Buckmorales6146

A global approach towards quality management highlights the need for constructing a new body of knowledge that views the field of global quality from a systems perspective. The current article presents the results of an ongoing research based on quantitative and qualitative studies. The qualitative study used Grounded Theory as its theoretical and methodological framework. The subjects of this study were experts in systems thinking, including project managers and engineers who were interviewed in depth about their work in global organisations in a business environment characterized by complex and dynamic challenges. In addition, several qualitative and quantitative tools were applied in a field study of 18 multinational companies. In view of the requirement for developing new global quality management terminology, this article presents several new key concepts in this field, which have resulted from the ongoing research, with emphasis on a systems-oriented rationale and perspective. As such, the article is an important stage in building this new body of knowledge, and towards the conceptualization of key variables used in global quality management, from a systems approach that interacts with the fields of international management and strategic management.This study investigates the effect of varying test conditions including ambient temperature (19, 22, and 25 °C), mass charges of R600a refrigerant (40, 50, 60, and 70 g), and concentrations of TiO2 nanolubricant (0, 0.2 and 0.4 g/L) on the performance of a slightly modified 100g R134a domestic refrigeration system. The investigated parameters include evaporator air temperature, energy consumption, coefficient of performance, and second law efficiency of the system. The results showed that the performance of the refrigeration system at 0.2 and 0.4 g/L concentrations of TiO2 nanolubricant, improved at optimum ambient temperature and R600a mass charge conditions. At optimum conditions, the evaporator air temperature and energy consumption reduced within the range 5.26 to 26.32 %, and 0.13 to 14.09 % respectively, while the coefficient of performance and second law efficiency increased within the range 0.05 to 16.32 %, and 2.8 to 16 %, respectively. However, at other conditions (non-optimum), the energy consumption and evaporator air temperature were higher and within the range 0.28 to 8.26 %, and 5 to 40 % respectively, while the coefficient of performance and second law efficiency reduced within the range 2.99 to 10.94 %, and 0.55 to 13.43 % respectively. In conclusion, we observed variations in the performance of the refrigerator with varying test conditions.In the present investigation, a totally of 673 newly designed 2,6-diphenyl piperidin-4-one derivatives are docked with 2B7N protein of Helicobacter pylori which causes peptic ulcer disease. The docking studies revealed that 2,6-bis(3,4-dihydroxyphenyl)-3-phenethylpiperidin-4-one (BDPO) is identified as the most promising new compound with active nature against 2B7N with a binding affinity value of -8.0 Kcal/mol. The molecular structure of BDPO has been analyzed by DFT based theoretical calculations at the B3LYP/6-311++G(d,p) level of theory using the Gaussian 16W program package. The molecular electrostatic potential, Frontier molecular energy gap, and Mulliken population analysis have been used to understand the reactive site of the molecule. The stability and hyper-conjugative interactions were studied by natural bond orbital analysis (NBO) based on a second-order perturbation approach. The thermodynamic properties like thermal energy, specific heat capacity, and entropy at different temperatures were also calculated. The calculated first-order hyper polarizability results show that the title compound is 25.3 times greater than that of standard reference material, urea. So the title molecule is a good non-linear material. Also, this molecule has Van der Waals attraction and steric effect. It undergoes local excitation for the first five excitations.Insolvency and business recovery laws in Nigeria have not evolved to incorporate reorganisation, reforming insolvent oil firms' operations to boost commercial oil firms' steadiness and economic suitability like other moderately developed countries. In Nigeria, liquidation is understood by many as the panacea to indebtedness. NHWD-870 concentration The research evaluates the Nigerian insolvency and business recovery legal regime to sustain indebted oil firms from economic shocks due to the global decline in the oil price to avert imminent business failures due to insufficient cash flows. The aim is to fill the gaps in Nigeria's insolvency and business recovery laws by recommending a model for the sustenance of oil firms and to suggest the reform of the gaps identified in the existing laws and the extant literature on the subject. The paper opted for conceptual legal review, comparative legal and policies analyses of solvency and business recovery legislations in Nigeria, Malaysia, India, South Africa, the United Kingdom and the Unith the recommendation for further study to consider quantitative analysis research methodology to project further scholarship on the subject.This study assessed pesticide usage practices, knowledge and health effects of pesticides through occupational exposure in randomly selected horticultural farmers in Imenti North, Imenti South and Buuri Sub-counties in Meru, Kenya, where horticultural crops are grown intensively for export and local consumption. The study was done through use of questionnaire distributed to farmers' households, agricultural extension workers and health care workers. The survey established that various classes of pesticides were used in horticultural crop farming and animal production in all the three sub-counties, with the most frequently used (>60 respondents out of 173) being parathion, diazinon, dimethoate, permethrin, pirimiphos methyl, endrin, deltamethrin, dieldrin, propoxur and endosulfan. It was found that there is a gap between the existing government regulations on pesticide use and safe handling and the implementation of these regulations by dealers, farmers and farm workers in the three sub-counties as some of the pesticides that were being used such as parathion, endrin, dieldrin and carbofuran had been banned by the government.