Postmccain7020

ion to OC, from 1.6 ± 1.4 (BR) to 3.2 ± 2.0 μgC m-3 (DR), almost offset the decrease coming from the primary sources. Results from this work underscore challenges in predicting the benefits to PM2.5 improvement from emission reductions of common urban primary sources.At the nanometer scale, heat (phonon) transport is sensitive to the contact details at the interface due to the phonon wave property. However, the effects of contact atom distribution are ignored. In this work, the atomic Green's function (AGF) method and molecular dynamics (MD) simulation are applied to explore those effects. A parameter named as the average distance d[combining macron] is raised here to measure the distribution of contacted atoms at the interface. Based on the AGF method, phonon transmission profiles at different d[combining macron] (distribution) with the same number of contacted atoms have a coincident point, the reverse frequency fr. If the phonon frequency f is smaller (larger) than fr, smaller d[combining macron] has smaller (larger) phonon transmission. The overlap of the vibrational density of states from the MD simulation and the local density of states from the AGF method indicate that the reverse frequency is caused by the match degree of vibration modes across the interface. SB590885 in vivo The existence of reverse frequency leads to the reverse temperature Tr. Increasing the contact area or the interfacial coupling strength can cause the blue shift of fr and the increase of Tr. The MD simulations observe a larger temperature jump at the interface for larger d[combining macron], similar to that from the AGF method at temperatures higher than Tr due to the high-temperature limit property in MD. The results are independent of the choice of cutoff distance in potential and interfacial coupling strength, indicating that the conclusion here is applicable for the general interface.The most processable solid electrolyte, Li2S-P2S5 (LPS), exhibits the drawback of a limited potential window, which leads to the deterioration of the interface stability and limits the application of high-capacity anodes, such as those based on Li, Si, and Bi. Here, the in situ formation of a designed artificial solid electrolyte interface provides an effective way to apply low-voltage anodes in solid-state batteries.Antibiotic-associated diarrhea (AAD) is typically mediated by antibiotic therapy, which has increased in prevalence in recent years. Previous studies have suggested that ginger, a common spice and herbal medicine, can modulate the composition of gut microbiota and is beneficial against gastrointestinal disease. This study investigates the therapeutic effects of fresh ginger extract on AAD in a rat model. Gut microbiota and intestinal barrier function were also studied. Ginger was administered to rats with AAD. Diarrhea symptoms were assessed, and 16s rRNA sequencing analysis of gut microbiota was performed. An AAD model was successfully established, and ginger was found to effectively ameliorate AAD-related diarrhea symptoms. After the intervention of ginger decoction, the diversity (rather than richness) of gut microbiota was significantly improved, and the gut microbiota recovery was accelerated. At the genus level, Escherichia_Shigella and Bacteroides levels decreased and increased the most, respectively. Additionally, these changes were demonstrated to be coincidental with the moderate restoration of intestinal barrier function, especially the restoration of tight junction protein ZO-1. Our data indicate that ginger could restore gut microbiota and intestinal barrier function during alleviation of AAD.

Considerable research has suggested that race and age are two major determinants of brain development, including but not limited to development of the prefrontal cortex (PFC). Minorities' Diminished Returns (MDRs), however, suggests that race (as a proxy of racism) may interact with various determinants of human and brain development. Minimal knowledge, however, exists on whether age and race also interact on shaping PFC response to threat among American children.

Using data from a task-based functional brain imaging study and considering race as a sociological rather than a biological construct, we investigated combined effects of race and age on prefrontal cortical (PFC) response to threat. We explored racial heterogeneities in the association between age and PFC response to threat by comparing Black and White children.

This study used the task-based functional Magnetic Resonance Imaging (fMRI) data from the Adolescents Brain Cognitive Development (ABCD) study, a national, landmark, multi-center brain needed on how social stratification and racism shape emotion processing and regulation of American children in response to threat.Historians of medicine have been influential actors in a broader movement to highlight the social, institutional and administrative benefits of historical research, and its relevance for national and international policy intended to extend and improve contemporary healthcare. Historical perspectives are fundamentally useful to health policy actors because questions about what it is to be healthy, to suffer disease or disability, and the presentation and acceptance of solutions are interwoven in culturally and historically complex webs of meaning. Historians, as they have examined the social and cultural social determinants of health, have also used their work as public engagement, educational and policy resource tools, demonstrating that history is an effective way of making key issues in science, medicine and well-being more administratively responsive and accessible to lay audiences. This article explores such issues through the case study of the long-running World Health Organization (WHO) Global Health Histories project. Established in late 2004, the project's enduring rationale has been that understanding the history of health helps the global public health community to respond to the challenges of today and help shape a healthier future. It has sought to do this by bringing together researchers and policy-makers into honest and democratic conversations and exchanges of ideas. The aim has been to stimulate a fusion between historical evidence and current policy approaches to many of the most urgent health issues. This article discusses the challenges and opportunities in bringing health history and policy together, and explores the importance of explaining historical method and the need to convince policy partners how history is evidence-based, that it can access and provide useful strategic information from archives of major institutions, and, therefore, a useful contributor to making policy initiatives adaptable and acceptable within complex polities and societies.