Costelloklausen6312

Porous materials are widely employed in a wide variety of industrial applications due to their advanced functional performance. Vafidemstat mouse Porous aluminum is among the most attractive metallic materials. It can be produced using repeatable methods involving a replicated Al foam that also provides porosity control. In this work, a highly porous replicated Al foam was fabricated. First, the model of multifunctional packing density was used and corrected to select the appropriate space holders. Then, Al foam was produced using a double-granular sodium chloride space holder. The obtained results showed a maximum porosity of 65% that was achieved using a mix of coarse, irregular granules with spherical granules of intermediate size.To process data from IoTs and wearable devices, analysis tasks are often offloaded to the cloud. As the amount of sensing data ever increases, optimizing the data analytics frameworks is critical to the performance of processing sensed data. A key approach to speed up the performance of data analytics frameworks in the cloud is caching intermediate data, which is used repeatedly in iterative computations. Existing analytics engines implement caching with various approaches. Some use run-time mechanisms with dynamic profiling and others rely on programmers to decide data to cache. Even though caching discipline has been investigated long enough in computer system research, recent data analytics frameworks still leave a room to optimize. As sophisticated caching should consider complex execution contexts such as cache capacity, size of data to cache, victims to evict, etc., no general solution often exists for data analytics frameworks. In this paper, we propose an application-specific cost-capacity-aware caching scheme for in-memory data analytics frameworks. We use a cost model, built from multiple representative inputs, and an execution flow analysis, extracted from DAG schedule, to select primary candidates to cache among intermediate data. After the caching candidate is determined, the optimal caching is automatically selected during execution even if the programmers no longer manually determine the caching for the intermediate data. We implemented our scheme in Apache Spark and experimentally evaluated our scheme on HiBench benchmarks. Compared to the caching decisions in the original benchmarks, our scheme increases the performance by 27% on sufficient cache memory and by 11% on insufficient cache memory, respectively.The current COronaVIrus Disease 19 (COVID-19) pandemic caused by SARS-CoV-2 infection is enormously affecting the worldwide health and economy. In the wait for an effective global immunization, the development of a specific therapeutic protocol to treat COVID-19 patients is clearly necessary as a short-term solution of the problem. Drug repurposing and herbal medicine represent two of the most explored strategies for an anti-COVID-19 drug discovery. Clove (Syzygium aromaticum L.) is a well-known culinary spice that has been used for centuries in folk medicine in many disorders. Interestingly, traditional medicines have used clove since ancient times to treat respiratory ailments, whilst clove ingredients show antiviral and anti-inflammatory properties. Other interesting features are the clove antithrombotic, immunostimulatory, and antibacterial effects. Thus, in this review, we discuss the potential role of clove in the frame of anti-COVID-19 therapy, focusing on the antiviral, anti-inflammatory, and antithrombotic effects of clove and its molecular constituents described in the scientific literature.This study investigates the effect of defined working distances between the tip of a sandblasting device and a resin composite surface on the composite-composite repair bond strength. Resin composite specimens (Ceram.x Spectra ST (HV); Dentsply Sirona, Konstanz, Germany) were aged by thermal cycling (5000 cycles, 5-55 °C) and one week of water storage. Mechanical surface conditioning of the substrate surfaces was performed by sandblasting with aluminum oxide particles (50 µm, 3 bar, 10 s) from varying working distances of 1, 5, 10, and 15 mm. Specimens were then silanized and restored by application of an adhesive system and repair composite material (Ceram.x Spectra ST (HV)). In the negative control group, no mechanical surface pretreatment or silanization was performed. Directly applied inherent increments served as the positive control group (n = 8). After thermal cycling of all groups, microtensile repair bond strength was assessed, and surfaces were additionally characterized using scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDX). The negative control group reached the significantly lowest microtensile bond strength of all groups. No significant differences in repair bond strength were observed within the groups with varying sandblasting distances. Composite surfaces sandblasted from a distance of 1 mm or 5 mm showed no difference in repair bond strength compared to the positive control group, whereas distances of 10 or 15 mm revealed significantly higher repair bond strengths than the inherent incremental bond strength (positive control group). In conclusion, all sandblasted test groups achieved similar or higher repair bond strength than the inherent incremental bond strength, indicating that irrespective of the employed working distance between the sandblasting device and the composite substrate surface, repair restorations can be successfully performed.

To date, no crossover studies have compared the effects of high-protein (HP) and low glycemic index (LGI) diets applied as starting energy-restricted diets.

Thirty-five overweight or obese volunteers with sedentary lifestyles aged 41.4 ± 11.0 years, with body mass index (BMI) of 33.6 ± 4.2 kg/m

, without diabetes, completed an 8-week randomized crossover study of an energy-restricted diet (reduction of 30%; approximately 600 kcal/day). The anthropometric parameters, body composition, 24 h blood pressure, and basic metabolic profile were measured at baseline and after completing the two 4-week diets; i.e., the HP (protein at 30% of the daily energy intake) or LGI diet, followed by the opposite diet. All subjects maintained food diaries and attended six counselling sessions with a clinical dietitian.

The final weight loss was not significantly different when the HP diet was used first but was associated with a greater loss of fat mass 4.6 kg (5.8; 3.0 kg) vs. 2.2 (4.5; 0.8);

< 0.025, preserved muscle mass, and reduced LDL-cholesterol.