Adamsenbrantley0284

This study investigates the effects of build orientation and laser-energy density on the pore structure, microstructure, and tensile properties of Inconel 718 manufactured by laser powder bed fusion. Three different build conditions were selected for comparison based on previous research (namely, the conditions that resulted in the worst and best fatigue lifetimes) 0° build orientation and 38 J/mm3 laser-energy density, 0° build orientation and 62 J/mm3 laser-energy density, and 60° build orientation and 62 J/mm3 laser-energy density. Differences in porosity were measured between each build condition. In terms of microstructure, all three conditions exhibited a predominantly texture in the build direction, grains elongated in the build direction, and a sub-grain structure oriented with the build direction that consisted of dislocation networks decorated with nano-scale precipitates. Build orientation (0° versus 60° with respect to the build plate) produced a difference in yield strength due to anisotropic grain morphology and effective grain size. The low laser-energy density specimens showed a significant decrease in all mechanical properties compared to the high laser-energy density specimens because the amount (6.91% by volume) and size of the lack-of-fusion porosity (from insufficient melting) sur-passed a level at which microstructure (the grain and sub-grain structure) no longer governs quasi-static mechanical properties. This work provides insight that could enable the tunability of structure-property relationships in as-built Inconel 718 by optimizing laser-energy density and build orientation.This work presents a novel process design optimization framework for additive manufacturing (AM) by integrating physics-informed computational simulation models with experimental observations. The proposed framework is implemented to optimize the process parameters such as extrusion temperature, extrusion velocity, and layer thickness in the fused filament fabrication (FFF) AM process, in order to reduce the variability in the geometry of the manufactured part. A coupled thermo-mechanical model is first developed to simulate the FFF process. The temperature history obtained from the heat transfer analysis is then used as input for the mechanical deformation analysis to predict the dimensional inaccuracy of the additively manufactured part. The simulation model is then corrected based on experimental observations through Bayesian calibration of the model discrepancy to make it more accurately represent the actual manufacturing process. Vardenafil Based on the corrected prediction model, a robustness-based design optimization problem is formulated to optimize the process parameters, while accounting for multiple sources of uncertainty in the manufacturing process, process models, and measurements. Physical experiments are conducted to verify the effectiveness of the proposed optimization framework.In around the world, mosquito control is considered a most important because of the incapable of synthetic insecticides and the ecological pollution about by them. In this manner, need the eco-friendly insecticides to efficient control the mosquito disease is the need of the hour. We synthesized the eco-friendly of zinc oxide nanoparticles (ZnO-NPs) using the Knoxia sumatrensis aqueous leaf extract (Ks-ALE) as a reducing and stabilizing agent. The synthesis of ZnO-NPs was confirmed by UV with an absorption peak at 354 nm. ZnO-NPs crystal structure was analyzed by X-ray diffraction (XRD). Fourier transform infrared spectroscopy (FT-IR) spectra revealed the chloride, cyclic alcohols, sulfonamies, carboxylic acids, oximes, phosphines, alkenes and alcohol & phenol. Field emission-scanning electron microscopy (FE-SEM) showed that the NP's are rod shaped with 50-80 nm size and also energy dispersive spectra (EDaX) spectra showed presence of zinc. Antioxidant assay showed superior activity and evidenced by DPPH, ABTS and H2O2 radical assays. Furthermore, the ZnO-NPs exhibited strong activity in MCF-7 cell line with IC50 value is 58.87 μg/mL. Mosquito larvicidal activity of ZnO-NPs produced significant activity and excellent larvicidal activity was noticed in Cx. quinquefasciatus with LC50 0.08, mg/mL and LC9019.46 mg/mL. This study suggests that synthesized ZnO-NPs using Knoxia sumatrensis leaf extract have good biological activities and it makes them an ideal candidate for pharmacological studies.[This corrects the article DOI 10.1016/j.toxrep.2018.02.003.][This corrects the article DOI 10.1016/j.toxrep.2018.03.007.][This corrects the article DOI 10.1016/j.toxrep.2018.03.004.][This corrects the article DOI 10.1016/j.toxrep.2017.12.015.][This corrects the article DOI 10.1016/j.toxrep.2018.02.006.][This corrects the article DOI 10.1016/j.toxrep.2018.01.003.][This corrects the article DOI 10.1016/j.toxrep.2018.03.012.][This corrects the article DOI 10.1016/j.toxrep.2018.02.019.][This corrects the article DOI 10.1016/j.toxrep.2018.01.006.][This corrects the article DOI 10.1016/j.toxrep.2017.12.019.][This corrects the article DOI 10.1016/j.toxrep.2017.12.011.][This corrects the article DOI 10.1016/j.toxrep.2018.01.001.][This corrects the article DOI 10.1016/j.toxrep.2018.02.001.][This corrects the article DOI 10.1016/j.toxrep.2018.02.004.].[This corrects the article DOI 10.1016/j.toxrep.2018.08.014.][This corrects the article DOI 10.1016/j.toxrep.2019.11.018.][This corrects the article DOI 10.1016/j.toxrep.2018.06.007.][This corrects the article DOI 10.1016/j.toxrep.2019.06.019.][This corrects the article DOI 10.1016/j.toxrep.2018.08.023.][This corrects the article DOI 10.1016/j.toxrep.2019.06.012.][This corrects the article DOI 10.1016/j.toxrep.2019.06.011.][This corrects the article DOI 10.1016/j.toxrep.2018.10.003.][This corrects the article DOI 10.1016/j.toxrep.2019.07.001.][This corrects the article DOI 10.1016/j.toxrep.2018.08.017.][This corrects the article DOI 10.1016/j.toxrep.2019.06.003.][This corrects the article DOI 10.1016/j.toxrep.2018.03.010.][This corrects the article DOI 10.1016/j.toxrep.2019.01.004.][This corrects the article DOI 10.1016/j.toxrep.2019.06.009.][This corrects the article DOI 10.1016/j.toxrep.2019.04.001.].