Aagesenwaller0358

administration is not yet possible. Thus, more studies in this area, aiming for the development of an insulin delivery system that can promote more adherence to the treatment and patient comfort, are required.Super-hydrophilicity is a desired but rarely reported surface finish of polymer materials, so the methods for achieving such a property represent a great scientific and technological challenge. The methods reported by various authors are reviewed and discussed in this paper. The super-hydrophilic surface finish has been reported for polymers functionalized with oxygen-rich surface functional groups and of rich morphology on the sub-micrometer scale. The oxygen concentration as probed by X-ray photoelectron spectroscopy should be above 30 atomic % and the roughness as determined by atomic force microscopy over a few nm, although most authors reported the roughness was close to 100 nm. A simple one-step oxygen plasma treatment assures for super-hydrophilicity of few polymers only, but the technology enables such a surface finish of almost any fluorine-free polymer providing a capacitively coupled oxygen plasma that enables deposition of minute quantities of inorganic material is applied. More complex methods include deposition of at least one coating, followed by surface activation with oxygen plasma. Fluorinated polymers require treatment with plasma rich in hydrogen to achieve the super-hydrophilic surface finish. The stability upon aging depends largely on the technique used for super-hydrophilization.An eco-friendly and novel water treatment material was synthesized using sodium lignosulfonate modified polystyrene (SLPS), which can be used to eliminate phenols in aqueous solution. SLPS was characterized by BET, FTIR, SEM, and EDS. The effect of the initial pH value, phenol content, adsorption time, and temperature on the absorbability of phenol in SLPS was investigated through adsorption experiments. It was found that SLPS could efficiently adsorb phenol in aqueous solution at a pH value of about 7. The test results revealed that the kinetic adsorption and isotherm adsorption could be successfully described using the pseudo second-order and Langmuir models, respectively. selleck kinase inhibitor It was illustrated that the phenol adsorption on SLPS was dominated by chemisorption and belonged to monolayer adsorption. The max. phenol adsorption value of SLPS was 31.08 mg/g at 30 °C. Therefore, SLPS displayed a great potential for eliminating phenol from polluted water as a kind of novel and effective adsorbent.Pistacia lentiscus L. is a Mediterranean shrub known for its health promoting effects attributed to a large extent to polyphenols accumulated in all parts of the plant. Microwave-assisted extraction is a green extraction technique enabling fast and effective isolation of plant polyphenols. Therefore, the aim of this research was to optimize the microwave-assisted extraction of polyphenols from Pistacia lentiscus L. leaves and fruit in terms of temperature, extraction time and microwave power and to evaluate their polyphenolic profile by UPLC/ESI-MS2 and antioxidant capacity by ORAC assay. Optimal extraction conditions for leaf polyphenols were 69 °C, 512 W and 12 min, while for fruit were slightly more intensive-75 °C, 602 W and 15 min. Obtained total phenolic content in leaves and fruit was similar to that obtained after 30 min of the heat-reflux method. The polyphenolic profile of extracts included 34 compounds, with myricetin glycosides being the most abundant compounds among flavonoids in Pistacia lentiscus L. leaves and fruit and gallic acid and its derivates among the phenolic acids. ORAC assay showed higher antioxidant capacity for Pistacia lentiscus L. leaves extract than for fruit, which is in correlation with their respective phenolic content.Lower body negative pressure (LBNP) application simulates hemorrhage. We investigated how seasons affect coagulation values at rest and during LBNP. Healthy participants were tested in cold (November-April) and warm (May-October) months. Following a 30-min supine period, LBNP was started at -10 mmHg and increased by -10 mmHg every five minutes until a maximum of -40 mmHg. Recovery was for 10 min. Blood was collected at baseline, end of LBNP, and end of recovery. Hemostatic profiling included standard coagulation tests, calibrated automated thrombogram, thrombelastometry, impedance aggregometry, and thrombin formation markers. Seven men (25.0 ± 3.6 years, 79.7 ± 7.8 kg weight, 182.4 ± 3.3 cm height, and 23.8 ± 2.3 kg/m2 BMI) and six women (25.0 ± 2.4 years, 61.0 ± 8.4 kg weight, 167 ± 4.7 cm height, and 21.8 ± 2.4 kg/m2 BMI) participated. Baseline levels of prothrombin (FII), tissue factor (TF) and markers for thrombin generation F1+2 and the thrombin/antithrombin complex (TAT) were higher during summer. Factor VIII, prothrombin fragment 1+2 (F1+2), TAT and the coagulation time showed significant increases during LBNP in both seasons. Some calibrated automated thrombography variables (Calibrated automated thrombography (CAT) lag, time to peak (ttPeak), peak) shifted in a procoagulant direction during LBNP in summer. Red blood cell counts (RBC), hemoglobin and white blood cell counts (WBC) decreased during LBNP. LBNP application reduced prothrombin time in winter and activated partial thromboplastin time in summer. Greater levels of FII, TF, F1+2, and TAT-a more pronounced LBNP-induced procoagulative effect, especially in CAT parameters (lag time (LT), Peak, ttPeak, Velindex)-were seen in summer. These results could have substantial medical implications.Although it is well-established that exoskeletons as robots attached to the extremities of the human body increase their strength, limited studies presented a computer and mathematical model of a human leg hydraulic exoskeleton based on anthropometric data. This study aimed to examine lower limb joint angles during walking and running by using Inertial Measurement Units. The geometry and kinematic parameters were calculated. Twenty-six healthy adults participated in walking and running experiments. The geometric model of a human leg hydraulic exoskeleton was presented. Joint angle data acquired during experiments were used in the mathematical model. The position and velocity of exoskeleton actuators in each phase of movement were calculated using the MATLAB package (Matlab_R2017b, The MathWorks Company, Novi, MI, USA). The highest velocity of the knee actuator during walking and running was in the swing phase, 0.3 and 0.4 m/s, respectively. For the ankle and hip joints, the highest velocity of actuators occurred during the push-off phase.