Blandschmidt1244

The purpose of this paper was to investigate the psychosocial consequences of transitioning into informal caregiving, and to investigate this association in male and female caregivers with a longitudinal design. Longitudinal panel data from the population-based German Ageing Survey (wave 2014, 2017) were used. The complete sample included up to 13,333 observations (N = 8658) pooled over waves 2014 and 2017. In total, 2.56% of the complete sample transitioned into informal caregiving (N = 547). Individuals who transitioned into informal caregiving, were on average aged 66 years and 54.48% of these participants were female. Well-established scales were used to assess the psychosocial outcomes of network size, loneliness and social isolation, depressive symptoms, as well as positive and negative affect. Transitioning into informal caregiving was used as the main predictor. Sociodemographic characteristics and physical health were controlled for. Results of fixed effects regression analyses showed that transitioning into informal caregiving was significantly associated with increased network size (b = 0.35, p less then 0.05), increased depressive symptoms (b = 0.63, p less then 0.05) and increased negative affect (b = 0.08, p less then 0.001). When stratifying the sample by gender, the results showed increased network size (b = 0.43, p less then 0.05), depressive symptoms (b = 0.93, p less then 0.01), and loneliness (b = 0.06, p less then 0.05) among male caregivers, while female caregivers reported increased negative affect (b = 0.10, p less then 0.001). The study's results extend previous research by showing that transitioning into informal caregiving is mainly associated with negative psychological outcomes. Additional analyses suggest that female and male caregivers experience different psychosocial consequences. Thus, gender should be taken into consideration when investigating informal care and its outcomes, and support should be tailored specifically to the needs of female and male caregivers.

Immunisation is a safe and effective way of protecting children and adults against harmful diseases. However, immunisation coverage of children is declining in some parts of New Zealand.

Use a nationwide sample to first, examine the socioeconomic and demographic determinants of immunisation coverage and spatial variation in these determinants. Second, it investigates change in immunisation coverage in New Zealand over time.

Individual immunisation records were obtained from the National Immunisation Register (NIR) (2005-2017; 4,482,499 events). We calculated the average immunisation coverage by year and milestone age for census area units (CAU) and then examined the immunisation coverage by selected socioeconomic and demographic determinants. Finally, local variations in the association between immunisation coverage and selected determinants were investigated using geographically weighted regression.

Findings showed a decrease of immunisation rates in recent years in CAUs with high immunisation coverage in the least deprived areas and increasing immunisation rates in more deprived areas. Nearly all explanatory variables exhibited a spatial variation in their association with immunisation coverage. For instance, the strongest negative effect of area-level deprivation is observed in the northern part of the South Island, the central-southern part of the North Island, around Auckland, and in Northland.

Our findings show that childhood immunisation coverage varies by socioeconomic and demographic factors across CAUs. We also identify important spatial variation and changes over time in recent years. This evidence can be used to improve immunisation related policy in New Zealand.

Our findings show that childhood immunisation coverage varies by socioeconomic and demographic factors across CAUs. We also identify important spatial variation and changes over time in recent years. This evidence can be used to improve immunisation related policy in New Zealand.Liew et al. (2020) recently published a paper in this journal that analyzed antidepressant prescription trends in the context of the 2016 Brexit referendum and the sociopolitical discord that followed. They present a novel finding that Leave-majority constituencies in England seemed more adversely affected by that discord than Remain-majority constituencies. I offer criticism of their findings and methodology. Selleckchem VT103 Using the complete set of available NHS prescription data shows that the trend the authors detect dates from at least mid-2010 and is not associated with the referendum. In terms of methodology, I critique the potential ecological fallacy and issues of false equivalence in their study design. The former stems from the inability to adequately control for demographic heterogeneity within constituencies, and the latter stems from the fact that the populations from which they draw their data are not equivalent in potentially important ways. Finally, I conclude that the key trend the authors detect seems to merely be a geographic artifact. The set of Remain-majority constituencies unintentionally oversamples the areas of England with the lowest rates of antidepressant prevalence, Greater London and the Southeast. Remain-majority constituencies outside of those two regions have roughly the same antidepressant prescription levels as Leave-majority constituencies in all of England. In itself, that is a troubling fact of social epidemiology, but Brexit is associated with it neither spatially nor temporally.Cyanobacteria blooms are crucial environmental issues by threatening both aquatic ecosystem and human health. A biomass by-product with antimicrobial activity, pyroligneous acid (PA) was tested for its suitability for removal of the cyanobacteria Microcystis aeruginosa (M. aeruginosa) in this work. Results show that the removal efficiency could reach up to 90% in the presence of 0.45% of PA and the inhibition to M. aeruginosa growth could extend to at least 40 days. The removal mechanism was studied. Both organic acids and phenols are functional content in M. aeruginosa removal and acetic acid is the most important one. Zeta potential analysis and morphology study show that the damage of cells dominates the flocculation and sedimentation of M. aeruginosa under low PA concentration ( less then 0.7%), and increasing PA (≥0.7%) resulted in a trend of zeta potential to zero, thus removing any "shield" and triggering flocculation. Finally, study on the phenols residual after M. aeruginosa treatment shows that it could be close to 0 in 70 h.