Fabriciusgade0098
Marked thrombocytopenia causes significant bleeding in cardiovascular surgery. Herein, we describe the case of a 47-year-old woman with immune thrombocytopenia who underwent successful pulmonary valve replacement for pulmonary valve regurgitation and stenosis after complete repair of tetralogy of Fallot. Her platelet count decreased significantly to less than 5 × 109 /L on postoperative day 3, thus multiple platelet transfusions were given. Pulse steroid therapy with dexamethasone was subsequently administered systemically for 4 days. After the treatment, her platelet count started to recover. There were no significant postoperative bleeding events, and red blood cell transfusion was not required. Other than the platelet event, the postoperative course was uneventful and the patient was discharged on postoperative day 15.Many of us have watched scientists, health professionals and policy makers debate, and struggle on how to manage the Covid-19 pandemic. In that context, I've thought about what lessons I've learned from SETAC and my training as a scientist, and how they are relevant to this pandemic. Below are my three main points. This article is protected by copyright. All rights reserved.Atmospheric rivers (ARs) are narrow regions of strong horizontal water vapor transport that play important roles in the global water cycle, weather, and hydrology. Motivated by challenges in simulating ARs with state-of-the-art global models, this paper diagnoses model errors with a focus on relative contributions of moisture convergence, evaporation, and precipitation to AR column-integrated water vapor (IWV) budget. Using 20-year simulations by 24 global weather/climate models, budget terms are calculated for four AR sectors postfrontal, frontal, prefrontal, and pre-AR, with biases assessed against two reanalysis products. The results indicate that each sector is unique in terms of the dominant water vapor balance, and that the terms exhibiting the largest intermodel spread are the same terms dominating the water vapor balance in each sector. Overall, simulated bulk AR characteristics (e.g., geometry, frequency, and intensity) are more sensitive to biases in IVT convergence and IWV tendency than to biases in evaporation and precipitation, although evaporation/precipitation biases do affect key AR bulk characteristics in selected sectors. The large intermodel spread (particularly for precipitation) and, in certain cases, discrepancies between the reanalysis references themselves (particularly for precipitation types) highlight the need for observational efforts that target better constraining AR processes in weather/climate models and reanalyses.X-ray-induced luminescence computed tomography (XLCT) is an emerging molecular imaging. Challenges in improving spatial resolution and reducing the scan time in a whole-body field of view (FOV) still remain for practical in vivo applications. In this study, we present a novel XLCT technique capable of obtaining three-dimensional (3D) images from a single snapshot. find more Specifically, a customed two-planar-mirror component is integrated into a cone beam XLCT imaging system to obtain multiple optical views of an object simultaneously. Furthermore, a compressive sensing based algorithm is adopted to improve the efficiency of 3D XLCT image reconstruction. Numerical simulations and experiments were conducted to validate the single snapshot X-ray-induced luminescence computed tomography (SS-XLCT). The results show that the 3D distribution of the nanophosphor targets can be visualized much faster than conventional cone beam XLCT imaging method that was used in our comparisons while maintaining comparable spatial resolution as in conventional XLCT imaging. SS-XLCT has the potential to harness the power of XLCT for rapid whole-body in vivo molecular imaging of small animals. This article is protected by copyright. All rights reserved.The effects of silver nanoparticles (AgNPs) have been largely explored, but there is still a lack of knowledge on their effects under the predicted changes in temperature as a consequence of climate change. The aim of the present study study was to determine how leaf consumption by invertebrate shredders is affected by dietary exposure to AgNPs and AgNO3 and whether changes in temperature alter such effects. Also, responses of antioxidant enzymes were examined. In microcosms, the invertebrate shredder Limnephilus sp. was allowed to feed on alder leaves treated with AgNPs (5, 10 and 25 mg L-1 ) and AgNO3 (1 mg L-1 ), at 10ºC, 16ºC and 23ºC (6 replicates). After 5 days, the animals were transferred to clean water and allowed to feed on untreated leaves. The higher leaf consumption by the shredder was related to temperature increase and to the contamination of leaves with AgNPs and AgNO3 . Results from enzymatic activities demonstrated that AgNP contamination via food induce oxidative and neuronal stress in the shredder the activities of catalase (CAT) and superoxide dismutase (SOD) were positively correlated with total Ag accumulated in the animal body. Moreover, glutathione S-transferase (GST) activity was strongly associated with higher temperatures (23ºC). Overall results indicated that the effects of toxicants on consumption rates and enzymatic activities are modulated by temperature, and suggested that increases in temperature changes the AgNP effects on invertebrate shredder performances. This article is protected by copyright. All rights reserved.The present work describes a simple route to magnetize MIL-53(Al)-NH2 sorbent for rapid extraction of phenol residues from environmental samples. To enlarge the applications and performances of the metal-organic frameworks in the field of adsorption materials, we combined the properties of metal-organic frameworks and magnetite to shorten the extraction time and simplify the extraction process as well. In this study, a simple and quick vortex-assisted dispersive magnetic solid phase extraction method for extraction of ten United States Environmental Protection Agency's priority phenols from water samples prior to analysis by high performance liquid chromatography with photodiode array detection was proposed. The developed method exhibits a rapid enrichment of the target analytes within 10 s for extraction and 10 s for desorption. Low detection limits of 1.8-41.7 μg L-1 and quantitation limits of 6.0-139.0 μg L-1 with the relative standard deviations for intra- and inter-day analyses less than 12% were achieved.