Chohermansen8306
Flexible, stretchable, and bendable electronics and optoelectronics have a great potential for wide applications in smart life. An environmentally friendly, cost effective and wide-angle emission laser is indispensable for the emerging technology. In this work, circumvent the challenge issue, cavity-free and stretchable white light lasers based on all carbon materials have been demonstrated by integration of fluorescent carbon quantum dots (CQDs) and crumpled graphene. The typical emission spectrum of the cavity-free laser based on all-carbon materials has a CIE chromaticity coordinate of (0.30, 0.38) exhibiting an intriguing broadband white-light emission. The unprecedented and non-toxic stretchable and white light cavity-free lasers based on all-carbon materials can serve as next-generation optoelectronic devices for a wide range application covering solid-state lighting and future wearable technologies.A closed-form model of multiphoton quantum radar cross-section (QRCS) in the monostatic scenes is constructed for rectangular flat plates based on quantum interference and uncertainty. The model is justified by the comprehensive analysis of the model parameters in the model building process. Then, we use the model to quantitatively analyze the main lobe enhancement effect of multiphoton QRCS, which means that the more incident photons will enhance the main lobe magnitude of QRCS with other factors being the same. Moreover, we predict that enhancement effects might also exist for the side lobe close to the main lobe. Baricitinib In addition, we present the specific conditions for side lobe enhancement. On this basis, the enhancement angle range is defined to unify the description of the main lobe and side lobe enhancement effects. The influencing factors of the enhancement angle range are clarified. The results exhibit that the angle range of enhancement in multiphoton QRCS fluctuates with the change of target size and incident wavelength. All enhancement effects are exponentially related to the incident photon number. This work brings the description of multiphoton QRCS into the closed-form model analysis stage, which will provide prior information for research in many fields, such as photonic technology, radar technology, and precision metrology.This paper describes the characterization of a novel directly modulated multi-section laser with a master-slave configuration. Amplitude and phase noise measurements show relative intensity noise values of around -150 dB/Hz and a 3-dB linewidth of around 3 MHz. The laser's suitability for optical access networks, enabled by the chirp reduction from the external injection locking, is shown by demonstrating unamplified 30 Gbit/s C-band transmission over 25 km and 50 km of single mode fiber using PAM4, as well as 30 Gbit/s PAM4 and PAM8 amplified transmission over 75 km.Quantum coherence has been considered as a resource for quantum information process in recent years. Sharing the quantum resource distantly is a precondition for quantum communication. In this paper, we explore the quantum coherence properties of the prepared state starting from initially incoherent thermal light source. It is shown that the quantum coherence is directly proportional to the dimension of Hilbert space and therefore employ the orbital angular momentum (OAM) to encode resources. The distribution of biphoton thermal OAM state via the one-sided noisy channel (non-Kolmogorov turbulent atmosphere) is then investigated. It is found that the prepared OAM state can have large amount of quantum coherence, which is maximized when the thermal source is completely incoherent. The turbulence effects on quantum coherence are studied and compared to those on the fidelity and quantum channel capacity. Contrasting to the monotonic decay, the dynamics of coherence displays a peak during the propagation and the mechanism behind is presented. Finally, the dynamics of quantum thermal state can be more robust than that of Bell-like pure state since more interference can be induced. We believe our results is of importance to OAM quantum communication using quantum coherence as a resource.The principle of phase-preserving regeneration is revealed by a simple theoretical model, that is, in the regenerated signals the linear phase shift component is dominant over the nonlinear counterpart for phase-preserving amplitude regeneration (PPAR). A Mach-Zehnder- interferometer (MZI)-nested nonlinear optical loop mirror (NOLM) PPAR scheme is proposed and verified by theory and experiment. Our experiment shows that for QPSK regeneration the noise reduction ratio in terms of error vector magnitude (EVM) is linearly dependent on the input signal-to-noise ratio (SNR) with the slope of 0.78 and the average phase disturbation is 4.37 degree, close to the theoretical value of 3.8 degrees. The influence of the optical couplers on the PPAR performance is in detail discussed.In this paper, a closed-loop micro-opto-electro-mechanical system (MOEMS) accelerometer based on the Fabry-Pérot (FP) interferometer is presented. The FP cavity is formed between the end of a cleaved single-mode optical fiber and the cross-section of a proof mass (PM) which is suspended by four U-shaped springs. The applied acceleration tends to move the PM in the opposite direction. The arrays of fixed and movable comb fingers produce an electrostatic force which keeps the PM in its resting position. The voltage that can provide this electrostatic force is considered as the output of the sensor. Using a closed-loop detection method it is possible to increase the measurement range without losing the resolution. The proposed sensor is fabricated on a silicon-on-insulator wafer using the bulk micromachining method. The results of the sensor characterization show that the accelerometer has a linear response in the range of ±5 g. In the closed-loop mode, the sensitivity and bias instability of the sensor are 1.16 V/g and 40 µg, respectively.We demonstrate a monolithically integrated photonic integrated circuit (PIC) for terahertz spectroscopy with wide spectral bandwidth. The PIC includes two widely tunable sampled grating DBR (SG DBR) lasers, semiconductor optical amplifiers (SOAs), and passive components to combine signals. The SG DBR lasers cover 22 nm and 24 nm tuning range, respectively, with 4 nm overlap in the C band. The side mode suppression ratio (SMSR) exceeds 37 dB with a linewidth below 4.3 MHz. We used the PIC to generate THz radiation with a state-of-the-art photodiode emitter. The measured THz power spectrum between 0.03 and 1 THz compares well with the spectrum generated with commercial tunable laser sources. This demonstrates the suitability of our PIC for future miniaturized continuous wave (cw) THz systems.COVID-19 is an emerging disease that poses a severe threat to global public health. As such, there is an urgent demand for vaccines against SARS-CoV-2, the virus that causes COVID-19. Here, we describe a virus-like nanoparticle candidate vaccine against SARS-CoV-2 produced by an E. coli expression system. The fusion protein of a truncated ORF2-encoded protein of aa 439~608 (p170) from hepatitis E virus CCJD-517 and the receptor-binding domain of the spike protein from SARS-CoV-2 were expressed, purified and characterized. The antigenicity and immunogenicity of p170-RBD were evaluated in vitro and in Kunming mice. Our investigation revealed that p170-RBD self-assembled into approximately 24 nm virus-like particles, which could bind to serum from vaccinated people (p less then 0.001) and receptors on cells. Immunization with p170-RBD induced the titer of IgG antibody vaccine increased from 14 days post-immunization and was significantly enhanced after a booster immunization at 28 dpi, ultimately reaching a peak level on 42 dpi with a titer of 4.97 log10. Pseudovirus neutralization tests showed that the candidate vaccine induced a strong neutralizing antibody response in mice. In this research, we demonstrated that p170-RBD possesses strong antigenicity and immunogenicity and could be a potential candidate for use in future SARS-CoV-2 vaccine development.Induced pluripotent stem cells (iPSCs) can be generated from somatic cells using Oct4, Sox2, Klf4, and c-Myc (OSKM). Small molecules can enhance reprogramming. Licochalcone D (LCD), a flavonoid compound present mainly in the roots of Glycyrrhiza inflata, acts on known signaling pathways involved in transcriptional activity and signal transduction, including the PGC1-α and MAPK families. In this study, we demonstrated that LCD improved reprogramming efficiency. LCD-treated iPSCs (LCD-iPSCs) expressed pluripotency-related genes Oct4, Sox2, Nanog, and Prdm14. Moreover, LCD-iPSCs differentiated into all three germ layers in vitro and formed chimeras. The mesenchymal-to-epithelial transition (MET) is critical for somatic cell reprogramming. We found that the expression levels of mesenchymal genes (Snail2 and Twist) decreased and those of epithelial genes (DSP, Cldn3, Crb3, and Ocln) dramatically increased in OR-MEF (OG2+/+/ROSA26+/+) cells treated with LCD for 3 days, indicating that MET effectively occurred in LCD-treated OR-MEF cells. Thus, LCD enhanced the generation of iPSCs from somatic cells by promoting MET at the early stages of reprogramming.
This study aimed to examine the correlations between serum hepatitis B core-related antigen (HBcrAg) and hepatitis B surface antigen (HBsAg) titers in patients with hepatitis B cirrhosis and a hepatitis B virus (HBV)-DNA-negative status.
We retrospectively analyzed the data and blood samples of patients who were diagnosed with HBV liver cirrhosis and an HBV-DNA negative status. These patients were hospitalized between October 2018 and October 2019 at one hospital.
A total of 180 patients were included. The median (interquartile range) HBsAg and HBcrAg concentrations were 2.77 log
IU/mL (1.60-3.15) and 3.96 log
U/mL (2.70-4.97), respectively. A non-linear significant relationship was found between HBsAg and HBcrAg concentrations. The inflection point was 0.58. The effect size and confidence interval on the left and right sides of the inflection point were 0.10 (-0.23-0.42) and 0.62 (0.46-0.78), respectively. When HBsAg concentrations were ≥0.58 log
IU/mL, HBsAg concentrations were positively correlated with HBcrAg concentrations. When HBsAg concentrations increased by 1 log
IU/mL, HBcrAg concentrations increased by 0.62 log
U/mL (95% confidence interval 0.46, 0.78).
There might be a non-linear relationship between HBcrAg and HBsAg concentrations in patients with hepatitis B cirrhosis and an HBV-DNA-negative status.
There might be a non-linear relationship between HBcrAg and HBsAg concentrations in patients with hepatitis B cirrhosis and an HBV-DNA-negative status.
To characterize the clinical presentation, surgical management, long-term complications and outcomes of Gunshot Wounds(GSW) to the orbit.
An extended case series with retrospective chart-review was conducted on all cases (1985-2020) of traumatic ocular injuries secondary to GSWs at an academic institution with a level 1 trauma center. Predictors included demographic information, clinical and radiologic examination findings, and surgical intervention at time of presentation. Outcomes included long-term lid malposition, visual acuity, pain, and secondary surgery. Descriptive statistics and tests of association were performed, including Fishers exact tests for categorical data, Kruskal-Wallis rank sum tests, analysis of variance, and, in the case of repeated measures, generalized estimating equations.
88 patients with GSW involving the orbit were included with average age of 32.6years (sd=15.7). Patients were 85.2% male, 75% African-American, 25.0% Caucasian, and 5.7% Hispanic. Median follow up was 43.3months (4.
