Hoodneville0885

The CFRP material was found to give good thermo-elastic characteristics at lower deposited heat power, however, this was not the case for higher deposited heat power (e.g. 200 W). AT13387 clinical trial The anisotropic property of the laminate had a significant influence in managing the thermal stresses. The study was repeated for carbon fibers doped with nanoparticles of silicon carbide (CFSiC) and resin bonded glass fiber (RBGF). It was found that the results were distinctly different when compared with the CFRP laminate. CFSiC showed to exhibit an ehanced thermo-elastic behaviour, due to the high thermal stability of SiC nanoparticles in the composite. © 2020 The Authors.The present study was aimed to investigate the in vitro and in vivo inhibitory effects of Carica papaya seeds on α-amylase and α-glucosidase enzymes, as this is known to be an antidiabetic mechanism. Analysis of the extracts of the seeds for phytochemicals revealed the presence of a significant amount of saponins, alkaloids, flavonoids, phenols, terpenoids, and steroids. The seed extracts of Carica papaya exhibited good antioxidant capacity using 2, 2-diphenyl-1-picryl hydroxyl (DPPH), thiobarbituric reactive substance (TBARS) and ferric reducing antioxidant power (FRAP) method. The results of the inhibitory studies of the extracts revealed that the hexane extract followed by the ethyl acetate extract was the most potent inhibitor of α-amylase and α-glucosidase enzyme when compared to other extracts using their IC50 values. In the animal study, different doses (250, 500 and 1000 mg/kg/body weight) of the extracts of Carica papaya seed were administered orally for 120 min, to normal and streptozotocin-induced diabetic rats, and were compared with acarbose 100 mg/kg/body weight and control group for the effect on postprandial hyperglycemia. The extract of ethyl acetate (at doses of 250, 500 and 1000 mg/kg/body weight) significantly reduced postprandial glucose levels in these animals. The characterization of hexane and ethyl acetate extracts by GC-MS analysis revealed 20 bioactive compounds while the FTIR analysis confirmed the presence of this functional groups -C=C, -C-Cl, -C-O, -O-H, -CH, -C=O, -C=C=C, -N=C=S, -O=C=O and -N-H in Carica papaya seed extracts. It was concluded that the inhibition of α-amylase and α-glucosidase enzymes and the prevention of oxidative stress in postprandial hyperglycemia could be some of the possible mechanisms by which they exert their anti-diabetic properties. © 2020 The Author(s).Objectives To examine the relationship of reduced numbers of occluding teeth and dietary intake (DI), nutrition impact symptoms (NIS), and weight loss (WL) in head and neck cancer (HNC) patients. Methods As a part of the standard of care, treatment-naïve HNC patients (n = 104) completed dental evaluation (number of teeth, total anterior/posterior occlusal teeth, Eichner Index (EI) classification), WL, DI questionnaire and HNC Symptom Checklist©. Descriptive statistics (Kruskal-Wallis, Fisher-exact, χ2 tests) and (uni-) multi-variable logistic regression. Results Overall, 42, 45 and 13% of patients were in EI-class A, B and C with a median of 8, 3, and 0 total posterior occlusal teeth. EI-class B/C patients were older, more likely to have impaired DI (OR = 3.88; 95%CI1.63-9.26; P = 0.002) and reported interference with DI by 11 NIS (p less then 0.05). DI was, however, reported as unimpaired in 77, 49 and 39% of patients in EI-class A, B and C, respectively. The subset of EI-class B/C patients with impaired DI, had more NIS interference with DI (P less then 0.05; difficulty chewing, pain, early satiety, lack of energy); EI-class C patients additionally had dry mouth, thick saliva and dysphagia (P less then 0.05). In logistic regression, EI-classes B/C patients with reduced (vs unimpaired) DI were more likely to have ≥5% WL (OR = 10.1; 95%CI2.0-50.0), higher NIS interference (range OR 4.3-10.7). Conclusions More than half of these HNC patients had reduced numbers of occlusal teeth or were edentulous. EI-class B/C patients did not necessarily have impaired DI, however the combination of EI-class B/C and a constellation of NIS, associated with reduced DI. Clinical significance Treatment naïve head and neck cancer (HNC) patients with reduced occlusal and masticatory performance (Eichner Index B/C) and reduced dietary intake are at high risk for weight loss. Identifying HNC patients at risk may improve their oral health, dietary intake and reduce their risk of weight loss. © 2020 The Authors.Malaria is a major health problem in the world particularly in sub-Saharan Africa where 90% of malaria deaths occur. Likewise malaria is one of the leading causes of morbidity and mortality in Ethiopia. It has been reported that about 75% of the country is malarious where 60% of its population is at risk of this infection. Like many African countries, Ethiopian urban settings are characterized by poor housing, lack of sanitation and drainage of surface water which provide conducive environment for the breeding of vector mosquitoes for the transmission of malaria. There are few researches on urban malaria under the urban settings of Ethiopia. The purpose of this study was to assess the magnitude of malaria cases due to Plasmodium falciparum and Plasmodium vivax in Batu town, Oromia, Ethiopia. Retrospective laboratory confirmed malaria case record data of six years (2012-2017) were used to analyze the magnitude of malaria cases due to P. falciparum and P. vivax, in Batu town, Oromia, Ethiopia. The retrospective data analysis revealed an overall 21,797 malaria confirmed cases; of which 49.5% were due to P. falciparum and 50.5% were due to P. vivax, with a slight decline in malaria between 2012 and 2017. Malaria cases were recorded in both sexes and all age groups in the study area. From the result of the present analysis it can be concluded that both P. falciparum and P. vivax were the cause for malaria cases indicating malaria is still public health problem in Batu town. Therefore, appropriate strategic control measures must be designed to protect the public and eventually eliminate malaria from the area and the country as a whole. © 2020 The Author(s).