF) (aRR 1.63, 95% CI 1.01, 2.62, p = 0.043) and lymphocyte count (aRR 3.01, 95% CI 1.99, 4.57, p < 0.001) were associated with mortality.